Ethically resilient teachers, what might that be? A comparison across two educational levels : pre‐school and university in South Africa

Abstract: When comparing pre‐school teachers with university lecturers, society generally acknowledges the latter as a highly skilled professional while the former does not achieve such admiration or financial reward. Upon studying this status quo, the authors introduce ethically resilient teaching as a set of seven+1 common qualities that are shared by both levels of educators. The purpose of this paper is to present these qualities, describing how they relate to the function of teaching and learning with the aim of bridging the perceived gap between these two levels of educators..

Pharmacology of acid-sensing ion channels – Physiological and therapeutical perspectives

International audienceDevelopment of the pharmacology of Acid-Sensing Ion Channels (ASICs) has become a key challenge to study their structure, their molecular and cellular functions and their physiopathological roles. This review provides a summary of the different compounds that directly interact with these channels, either with inhibitory or stimulatory effect, and with high selectivity or poor specificity. They include drugs and endogenous regulators, natural compounds of vegetal origin, and peptides isolated from animal venoms. The in vivo use of some of these pharmacological modulators in animal models and a few small clinical studies in humans have provided substantial data on the physiological and physiopathological roles of ASIC channels. Modulation of these channels will certainly provide new therapeutic opportunities in neurological and psychiatric diseases including pain, stroke, epilepsy, anxiety, depression or traumatic injury, as well as in some non-neurological pathologies

Trading Water and Resource Accessibility Conventions. The case of Sub-Saharian Africa(n) Metropolis (cities?) (In French)

The issue of the accessibility to drinking water in large Sub-Saharian African Metropolis reveals the emergence of new conventions and new perceptions related to this resource. The current context shows an increasing number of actors. Since the 90’s, new norms are required to guide public-private partnerships engaged in redefining structural adjustment programs and in implementing a good governance. Moreover , Water can be considered as a primary resource but also as a public service and therefore induces new questionings about the link between efficacy and equity. Within an Economics of Convention approach it is possible to depart from traditional analysis based on economic efficacy as a central principle. By considering an approach beyond one in terms of strategic conventions our assumption is that a convention is based on an evaluation model and on behavioral rules. With this distinction it then possible to define four types of conventions that we call “human right”, “community”, “general interest”, “trade”. These constitute archetypes allowing the analysis of historical evolution of conventions and their interactions in Sub-Saharian African cities. Instead of simply identifying behavioral rules (state-owned company, delegation of public utilities, customery rules) our aim is to detect the underlying interpretation model. This is important because, in the end, the link between efficacy and equity is closely dependant on it. Thus, Economics of Conventions can highlight that beyond the “trading” principle other evaluation schemes exist and that the choice of a given principle stems from political choices. The issue of links between economics and politics is therefore of major importance in such a field.governance, public-private partnership, non-trading company, urban services in Sub-Saharian Africa, accessibility to drinking watere, solidarity, efficiency/equity, Economie of conventions

Alexandre Péraud, Le Crédit dans la poétique balzacienne

Après avoir entendu Balzac lire Mercadet, Théophile Gautier s’effare des proportions prises par la Dette. Et c’est à ce personnage-pivot de la pièce, devenue Le Faiseur, que la presse a comparé Madoff en 2009. C’est dire l’importance de Balzac comme créateur de la «fiction d’argent» fondée sur une circulation effrénée de la monnaie fiduciaire qui préfigure nos crises actuelles. Alexandre Péraud analyse avec une grande finesse le lien privilégié entre monnaie et fiction, entre récit de crédit ..

Paradigmes de l’âme. Littérature et aliénisme au xixe siècle, sous la direction de Jean-Louis Cabanès, Didier Philippot et Paolo Tortonese

Cet ouvrage collectif a pour postulat la convergence historique entre l’émergence de l’aliénisme et la révolution romantique. Comme le rappelle Didier Philippot dans son introduction (Romantisme et aliénisme, pp. 7-20), médecine et littérature se fécondent ainsi à travers certains paradigmes qui structurent la pensée du xixe siècle: le rapport du normal et du pathologique, la question centrale de l’imaginaire et le paradigme de l’aliénation. Peut-on alors faire l’hypothèse d’un monisme ontolo..

Honoré de Balzac, Illusions perdues

Seule la mention «Folio classique» sur la couverture et sur la tranche distingue depuis 1994 cette collection de poche où sont présentées des éditions commentées des grands classiques de la littérature française et étrangère de l’Antiquité au début du xxe siècle par un spécialiste de l’auteur ou de la période, enrichies d’un dossier comportant une préface, une bibliographie, une chronologie, un appareil de notes fourni. Jacques Noiray, grand dix-neuviémiste, balzacien éminent, présente Illusi..

Community economic development in Boston : the challenge of the eighties

Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1985.MICROFICHE COPY AVAILABLE IN ARCHIVES AND ROTCH.Bibliography: leaves 123-125.by Anne Baron Wilson.M.C.P

Honoré de Balzac, Illusions perdues

Seule la mention «Folio classique» sur la couverture et sur la tranche distingue depuis 1994 cette collection de poche où sont présentées des éditions commentées des grands classiques de la littérature française et étrangère de l’Antiquité au début du xxe siècle par un spécialiste de l’auteur ou de la période, enrichies d’un dossier comportant une préface, une bibliographie, une chronologie, un appareil de notes fourni. Jacques Noiray, grand dix-neuviémiste, balzacien éminent, présente Illusi..

Transmission of New Bovine Prion to Mice

We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrPres). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrPres molecular features distinct from BSE

Venom toxins in the exploration of molecular, physiological and pathophysiological functions of acid-sensing ion channels

International audienceAcid-sensing ion channels (ASICs) are voltage-independent proton-gated cation channels that are largely expressed in the nervous system as well as in some non-neuronal tissues. In rodents, six different isoforms (ASIC1a, 1b, 2a, 2b, 3 and 4) can associate into homo-or hetero-trimers to form a functional channel. Specific polypeptide toxins targeting ASIC channels have been isolated from the venoms of spider (PcTx1), sea anemone (APETx2) and snakes (MitTx and mambalgins). They exhibit different and sometimes partially overlapping pharmacological profiles and are usually blockers of ASIC channels, except for MitTx, which is a potent activator. This review focuses on the use of these toxins to explore the structure-function relationships, the physiological and the pathophysiological roles of ASIC channels, illustrating at the same time the therapeutic potential of some of these natural compounds