1 research outputs found
Nanoparticle-Assisted NMR Detection of Organic Anions: From Chemosensing to Chromatography
Monolayer-protected nanoparticles
provide a straightforward access
to self-organized receptors that selectively bind different substrates
in water. Molecules featuring different kinds of noncovalent interactions
(namely, hydrophobic, ion pairing, and metal–ligand coordination)
can be grafted on the nanoparticle surface to provide tailored binding
sites for virtually any class of substrate. Not only the selectivity
but also the strength of these interactions can be modulated. Such
recognition ability can be exploited with new sensing protocols, based
on NMR magnetization transfer and diffusion-ordered spectroscopy (DOSY),
to detect and identify organic molecules in complex mixtures