1,136 research outputs found

    Mechanisms of particle migration in electrostatic precipitators

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    Electrostatic precipitators are high efficiency gas cleaning devices widely used in industry for removing particulates from process gases. A major factor affecting their performance is particle migration, which is governed by the complex interaction of electrical and hydrodynamic phenomena. A fuller understanding of these fundamental mechanisms is therefore essential to the development of realistic mathematical models. The work described in this thesis concentrates on the fluid-particle interactions in a wire-plate-system. A pilot-scale rig was built using actual components from an industrial precipitator, allowing realistic conditions to be simulated in the laboratory. Hot-wire anemometry and laser-Doppler photon correlation techniques were employed to study the time-averaged velocity field. Several designs of wall strengthener were considered, and in each case the effect on the surrounding flow field was investigated using helium bubble visualisation. The turbulent nature of the fluid was characterised by local dispersion coefficient values and fluctuating velocity components. Alumina test dust in the size range 1-10 pm was used in the precipitator under a variety of operating conditions, and a technique was established for extracting representative dust samples. The samples allowed simultaneous measurement of concentration and size distribution, from which concentration profile development and collection efficiency information was obtained. Two alternative numerical models of the precipitator were developed, both incorporating the results from the fluid flow field experimentation. The first approach was based on the finite difference solution of the convective-diffusion equation, using appropriate boundary conditions. In the second approach, the transport of dust down the precipitator duct was simulated by the step-wise progression of a series of vertical line-sources, whose motion was governed by electrical migration and lateral diffusive spread. The validity of the models was tested by comparison of the predicted concentration profiles with corresponding experimental results

    Movin\u27 on Up: An Examination of Value-Added Growth During School Transition Years in Arkansas

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    This study assesses the impact school transitions have on grade-level value-added growth scores in Arkansas. Arkansas is unique in that the autonomy of setting building level transitions is left to individual districts. This distinction allows researchers to make comparisons between student groups that where students transitioned upward to a new building and those who did not. Using data covering five different school years, this study evaluates mathematics and English language-arts value-added growth scores of grade levels that transitioned to a new building and compared them to grade-level growth scores of buildings where students did not make a transition. Using regression analyses, we find that overall, there are not consistent results showing less growth during a transition year. However, we find a pattern that shows that students who transition in 6th and 7th grade, common transition years in Arkansas, demonstrate lower value-added growth-scores compared to student groups who did not transition. These results are similar for both mathematics and ELA. This study adds to current literature about value-added growth in Arkansas. We discuss our findings in the context of prior transition year literature and conclude with policy suggestion

    Exploration of Academic Outcomes in Arkansas\u27s Four-Day School Weeks and Year-Round Calendars

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    This brief provides an overview of the findings from a research report examining the academic outcomes of Arkansas school districts using a four-day school week or year-round calendar. We aim to shed light on trends related to academic outcomes. We assess the impacts of recent calendar changes in this context and make recommendations

    Improving the School Context of Early Adolescence Through Teacher Attunement to Victimization: Effects on School Belonging

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    The present study examined the effects of teacher attunement to victimization on student perceptions of the bullying culture of their schools as a means of fostering a sense of belonging among early adolescents. Participants (n = 1,264) in sixth grade reported on the frequency that they had been bullied, and teachers were asked to report students who were “picked on.” Teacher attunement represented the correspondence between self-identified and teacher-identified victims. Attunement at the beginning of the school year was related to positive changes in student reports that their peers would intervene in bullying; in turn, sense of belonging was greater when students perceived that their peers would intervene in bullying. Teacher attunement was indirectly related to greater belonging through its impact on student perceptions of the bullying context

    Using mobile sensing data to assess stress: Associations with perceived and lifetime stress, mental health, sleep, and inflammation

