Osteopathic manipulation as a complementary treatment for the prevention of cardiac complications: 12-Months follow-up of intima media and blood pressure on a cohort affected by hypertension.

BACKGROUND: Aim of the present study was to investigate the association between osteopathic treatment and hypertension. METHODS: The design was a non-randomized trial including consecutive subjects affected by hypertension and vascular alterations, using pre-post differences in intima-media thickness, systolic and diastolic blood pressure as primary endpoints. Statistical analysis was based on univariate t tests and multivariate linear regression. RESULTS: A total of N = 31 out of N = 63 eligible subjects followed by a single cardiologist received osteopathic treatment in addition to routine care. Clinical measurements were recorded at baseline and after 12 months. Univariate analysis found that osteopathic treatment was significantly associated to an improvement in all primary endpoints. Multivariate linear regression showed that, after adjusting for all potential confounders, osteopathic treatment was performing significantly better for intima-media thickness (delta between pre-post differences in treated and control groups: -0.517; 95% c.i.: -0.680, -0.353) and systolic blood pressure (-4.523; -6.291, -2.755), but not for diastolic blood pressure. CONCLUSION: Our study shows that, among patients affected by cardiovascular disorders, osteopathic treatment is significantly associated to an improvement in intima-media and systolic blood pressure after one year. Multicentric randomized trials of adequate sample size are needed to evaluate the efficacy of OMT in the treatment of hypertension

Osteopathic manipulation as a complementary treatment for the prevention of cardiac complications: 12-Months follow-up of intima media and blood pressure on a cohort affected by hypertension.

BACKGROUND: Aim of the present study was to investigate the association between osteopathic treatment and hypertension. METHODS: The design was a non-randomized trial including consecutive subjects affected by hypertension and vascular alterations, using pre-post differences in intima-media thickness, systolic and diastolic blood pressure as primary endpoints. Statistical analysis was based on univariate t tests and multivariate linear regression. RESULTS: A total of N = 31 out of N = 63 eligible subjects followed by a single cardiologist received osteopathic treatment in addition to routine care. Clinical measurements were recorded at baseline and after 12 months. Univariate analysis found that osteopathic treatment was significantly associated to an improvement in all primary endpoints. Multivariate linear regression showed that, after adjusting for all potential confounders, osteopathic treatment was performing significantly better for intima-media thickness (delta between pre-post differences in treated and control groups: -0.517; 95% c.i.: -0.680, -0.353) and systolic blood pressure (-4.523; -6.291, -2.755), but not for diastolic blood pressure. CONCLUSION: Our study shows that, among patients affected by cardiovascular disorders, osteopathic treatment is significantly associated to an improvement in intima-media and systolic blood pressure after one year. Multicentric randomized trials of adequate sample size are needed to evaluate the efficacy of OMT in the treatment of hypertension

Effect of osteopathic manipulative treatment on gastrointestinal function and length of stay of preterm infants: an exploratory study.

BACKGROUND: Organizational improvement of neonatal intensive care units requires strict monitoring of preterm infants, including routine assessment of physiological functions of the gastrointestinal system and optimized procedures for the definition of appropriate discharge timing. METHODS: We conducted a prospective study on the effect of osteopathic manipulative treatment in a cohort of N = 350 consecutive premature infants admitted to a neonatal intensive care unit without any major complication between 2005 and 2008. In addition to ordinary care, N = 162 subjects received osteopathic treatment. Endpoints of the study were differences between study and control groups in terms of excessive length of stay and gastrointestinal symptoms, defined as the upper quartiles in the distribution of the overall population. Statistical analysis was based on crude and adjusted odds ratios from multivariate logistic regression. RESULTS: Baseline characteristics were evenly distributed across treated/control groups, except for the rate of infants unable to be oral fed at admission, significantly higher among those undergoing osteopathic care (p = .03). Osteopathic treatment was significantly associated with a reduced risk of an average daily occurrence of gut symptoms per subject above .44 (OR = 0.45; 0.26-0.74). Gestational age lower or equal to 32 weeks, birth weight lower or equal to 1700 grams and no milk consumption at admission were associated with higher rates of length of stay in the unit of at least 28 days, while osteopathic treatment significantly reduced such risk (OR = 0.22;0.09-0.51). CONCLUSIONS: In a population of premature infants, osteopathic manipulative treatment showed to reduce a high occurrence of gastrointestinal symptoms and an excessive length of stay in the NICU. Randomized control studies are needed to generalize these results to a broad population of high risk newborns

Cinématique intervertébrale et costo-vertébrale in vivo dans la mécanique respiratoire: Étude préliminaire de l’axe hélicoïdal et représentation anatomique du mouvement par modélisation

Contexte :le complexe articulaire costo-vertébral est décrit comme pouvant être impliqué tant dans la fonction respiratoire que dans la stabilité du rachis thoracique. D’un point de vue fonctionnel, le thorax a régulièrement été étudié pour comprendre la relation physiologique entre les mouvements musculo-squelettiques thoraciques et les échanges gazeux pulmonaires. Quelques études rapportent différentes donnéesin vitro, principalement sur le comportement mécanique en charge et la cinématique de la jonction costo-vertébrale (JCV). Actuellement il subsiste un réel manque de données in vivo concernant la cinématique costo-vertébrale tant pour des conditions physiologiques normales que dans des situations cliniques.Méthode :dans cette étude, des acquisitions tomodensitométriques ont été réalisées dans trois positions respiratoires différentes (Capacité pulmonaire totale, Capacité inspiratoire moyenne, Capacité résiduelle fonctionnelle). Les amplitudes de mouvement ont été obtenues par la méthode des OVP (Orientation Vector Position). La méthode de l’axe hélicoïdal moyen a permis d’obtenir une visualisation segmentaire de l’axe fonctionnel des JCV.Résultats :les données cinématiques ainsi qu’une représentation anatomique du mouvement ont été obtenues bilatéralement pour les JCV des sept premières paires de côtes. L’étude de l’axe hélicoïdal moyen montre des orientations variables selon le niveau considéré.Interprétation :cette étude présente une méthode originale d’analyse cinématique de la jonction costo-vertébrale en y ajoutant une représentation anatomique du mouvement ainsi que de l’axe fonctionnel. Une analyse sur un échantillon plus large est indispensable pour renforcer la pertinence de ces résultats préliminaires avant d’investiguer l’influence de différentes conditions cliniques sur la biomécanique du thorax.info:eu-repo/semantics/publishe