19 research outputs found
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
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- The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
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- ZZ Chong
- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
Plasma lipid profiles discriminate bacterial from viral infection in febrile children
- Author
- Abdulla A. (Amina)
- Abelake E. (Eugenia)
- Adeel A.O.A. (A. O.A.)
- Aebi C. (Christoph)
- Aebi C. (Christoph)
- Agapow P. (Paul)
- Agbeko R. (Rachel)
- Agyeman P. (Philipp)
- Anderson S. (Suzanne)
- Antonio M. (Martin)
- Baer W. (Walter)
- Barham H. (Heather)
- Barral-Arca R. (Ruth)
- Barrios X.G. (Xavier Gabaldó)
- Bartlett M. (Maeve)
- Baumgart H. (Hinrich)
- Baumgartner M. (Markus)
- Behrends U. (Uta)
- Beiroa A.G. (Andrea Grela)
- Bellos E. (Evangelos)
- Berger C. (Christoph)
- Berger C. (Christoph)
- Bernhard-Stirnemann S. (Sara)
- Biebl A. (Ariane)
- Binder A. (Alexander)
- Birnbacher R. (Robert)
- Blanke J.-G. (Jan-Gerd)
- Boeddha N.P. (Navin)
- Boelke C. (Carsten)
- Bojang K. (Kalifa)
- Bokhandi S. (S.)
- Breukels M.A. (M. A.)
- Breuling K. (Kai)
- Brinkman D.M.C.
- Brunner J. (Jürgen)
- Buller M. (Maria)
- Camuzeaux S. (Stephane)
- Carreras E. (Eduardo)
- Carrol E.D. (Enitan)
- Carter S. (Stephanie)
- Cebey-López M. (Miriam)
- Coin L.M.J. (Lachlan M. J.)
- Cole F. (Fatoumata)
- Contreras J.R. (J. Ruiz)
- Cooke E.F. (Elizabeth Fernández)
- Crate L. (Lindsey)
- Curras-Tuala M.J. (María José)
- Dahlem P. (Peter)
- Davies P. (P.)
- de Korte C.C.M.M. (C. C.M.M.)
- de Vries E. (E.)
- Deep A. (Akash)
- Dekkers R. (R.)
- Deuren M. (Marcel) van
- Dietrich B. (Beate)
- Dings-Lammertink A. (A.)
- Doedens R.A. (R. A.)
- Donker A.E. (A.)
- Dousma M. (M.)
- Driessen G.J.A. (Gertjan)
- Eber E. (Ernst)
- Eleftherohorinou H. (Hariklia)
- Elias J. (Johannes)
- Ellacuriagal A.S. (Antonio Salas)
- Emhofer J. (Josef)
- Emonts M. (Marieke)
- Emonts M. (Marieke)
- Ende A. (A.) van der
- Etschmaier R. (Rosa)
- Faber T.E. (T. E.)
- Farr S. (Sebastian)
- Faust D. (Dominik)
- Fernández R. (Reyes)
- Fernández S.S. (Sonia Serén)
- Fink C. (Colin)
- Flier M. (Michiel) van der
- Forte M.S. (Miguel Sánchez)
- Fortune P.M. (P. M.)
- Frederick H. (Hannah)
- Galassini R. (Rachel)
- García N. (Natalia)
- Gerrit G.P.J.M. (Gerardus)
- Gerver J.A.M. (J. A.M.)
- Giannoni P.
- Girtler Y. (Ylenia)
- González F.Á. (Fernando Álvez)
- Gormley S. (Stuart)
- Grande A.J. (Antonio Justicia)
- Gribbin A. (Andrew)
- Grigorow I. (Irina)
- Groot R. (Ronald) de
- Guillén S. (Sara)
- Gutiérrez B.M. (Beatriz Morillo)
- Gómez-Carballa A. (Alberto)
- Hamilton S. (Shea)
- Hardy K. (Katie)
- Hasters P. (Paul)
- Hazelzet J.A. (Jan)
- Heidema J. (Jojanneke)
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- Heininger U. (Ulrich)
- Herberg J.A. (Jethro A.)
