57 research outputs found

    Jesuit Law Schools: Challenging the Mainstream

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    The First Conference of Religiously Affiliated Law Schools: An Overview

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    College of Liberal Arts and Sciences_Publication of Texbook Featuring Material Related to the Pandemic

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    Email thread featuring messages from Steven Barkan, Professor and chairperson, Sociology Department, University of Maine to Timothy M. Cole Associate Dean for Academics, College of Liberal Arts and Sciences Associate Professor of Political Science University of Maine and Jonathon Jue-Wong, Administrative Coordinator, The Office of the Executive Vice President for Academic Affairs & Provost, regarding the second edition of Professor Barkan\u27s textbook, Social Problems: Continuity and Change, that features material related to the COVID-19 pandemic

    College of Natural Sciences, Forestry, and Agriculture_COVID-19 Related Work Email

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    Email thread featuring messages from Michael Haedicke to Steven Barkan, Professor and chairperson, Sociology Department, University of Maine and Steven Barkan to Timothy M. Cole Associate Dean for Academics, College of Liberal Arts and Sciences Associate Professor of Political Science University of Maine regarding articles Professor Haedicke authored on subjects related to the COVID-19 pandemic

    Nowhere to Run; Nowhere to Hide: The Reality of Being a Law Library Director in Times of Great Opportunity and Significant Challenges

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    This is an edited version of remarks presented at \u27Nowhere to Run, Nowhere to Hide\u27: The Reality of Being a Law Library Director in Times of Great Opportunity and Significant Challenges, January 5, 2015, at the Association of American Law Schools Annual Meeting, Washington, D.C

    Significant benefits of AIP testing and clinical screening in familial isolated and young-onset pituitary tumors

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    Context Germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are responsible for a subset of familial isolated pituitary adenoma (FIPA) cases and sporadic pituitary neuroendocrine tumors (PitNETs). Objective To compare prospectively diagnosed AIP mutation-positive (AIPmut) PitNET patients with clinically presenting patients and to compare the clinical characteristics of AIPmut and AIPneg PitNET patients. Design 12-year prospective, observational study. Participants & Setting We studied probands and family members of FIPA kindreds and sporadic patients with disease onset ≤18 years or macroadenomas with onset ≤30 years (n = 1477). This was a collaborative study conducted at referral centers for pituitary diseases. Interventions & Outcome AIP testing and clinical screening for pituitary disease. Comparison of characteristics of prospectively diagnosed (n = 22) vs clinically presenting AIPmut PitNET patients (n = 145), and AIPmut (n = 167) vs AIPneg PitNET patients (n = 1310). Results Prospectively diagnosed AIPmut PitNET patients had smaller lesions with less suprasellar extension or cavernous sinus invasion and required fewer treatments with fewer operations and no radiotherapy compared with clinically presenting cases; there were fewer cases with active disease and hypopituitarism at last follow-up. When comparing AIPmut and AIPneg cases, AIPmut patients were more often males, younger, more often had GH excess, pituitary apoplexy, suprasellar extension, and more patients required multimodal therapy, including radiotherapy. AIPmut patients (n = 136) with GH excess were taller than AIPneg counterparts (n = 650). Conclusions Prospectively diagnosed AIPmut patients show better outcomes than clinically presenting cases, demonstrating the benefits of genetic and clinical screening. AIP-related pituitary disease has a wide spectrum ranging from aggressively growing lesions to stable or indolent disease course
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