Biliary Tract Infections: Causative Agents and Analysis of Risk Factors for Infections With Drug-Resistant Bacteria

Objective: In order to manage the antimicrobial treatment of patients with cholangitis/cholecystitis properly, it is very important to predict the potential causative pathogens arid their antimicrobial resistance patterns. The aim of this study is to provide data for empirical treatment approaches by identifying the causative agents of biliary tract infections and their antimicrobial susceptibilities, and the risk factors in patients infected with drug-resistant microorganism

Biofilm formation of panresistant Klebsiella pneumoniae

Introduction: The authors aimed to investigate the biofilm-forming features of panresistant Klebsiella pneumoniae (PRKp). Material & methods: The biofilm formations were shown under light microscope and laser scanning confocal microscopy. The optical densities of the wells were measured and classified according to biofilm-forming capacities. Results: The ratio of biofilm-forming K. pneumoniae was established to be 100%. All isolates were found to form high-level biofilms in classification compared with positive and negative controls. No significant difference was detected in the biofilm-forming capacities of K. pneumoniae strains isolated from different sample types. Conclusion: No previous study associated with PRKp isolates was identified in the literature search. There is a need for different approaches characterizing the biofilm-forming features of PRKp

Tuberculous, Pyogenic and Brucellar Spondylodiscitis: Clinical and Laboratory Features of 103 Cases

Objective: It was aimed to evaluate clinical and laboratory differences and characteristic aspects between cases that were classified in three subgroups as tuberculous spondylodiscitis (TS), pyogenic spondylodiscitis (PS) and brucellar spondylodiscitis (BS)

Acute hepatitis and pancytopenia related to non-typhoidal salmonella infection in a human immunodeficiency virus-infected patient

Non-typhoidal salmonella (NTS) are food-borne pathogens resulting in self-limiting acute gastroenteritis, but also more severe, invasive and sometimes recurrent bacteremia with atypical organ involvement in immunocompromised adults, particularly with human immunodeficiency virus (HIV) infection. Here we present a case of acute hepatitis and pancytopenia related to a non-typhoidal agent, Salmonella enterica subspecies enterica serovar Enteritidis, in an HIV-infected patient, the first case in the literature. As presented in our case, in management of NTS infection in immunocompromised patients, the first target is the control of bacteremia and then administration of antiretroviral therapy to improve patients' immunity. Therefore, underlying immunosuppression should be excluded in patients presenting with NTS bacteremia, especially in the absence of gastroenteritis. On the other hand, atypical organ involvement and abnormal laboratory findings in HIV infection should prompt investigations for opportunistic pathogens

Comparison of the In Vitro Efficacy of Various Heparin-Antibiotic Catheter Lock Solutions to the Methicillin-Resistant Staphylococcus aureus Isolates Embedded in the Biofilm

Objective: The aim of this study is to compare the efficacy of catheter lock solutions of novel antibiotics with anticoagulants against methicillin-resistant Staphylococcus aureus (MRSA) embedded in biofilm

Long-Term Follow-Up of a Patient with Spondylodiscitis after Laparoscopic Sacrocolpopexy: An Unusual Complication with a Review of the Literature.

Sacrocolpopexy is the gold standard treatment for apical compartment prolapse with reported success rates of 78-100%. Spondylodiscitis is a rare complication of sacrocolpopexy and includes a spectrum of spinal infections such as discitis, osteomyelitis, epidural abscess, meningitis, subdural empyema, and spinal cord abscess. Here we report a case of spondylodiscitis following laparoscopic sacrocolpopexy with long-term follow-up and discuss management of spondylodiscitis after abdominal sacrocolpopexy, with a review of the literature

Neuroblastoma in a dysmorphic girl with a partial duplication of 2p caused by an unbalanced translocation.

A 1-year-old female child with multiple dysmorphic features including microcephaly, hypertelorism, a short philtrum, low set ears, a narrow high arched palate, micrognathia and growth retardation was found to have a e novo chromosome abnormality including a partial duplication of the short arm of chromosome 2 and a partial deletion of the long arm of chromosome 17. The clinical features of the case shared many similarities to previous reports of trisomy 2p. Three years later, ecchymotic spots appeared around the left ocular region. Further clinical and pathological examination confirmed the diagnosis of a neuroblastoma. This is the first case of an unbalanced translocation, 46, XX, der (17), t (2; 17) (p23; q25), showing the development of a neuroblastoma in addition to the dysmorphic features. We suggest that trisomy 2p including the N-myc proto-oncogene may have predisposed the patient to the development of a neuroblastoma

Imported Malaria Caused by Plasmodium falciparum: A Global Problem

Objective: Plasmodium falciparum acquired abroad, has become the main causative malaria agent in Turkey due to the elimination of endemic P. vivax in recent years. By describing clinical, laboratory and treatment features of imported malaria cases caused by P. falciparum, we aimed to distinguish it from other infectious diseases with similar epidemiological and clinical features, such as viral haemorrhagic fevers, and therefore to ensure the recognition of this kind of deadly malaria earlier