Photo-induced curing of thymine-based bioinspired polymers. A chemometric analysis

The curing process of new materials based on styrene monomers functionalized with thymine and charged ionic groups was studied using UV-vis spectroscopy in combination with chemomet-ric models. The effect of the copolymer molecular weight on the immobilization point was analyzed. The evolution of the curing process of the copolymer (4-vinylbenzyl) thymine (VBT) -vinylbenzyl triethyl ammonium chloride (VBA) involved three species, which absorb in the spectral region analyzed. The contributions of each species to the total signal at each irradiation time were determined, and the ki-netic constant of the crosslinking reaction was esti-mated. The study allowed evaluating the consistency of the chemometric decomposition, obtaining a rea-sonable correlation between the frequency spectra and the time evolution calculated with the algorithm. The chemometric analysis showed to be a powerful tool to provide complementary information on photo-induced immobilization of VBT-VBA films, which is crucial for developing new environmentally benign materials and new energy-saving methods.Fil: Bortolato, Santiago Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Salta. Instituto de Investigación para la Industria Química (i); ArgentinaFil: Barbarini, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Salta. Instituto de Investigación para la Industria Química (i); ArgentinaFil: Benitez, R. M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Salta. Instituto de Investigación para la Industria Química (i); ArgentinaFil: Martino, Debora Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Salta. Instituto de Investigación para la Industria Química (i); ArgentinaFil: Estenoz, Diana Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Salta. Instituto de Investigación para la Industria Química (i); Argentin

Crosslinkable micelles from diblock amphiphilic copolymers based on vinylbenzyl thymine and vinylbenzyl triethylammonium chloride

Polymeric micelles (PMs) composed of self-assembled amphiphilic block copolymers were synthesized from vinylbenzyl thymine (VBT) and vinylbenzyl triethylammonium chloride (VBA) exhibiting improved physical stability. Three diblock copolymers of different chemical compositions and similar molecular weights (polydispersities below 1.5) were obtained via nitroxide mediated radical polymerization. Critical micelle concentration (CMC) was determined by dye micellization method, the shift of the absorption peak of the anionic (EY) due to the interactions with non-assembled chains and auto-assembled copolymers was followed. Polymeric systems exhibited good stability revealing that a higher proportion of cationic monomers in the diblock reduce the CMC. Furthermore,after the core of PMs was photocrosslinked by UV irradiation, the CMC decreases notably. Kinetic release studies using EY dye as probe demonstrated that both, higher VBA ratios in the polymer and higher UV-irradiation, slow down the dye release.Fil: Barbarini, Alejandro Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Física del Litoral; ArgentinaFil: Estenoz, Diana Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico Para la Industria Química (i); ArgentinaFil: Martino, Debora Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Física del Litoral; Argentin