- Hoggart C. (Clive)
- Hourmat B. (Bernardo)
- Hudnott P. (Phil)
- Ibarrondo C.E. (Cristina Epalza)
- Iglesias P.L. (Pilar Leboráns)
- Ihm U. (Ulrike)
- Inwald D. (David)
- Jackson H. (Heather)
- Jacobs M.A.M. (M. A.M.)
- Jansen N.J.G. (N. J.G.)
- Jaros Z. (Zdenek)
- Jennings R. (Rebecca)
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- Kaforou M. (Myrsini)
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- Kaulfersch W. (Wilhelm)
- Kawczynski P. (P.)
- Kebbeh N. (Ngange)
- Kemen C. (Christoph)
- Kenwright R. (Rhian)
- khan S. (Saidy)
- Klobassa D.S. (Daniela S.)
- Klocker N. (Nina)
- Klucovska K. (K.)
- Kneyber M.C.J. (M. C.J.)
- Kohlmaier B. (Benno)
- Komini E. (Eleni)
- Koopman-Keemink Y. (Yvonne)
- Kramer L. (Lydia)
- Kuijpers T.T. (Taco T.)
- Köster B. (Bernhard)
- Langenhorst V.J. (V. J.)
- Leusink J. (J.)
- Levin M. (Michael)
- Lewis M.R. (Matthew R.)
- León M.C.L. (María Cruz León)
- Loza B.F. (Bettina F.)
- Lozano M.J. (María José)
- MacOnochie I.K. (Ian)
- Martinon-Torres F. (Federico)
- Martinón-Torres F. (Federico)
- MartinónTorres N. (Nazareth)
- Mashbat M. (Meg)
- McClure M. (Myra)
- McCorkell J. (Jenni)
- McCready S. (Sharon)
- Menikou S. (Stefanie)
- Merth I.T. (I. T.)
- Miedema C.J. (C. J.)
- Mingorance Á.N. (Álvaro Navarro)
- Momodou ()
- Moreno D. (David)
- Mustafa S. (Sobia)
- Nadel S. (Simon)
- Navarra H. (Helen)
- Navarro M. (Marisa)
- Neeleman C. (C.)
- Neth O. (Olaf)
- Neubert A. (Antje)
- Niederer-Loher A. (Anita)
- Nijman R.G. (Ruud)
- Noordzij J.G. (Jeroen)
- Nsirim E. (Eniola)
- Obihara C.C. (Charlie C.)
- Ortner D. (Daniel)
- O’Neill L. (Lauren)
- Pacheco P.O. (Pablo Obando)
- Padilla M.C.M. (Ma del Carmen Martínez)
- Pajkrt D. (D.)
- Palacios A. (Alba)
- Pardo-Seco J. (Jacobo)
- Patel R. (Rekha)
- Patel S.Y. (Smita Y.)
- Pathan D.N. (Dr N)
- Paulus S.C. (Stephane C.)
- Pescollderungg L. (Lydia)
- Peters M. (Mark)
- Pfurtscheller K. (Klaus)
- Philipsen H.L.A. (H. L.A.)
- Pinnock E. (Elli)
- Pischedda S. (Sara)
- Pollard A.J. (Andrew J.)
- Poortman G.H. (G. H.)
- Posfay-Barbe K.M. (Klara M.)
- Potgieter S.T. (S. T.)
- Potjewijd J. (J.)
- Power S. (Sue)
- Pérez B.M. (Belén Mosquera)
- Rahman R. (Rahmeen)
- Ramaiah R. (R.)
- Redondo-Collazo L. (Lorenzo)
- Reiter K. (Karl)
- Relly C. (Christa)
- Reyes S.B. (Susana Beatriz)
- Rial J.G. (Jose Gómez)
- Ridout J. (Jenna)
- Ristic G. (Goran)
- RiveroCalle I. (Irene)
- Rodríguez-Tenreiro C. (Carmen)
- Rojo P. (Pablo)
- Rosias P.P.R. (Philippe)
- Royad C. (C.)
- Rödl S. (Siegfried)
- Sagmeister M. (Manfred)
- Salas A. (Antonio)
- Sanagustín S.B. (Sonia Brió)
- Sancho-Shimizu V. (Vanessa)
- Sanders E.A.M. (E. A.M.)