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    Background Although stress is a risk factor for mental and physical health problems, it can be difficult to assess, especially on a continual, non-invasive basis. Mobile sensing data, which are continuously collected from naturalistic smartphone use, may estimate exposure to acute and chronic stressors that have health-damaging effects. This initial validation study validated a mobile-sensing collection tool against assessments of perceived and lifetime stress, mental health, sleep duration, and inflammation. Methods Participants were 25 well-characterized healthy young adults (Mage = 20.64 years, SD = 2.74; 13 men, 12 women). We collected affective text language use with a custom smartphone keyboard. We assessed participants’ perceived and lifetime stress, depression and anxiety levels, sleep duration, and basal inflammatory activity (i.e. salivary C-reactive protein and interleukin-1β). Results Three measures of affective language (i.e. total positive words, total negative words, and total affective words) were strongly associated with lifetime stress exposure, and total negative words typed was related to fewer hours slept (all large effect sizes: r = 0.50 – 0.78). Total positive words, total negative words, and total affective words typed were also associated with higher perceived stress and lower salivary C-reactive protein levels (medium effect sizes; r = 0.22 – 0.32). Conclusions Data from this initial longitudinal validation study suggest that total and affective text use may be useful mobile sensing measures insofar as they are associated with several other stress, mental health, behavioral, and biological outcomes. This tool may thus help identify individuals at increased risk for stress-related health problems

    Herbal medicine: women's views, knowledge and interaction with doctors: a qualitative study

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    BACKGROUND: There is growing concern that serious interactions are occurring between prescribed/over the counter and herbal medicines and that there is a lack of disclosure of herbal use by patients to doctors. This study explores women's perspectives about the safety of herbal remedies, herb-drug interactions and communication with doctors about herbal medicines. METHODS: Qualitative, cross-sectional study, with purposive sampling which took place in Cheshire, UK. Eighteen in depth semi-structured interviews were conducted with female herbal medicine users aged 18 years and above. RESULTS: The large majority did not inform their GPs of their use of herbal medicines. This was due to lack of physician enquiry, perception of importance and fear of a negative response. Several women were not aware that herbal remedies could interact with prescribed or over the counter medicines. Of the women who had experienced adverse effects none had reported them, believing them of low importance. CONCLUSION: The women had little knowledge about herb-drug interactions and rarely disclosed use of herbal medicines to their doctor. Doctors' communication and openness regarding herbal medicines needs to improve and there should be increased access to accurate information on herbal medicines in the public and health care domain

    Guiding principles for determining work shift duration and addressing the effects of work shift duration on performance, safety, and health

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    The article of record as published may be found at http://dx.doi.org/10.1093/sleep/zsab161Risks associated with fatigue that accumulates during work shifts have historically been managed through working time arrangements that specify fixed maximum durations of work shifts and minimum durations of time off. By themselves, such arrangements are not sufficient to curb risks to performance, safety, and health caused by misalignment between work schedules and the biological regulation of waking alertness and sleep. Science-based approaches for determining shift duration and mitigating associated risks, while addressing operational needs, require: 1) a recognition of the factors contributing to fatigue and fatigue-related risks; 2) an understanding of evidence-based countermeasures that may reduce fatigue and/or fatigue-related risks; and 3) an informed approach to selecting workplace-specific strategies for managing work hours. We propose a series of guiding principles to assist stakeholders with designing a shift duration decision-making process that effectively balances the need to meet operational demands with the need to manage fatigue-related risks.Academy of Sleep Medicine (AASM)Sleep Research Societ

