Striatal D2/3R availability for TRD, TRD AP and healthy control subjects.

<p>Striatal D2/3 receptor (D2/3R) availability of TRD patients, TRD patients with antipsychotics (TRD AP) and healthy control subjects. The black dots represents the striatal D2/3R availability of each subject. The horizontal lines indicate the mean D2/3R availability of each group which is 0.84 for the TRD, 0.50 for the TRD AP and 0.81 for the healthy control subjects.</p

Transversal images of D2/3R availability.

<p>Transversal [123I]IBZM SPECT slices at the level of the striatum showing D2/3 receptor availability in a TRD patient, a TRD patient on antipsychotics (TRD AP), and a healthy control subject.</p

Psychopharmacological drugs used in TRD and TRD AP patients.

<p>Psychopharmacological drugs used in TRD and TRD AP patients.</p

Subject characteristics of the individuals with Body Integrity Identity Disorder (BIID).

<p>Subject characteristics of the individuals with Body Integrity Identity Disorder (BIID).</p

Reduced neural responsivity in the left premotor cortex to tactile stimulation of the leg that felt alienated in individuals with Body Integrity Identity Disorder (BIID; group×ownership interaction).

<p>The figure shows one significant cluster including the ventral (PMv; middle) and dorsal (PMd; right). This analysis assesses neural responsivity to tactile stimulation of the leg that felt alienated versus the leg that felt a normal part of the body in individuals with BIID, in comparison to stimulation of the corresponding legs in healthy controls (z>2.3, p<0.05, corrected).</p

Increased neural responsivity to tactile stimulation in individuals with Body Integrity Identity Disorder (BIID) compared to healthy controls (group main effect).

<p>The figure shows two significant clusters in the frontoparietal network and occipitotemporal cortex for the main effect of group. This analysis assesses neural responsivity to tactile stimulation of both legs, irrespective of which leg the individuals with BIID felt as alienated or as a normal part of the body (z>2.3, p<0.05, corrected). The top panels show increased activation in the ventral (PMv) and dorsal (PMd) premotor cortex, the precentral and postcentral gyri, the superior parietal lobule, and the supramarginal gyrus. The bottom left panel shows increased activation in the precuneus, and the bottom right panel the increased activation in the right insula.</p

Local maxima (thresholded at z>3.1) within the significant clusters (z>2.3, p<0.05, corrected) for the main effect of group and the group×ownership interaction.

a<p>Local maxima for clusters with >20 voxels are reported.</p