- Sands C. (Caroline)
- Santos A.E.M. (Alba Elena Martínez)
- Sarr I. (Isatou)
- Schlapbach L.J. (Luregn)
- Schweintzger N.A. (Nina A.)
- Secka F. (Fatou)
- Sellner A. (Andrea)
- Sey G. (Gibbi)
- Silva M.S.P. (María del Sol Porto)
- Silveira L.F. (Laura Fernández)
- Sonnleitner A. (Astrid)
- Sperl M. (Matthias)
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- Standing F. (Fran)
- Stelzl W. (Wolfgang)
- Stocker M. (Martin)
- Sánchez F.G. (Francisco Giménez)
- Sánchez J.M.M. (José María Martinón)
- Tato L.M.P. (Luis Manuel Prieto)
- ten Tussher G.W. (G. W.)
- Thakker C. (Clare)
- Thio B.J. (B. J.)
- Thomas G. (Gilleh)
- Thurston S. (Sarah)
- Till H. (Holger)
- Torre A.C. (Andrés Concha)
- Tramper-Stranders G.A. (Gerdien)
- Trillo L.V. (Lucía Vilanova)
- Trobisch A. (Andreas)
- Tuffrey C. (Catherine)
- van de Beek D. (D.)
- van der Meer H. (H.)
- van Furth A.M.T. (A. M. Tutu)
- van Kuppevelt A.J.M. (A. J.M.)
- van Overbeek – van Gils A.L.T. (A. L.T.)
- van Wermeskerken A.M. (A. M.)
- Veen J.H.-V. (J. Homan-van der)
- Vega A. (Ana)
- Vergara E.O. (Eider Oñate)
- Verwijs W.A. (W. A.)
- Vicente L.G. (Luisa García)
- Vierzig A. (Anne)
- Vivanco A. (Ana)
- Vogel U. (Ulrich)
- Waal W.J. (Wouter) de
- Wang X. (Xinzhu)
- Weingarten C. (Christina)
- Welke S. (Stefanie)
- White D. (Deborah)
- White S. (Sonia)
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- Wimmer A. (Andreas)
- Wintergerst U. (Uwe)
- Wolfs T.F.W. (T. F.W.)
- Wright V.J. (Victoria)
- Wüller D. (Daniel)
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- Zaunschirm A. (Andrew)
- Zenz W. (Werner)
- Ziuraite I. (Ieva)
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- Žukovskaja V. (Veslava)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2019
- Field of study
Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar
Samenstelling en redactie van het tijdschrift 'Feuilles de Documentation du Professeur de Géographie', M. Barbé, Comines, 11 nummers.
- Publication venue
- Publication date
- Field of study
Summary of Reading Investigations July 1, 1951 to June 30, 1952
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- Allen M. Robert
- Ballantine Francis A.
- Barbe Walter
- Barbe Walter
- Barbe Walter
- Bish Charles E.
- Black Elsie Benson.
- Blanchard B. Everard
- Bond George W.
- Colvin Cynthia M.
- Davis Frederick B.
- Delacato Janice F.
- Dixon W. Robert
- Fabian Abraham A.
- Farr James N.
- Flesch Rudolph
- Gerberich J. Raymond
- Gesselman Daisy B.
- Gray William S.
- Gray William S.
- Johnson Mary E.
- Ketcham Warren A.
- Klare George
- Lauer Jeanne
- Lyness Paul I.
- Lyness Paul I.
- Maclatchy Josephine H.
- MacLean Malcolm S.
- Morse William S.
- Nafziger Ralph O.
- Oaks Ruth E.
- Preston Ralph C.
- Raths Louis E.
- Schramm Wilbur
- Sheldon William D.
- Traxler Arthur
- William S. Gray
- Witty Paul
- Witty Paul
- Witty Paul
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Art for the Gifted and Talented Child
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Macrophage Populations in Different Stages of Induced Hepatic Metastases in Rats: an Immunohistochemical Analysis
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Summary of Reading Investigations July 1, 1957 to June 30, 1958
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- Ahmann J.
- Asheim Lester
- Barbe Walter B.
- Barbe Walter B.
