Meson decay in an independent quark model

Leptonic decay widths and leptonic decay constants of light vector mesons and weak leptonic decay widths and weak decay constants of light and heavy pseudoscalar mesons have been studied in a field- theoretic framework based on the independent quark model with a scalar- vector power-law potential. The results are in very good agreement with the experimental data.Comment: 13 page

Characterization Of Glipizide-Loaded Polymethacrylate Microspheres Prepared By An Emulsion Solvent Evaporation Method

Purpose: The purpose of the present investigation was to formulate and evaluate microencapsulated glipizide produced by the emulsion – solvent evaporation method, Method: Microspheres were prepared using polymethacrylate polymers (Eudragit® RS 100 and RL 100) by solvent evaporation method and characterized for their micromeritic properties and drug loading, as well as by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy. In vitro release studies were performed in phosphate buffer (pH 7.4). Result: The resulting microspheres obtained by solvent evaporation method were white and free flowing in nature. The mean particle size of microspheres ranged from 420 - 660 μm and the encapsulation efficiencies ranged from 40.27 - 86.67 %. The encapsulation efficiency was also found to be dependant on nature of polymer used in the formulation. The infrared spectra confirmed the stable character of glipizide in the drug-loaded microspheres. Scanning electron microscopy revealed that the microspheres were spherical in nature. From the in vitro drug dissolution studies it was found that the sustaining effect of microspheres depended on the polymer concentration, amount of dispersant used and the type of polymer used in the formulation. The mechanism of drug release from the microspheres was found to be non-Fickian type. Conclusion: Eudragit® microspheres containing glipizide could be prepared successfully by using an emulsion solvent evaporation technique using polymethacrylate polymers, which will not only sustain the release of drug but also manage the complicacy of the diabetes in a better manner. Keywords: glipizide, Eudragit®, microspheres, controlled release, polymethacrylate.Tropical Journal of Pharmaceutical Research Vol. 7 (1) 2008: pp. 879-88

FogGIS: Fog Computing for Geospatial Big Data Analytics

Cloud Geographic Information Systems (GIS) has emerged as a tool for analysis, processing and transmission of geospatial data. The Fog computing is a paradigm where Fog devices help to increase throughput and reduce latency at the edge of the client. This paper developed a Fog-based framework named Fog GIS for mining analytics from geospatial data. We built a prototype using Intel Edison, an embedded microprocessor. We validated the FogGIS by doing preliminary analysis. including compression, and overlay analysis. Results showed that Fog computing hold a great promise for analysis of geospatial data. We used several open source compression techniques for reducing the transmission to the cloud.Comment: 6 pages, 4 figures, 1 table, 3rd IEEE Uttar Pradesh Section International Conference on Electrical, Computer and Electronics (09-11 December, 2016) Indian Institute of Technology (Banaras Hindu University) Varanasi, Indi

Evolution of Generalized Brans-Dicke parameter within a Superbounce scenario

We have studied a superbounce scenario in a set up of Brans-Dicke (BD) theory. The BD parameter is considered to be time dependent and is assumed to evolve with the Brans-Dicke scalar field. In the superbounce scenario, the model bounces at an epoch corresponding to a Big Crunch provided the ekpyrotic phase continues until that time. Within the given superbounce scenario, we investigate the evolution of the BD parameter for different equations of state. We chose an axially symmetric metric that has an axial symmetry along the x-axis. The metric is assumed to incorporate an anisotropic expansion effect. The effect of asymmetric expansion and the anisotropic parameter on the evolving and the non-evolving part of the BD parameter is investigated.Comment: 10 pages, 5 figures, accepted version of the journal Symmetr

Probing Internal Stress and Crystallinity in Wet Foam via Raman Spectroscopy

In this article, we correlate the internal stress and the characteristics of a vibrational mode in wet foam. Using microscope images, we estimate the average size of the bubbles in wet foam, at specific time intervals, over a duration of twenty four hours. Raman spectra are also recorded at the same time intervals, over the same time frame. We show that the internal stress, originated from the macroscopic structural change of foam with ageing, can be related to the observed Raman shift of the low frequency methylene rocking mode of the constituent surfactant molecules in foam. In this report we also show the capability of the Raman spectroscopy to reveal the crystallinity in foamy materials, when studied for a longer period of time.Comment: 16 pages, 7 figure

Formulation and in vitro Evaluation of Eudragit® Microspheres of Stavudine

Purpose: The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of a highly water-soluble drug, stavudine, using Copolymers synthesized from acrylic and methacrylic acid esters (Eudragit RS 100 and RL 100) as the retardant material. . Methods: Microspheres were prepared by solvent evaporation method using an acetone / liquid paraffin system. Magnesium stearate was used as the droplet stabilizer and n-hexane was added to harden the microspheres. The prepared microspheres were characterized for their micromeritic properties and drug loading, as well by fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry, x-ray powder diffractometry and scanning electron microscopy. The in vitro release studies were performed in pH 6.8, phosphate buffer. Results: The prepared microspheres were white, free flowing and spherical in shape. The drug-loaded microspheres showed 67-91% of entrapment and release was extended upto 6 to 8 h. The infrared spectra and differential scanning calorimetry thermographs showed stable character of stavudine in the drug-loaded microspheres and revealed the absence of drug-polymer interactions. X-ray diffraction patterns showed that there was decrease in crystallinity of the drug. Scanning electron microscopy study revealed that the microspheres were spherical and porous in nature. Conclusion: The best-fit release kinetics was achieved with Higuchi plot followed by zero order and First order. The release of stavudine was influenced by the drug to polymer ratio and particle size & was found to be diffusion controlled. Keywords: Stavudine, Eudragit, microspheres, controlled release, polymethacrylate > Tropical Journal of Pharmaceutical Research Vol. 4 (1) 2005: pp. 369-37