15,863 research outputs found
The uniqueness of the invariant polarisation-tensor field for spin-1 particles in storage rings
We argue that the invariant tensor field introduced in [1] is unique under
the condition that the invariant spin field is unique, and thereby complete
that part of the discussion in that paper.Comment: 8 page
Finite size scaling of the correlation length above the upper critical dimension
We show numerically that correlation length at the critical point in the
five-dimensional Ising model varies with system size L as L^{5/4}, rather than
proportional to L as in standard finite size scaling (FSS) theory. Our results
confirm a hypothesis that FSS expressions in dimension d greater than the upper
critical dimension of 4 should have L replaced by L^{d/4} for cubic samples
with periodic boundary conditions. We also investigate numerically the
logarithmic corrections to FSS in d = 4.Comment: 5 pages, 6 postscript figure
Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression
<p><b>Background and Purpose:</b> Early clinical progression of ischemic stroke is common and is associated with increased risk of death and dependency. We hypothesized that activation of the coagulation system is an important contributor in some cases of deterioration. We aimed to characterize alterations in circulating hemostatic markers in patients with progressing stroke.</p>
<p><b>Methods:</b> Consecutive acute ischemic stroke admissions were recruited. Progressing stroke was defined by deterioration in components of the Scandinavian Stroke Scale. Hemostatic markers (coagulation factors VIIc, VIIIc, and IXc, prothrombin fragments 1+2 [F1+2], thrombin-antithrombin complexes [TAT], D- dimer, fibrinogen, von Willebrand factor [vWF] and tissue plasminogen activator) were measured within 24 hours of symptom recognition.</p>
<p><b>Results:</b> Fifty-four (25%) of the 219 patients met criteria for progressing stroke. F1+2 (median 1.28 versus 1.06 nmol/L, P=0.01), TAT (5.28 versus 4.07 mug/L, P lt 0.01), D-dimer ( 443 versus 194 ng/mL, P lt 0.001) and vWF (216 versus 198 IU/dL, P lt 0.05) levels were higher in these patients than in stable/improving patients. In logistic regression analysis, with all important clinical and laboratory variables included, only natural log D-dimer (odds ratio [OR]: 1.87; 95% confidence interval [CI]: 1.38 to 2.54; P=0.0001) and mean arterial blood pressure (OR: 1.26 per 10 mm Hg change; 95% CI: 1.05 to 1.51; P=0.01) remained independent predictors of progressing stroke.</p>
<p><b>Conclusions:</b> There is evidence of excess thrombin generation and fibrin turnover in patients with progressing ischemic stroke. Measurement of D-dimer levels can identify patients at high risk for stroke progression. Further research is required to determine whether such patients benefit from acute interventions aimed at modifying hemostatic function.</p>
Developing and validating a predictive model for stroke progression
<p><b>Background:</b> Progression is believed to be a common and important complication in acute stroke, and has been associated with increased mortality and morbidity. Reliable identification of predictors of early neurological deterioration could potentially benefit routine clinical care. The aim of this study was to identify predictors of early stroke progression using two independent patient cohorts.</p>
<p><b>Methods:</b> Two patient cohorts were used for this study – the first cohort formed the training data set, which included consecutive patients admitted to an urban teaching hospital between 2000 and 2002, and the second cohort formed the test data set, which included patients admitted to the same hospital between 2003 and 2004. A standard definition of stroke progression was used. The first cohort (n = 863) was used to develop the model. Variables that were statistically significant (p < 0.1) on univariate analysis were included in the multivariate model. Logistic regression was the technique employed using backward stepwise regression to drop the least significant variables (p > 0.1) in turn. The second cohort (n = 216) was used to test the performance of the model. The performance of the predictive model was assessed in terms of both calibration and discrimination. Multiple imputation methods were used for dealing with the missing values.</p>
<p><b>Results:</b> Variables shown to be significant predictors of stroke progression were conscious level, history of coronary heart disease, presence of hyperosmolarity, CT lesion, living alone on admission, Oxfordshire Community Stroke Project classification, presence of pyrexia and smoking status. The model appears to have reasonable discriminative properties [the median receiver-operating characteristic curve value was 0.72 (range 0.72–0.73)] and to fit well with the observed data, which is indicated by the high goodness-of-fit p value [the median p value from the Hosmer-Lemeshow test was 0.90 (range 0.50–0.92)].</p>
<p><b>Conclusion:</b> The predictive model developed in this study contains variables that can be easily collected in practice therefore increasing its usability in clinical practice. Using this analysis approach, the discrimination and calibration of the predictive model appear sufficiently high to provide accurate predictions. This study also offers some discussion around the validation of predictive models for wider use in clinical practice.</p>
Quasiperiodic spin-orbit motion and spin tunes in storage rings
We present an in-depth analysis of the concept of spin precession frequency
for integrable orbital motion in storage rings. Spin motion on the periodic
closed orbit of a storage ring can be analyzed in terms of the Floquet theorem
for equations of motion with periodic parameters and a spin precession
frequency emerges in a Floquet exponent as an additional frequency of the
system. To define a spin precession frequency on nonperiodic synchro-betatron
orbits we exploit the important concept of quasiperiodicity. This allows a
generalization of the Floquet theorem so that a spin precession frequency can
be defined in this case too. This frequency appears in a Floquet-like exponent
as an additional frequency in the system in analogy with the case of motion on
the closed orbit. These circumstances lead naturally to the definition of the
uniform precession rate and a definition of spin tune. A spin tune is a uniform
precession rate obtained when certain conditions are fulfilled. Having defined
spin tune we define spin-orbit resonance on synchro--betatron orbits and
examine its consequences. We give conditions for the existence of uniform
precession rates and spin tunes (e.g. where small divisors are controlled by
applying a Diophantine condition) and illustrate the various aspects of our
description with several examples. The formalism also suggests the use of
spectral analysis to ``measure'' spin tune during computer simulations of spin
motion on synchro-betatron orbits.Comment: 62 pages, 1 figure. A slight extension of the published versio
Bubble Shape Oscillations and the Onset of Sonoluminescence
An air bubble trapped in water by an oscillating acoustic field undergoes
either radial or nonspherical pulsations depending on the strength of the
forcing pressure. Two different instability mechanisms (the Rayleigh--Taylor
instability and parametric instability) cause deviations from sphericity.
Distinguishing these mechanisms allows explanation of many features of recent
experiments on sonoluminescence, and suggests methods for finding
sonoluminescence in different parameter regimes.Comment: Phys. Rev. Lett., in pres
The Sound of Sonoluminescence
We consider an air bubble in water under conditions of single bubble
sonoluminescence (SBSL) and evaluate the emitted sound field nonperturbatively
for subsonic gas-liquid interface motion. Sound emission being the dominant
damping mechanism, we also implement the nonperturbative sound damping in the
Rayleigh-Plesset equation for the interface motion. We evaluate numerically the
sound pulse emitted during bubble collapse and compare the nonperturbative and
perturbative results, showing that the usual perturbative description leads to
an overestimate of the maximal surface velocity and maximal sound pressure. The
radius vs. time relation for a full SBSL cycle remains deceptively unaffected.Comment: 25 pages; LaTex and 6 attached ps figure files. Accepted for
publication in Physical Review
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