- Bevington W. G.
- Bishton Rodger.
- Blanchard B. Everard.
- Bolling Rexford W.
- Boykin Leander L.
- Bremer Neville.
- Burroughs G. E. R.
- Chall Jeanne S.
- Chall Jeanne S.
- Chansky Norman M.
- Chansky Norman M.
- Chase W. Linwood
- Collier Mary J.
- Cooper William Hickerson.
- Crook Frances E.
- Curry John Foster.
- De Boer John J.
- Deverell A. F.
- Dilley N. E.
- Duggins Lydia A.
- Dumler Marvin J.
- Durrell Donald D.
- Early Margaret J.
- Felton Wilma.
- Fridian Sister M.
- Gleason Gerald T.
- Goins Jean Turner.
- Gray William S.
- Himmler Merwin L.
- Holmes Jack A.
- Humphry Kenneth H.
- Hunt Lyman C.
- Jewett Arno.
- Johnson Marjorie Seddon.
- Karlin Robert.
- Karlin Robert.
- Kelly Barbara Cline.
- Kingsley Marjorie.
- Klare George R.
- Krantz L. L.
- Lee W. R.
- Manolakes George.
- Mathewson Angell
- McCullough Constance M.
- McCullough Constance M.
- Mills Mary.
- Murphy Helen A.
- Olson Willard.
- Purcell Barbara A.
- Queensland Education Department Reading Methods for Queensland Infants’ Schools
- Reeve Olive R.
- Roberts Richard W.
- Rose Florence C.
- Sarbaugh L. E.
- Schmidt W. H. O.
- Sekerak Robert M.
- Smith Nila B.
- Staiger Ralph C.
- Tinker Miles A.
- Todd Kermit R.
- Traxler Arthur E.
- Triggs Frances Oralind.
- Turner Mary Alice.
- Weisgerber S. J.
- William S. Gray
- Wollner Mary H. B.
- Wyatt Nita M.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study
- Author
- Anttalainen U.
- Anttalainen Ulla
- Barbe F.
- Basoglu O. K.
- Basoglu Ozen K.
- Bielicki P.
- Bonsignore M. R.
- Bonsignore Maria R.
- Bouloukaki I.
- Dogas Z.
- Drummond M.
- Escourrou P.
- Fietze I.
- Galic T.
- Grote L.
- Grote Ludger
- Hedner J.
- Hedner Jan
- Hein H.
- Joppa P.
- Kent B.
- Kvamme J. A.
- Lavie L.
- Lavie P.
- Levy P.
- Lombardi C.
- Ludka O.
- Ludka Ondrej
- Marrone O.
- Masa J. F.
- McNicholas W. T.
- McNicholas Walter T.
- Montserrat J. M.
- Parati G.
- Pataka A.
- Pataka Athanasia
- Penzel T.
- Pepin J-L.
- Pepin Jean-Louis
- Petiet E.
- Plywaczewski R.
- Pretl M.
- Riha R. L.
- Riha Renata L.
- Rodenstein D.
- Roisman G.
- Ryan S.
- Ryan Silke
- Saaresranta T.
- Safarik P. J.
- Schiza S.
- Schiza Sofia
- Schulz R.
- Sliwinski P.
- Sliwinski Pawel
- Staats R.
- Steiropoulos P.
- Steiropoulos Paschalis
- Tasbakan M. S.
- Tkacova R.
- Trakada G.
- van Zeller M.
- Varoneckas G.
- Verbraecken Johan
- Vitols A.
- Publication venue
- Publication date
- 01/01/2019
- Field of study
###EgeUn###European Union COST action [B26]; European Respiratory Society; ResMed; Philips Respironics Foundation; European Sleep Research SocietyThe ESADA network has received support from the European Union COST action B26 and is currently a Clinical Research Collaboration funded by the European Respiratory Society. Additionally, the ESADA study group has received unrestricted seeding grants from the ResMed and the Philips Respironics Foundation for the establishment of the database in 2007 and 2011. The ESADA has an ongoing collaboration with Bayer AG. Non-financial support was provided by the European Sleep Research Society and the European Respiratory Society for communication, meetings and data presentations for the ESADA collaborators