    Quantifying the energy balance between the turbulent ionised gas and young stars

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    We investigate the ionised gas morphology, excitation properties, and kinematics in 19 nearby star-forming galaxies from the PHANGS-MUSE survey. We directly compare the kinetic energy of expanding superbubbles and the turbulent motions in the interstellar medium with the mechanical energy deposited by massive stars in the form of winds and supernovae, with the aim to answer whether the stellar feedback is responsible for the observed turbulent motions and to quantify the fraction of mechanical energy retained in the superbubbles. Based on the distribution of the flux and velocity dispersion in the Hα\alpha line, we select 1484 regions of locally elevated velocity dispersion (σ\sigma(Hα\alpha)>45 km/s), including at least 171 expanding superbubbles. We analyse these regions and relate their properties to those of the young stellar associations and star clusters identified in PHANGS-HST data. We find a good correlation between the kinetic energy of the ionised gas and the total mechanical energy input from supernovae and stellar winds from the stellar associations, with a typical efficiency of 10-20%. The contribution of mechanical energy by the supernovae alone is not sufficient to explain the measured kinetic energy of the ionised gas, which implies that pre-supernova feedback in the form of radiation/thermal pressure and winds is necessary. We find that the gas kinetic energy decreases with metallicity for our sample covering Z=0.5-1.0 Zsun, reflecting the lower impact of stellar feedback. For the sample of superbubbles, we find that about 40% of the young stellar associations are preferentially located in their rims. We also find a slightly higher (by ~15%) fraction of the youngest (1-2.5 Myr) stellar associations in the rims of the superbubbles than in the centres, and the opposite for older associations, which implies possible propagation or triggering of star formation.Comment: 31 pages (including 5 pages in appendix), 19 figures, the abstract is abridged; submitted to A&A (in mid May; awaiting report

    Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress

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    Abstract Disruption of the insulin-PI3K-Akt signalling pathway in kidney podocytes causes endoplasmic reticulum (ER) stress, leading to podocyte apoptosis and proteinuria in diabetic nephropathy. We hypothesised that by improving insulin sensitivity we could protect podocytes from ER stress. Here we use established activating transcription factor 6 (ATF6)- and ER stress element (ERSE)-luciferase assays alongside a novel high throughput imaging-based C/EBP homologous protein (CHOP) assay to examine three models of improved insulin sensitivity. We find that by improving insulin sensitivity at the level of the insulin receptor (IR), either by IR over-expression or by knocking down the negative regulator of IR activity, protein tyrosine-phosphatase 1B (PTP1B), podocytes are protected from ER stress caused by fatty acids or diabetic media containing high glucose, high insulin and inflammatory cytokines TNFα and IL-6. However, contrary to this, knockdown of the negative regulator of PI3K-Akt signalling, phosphatase and tensin homolog deleted from chromosome 10 (PTEN), sensitizes podocytes to ER stress and apoptosis, despite increasing Akt phosphorylation. This indicates that protection from ER stress is conferred through not just the PI3K-Akt pathway, and indeed we find that inhibiting the MEK/ERK signalling pathway rescues PTEN knockdown podocytes from ER stress

    PHANGS-HST Catalogs for ∼100,000 Star Clusters and Compact Associations in 38 Galaxies. I. Observed Properties

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    We present the largest catalog to date of star clusters and compact associations in nearby galaxies. We have performed a V-band-selected census of clusters across the 38 spiral galaxies of the PHANGS–Hubble Space Telescope (HST) Treasury Survey, and measured integrated, aperture-corrected near-ultraviolet-U-B-V-I photometry. This work has resulted in uniform catalogs that contain ∼20,000 clusters and compact associations, which have passed human inspection and morphological classification, and a larger sample of ∼100,000 classified by neural network models. Here, we report on the observed properties of these samples, and demonstrate that tremendous insight can be gained from just the observed properties of clusters, even in the absence of their transformation into physical quantities. In particular, we show the utility of the UBVI color–color diagram, and the three principal features revealed by the PHANGS-HST cluster sample: the young cluster locus, the middle-age plume, and the old globular cluster clump. We present an atlas of maps of the 2D spatial distribution of clusters and compact associations in the context of the molecular clouds from PHANGS–Atacama Large Millimeter/submillimeter Array. We explore new ways of understanding this large data set in a multiscale context by bringing together once-separate techniques for the characterization of clusters (color–color diagrams and spatial distributions) and their parent galaxies (galaxy morphology and location relative to the galaxy main sequence). A companion paper presents the physical properties: ages, masses, and dust reddenings derived using improved spectral energy distribution fitting techniques
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