Automating Workflow: From a Trickle to a Stream

Ideally, bulking up an institutional repository with a full listing of faculty publications is a worthy goal, but how can that be accomplished within a reasonable time period? Cleveland State University implemented Digital Commons in March 2012 with the KickStart program. Since then, faculty publications have been added at a steady, but slow pace. Through a collaborative effort, our Digital Initiatives Librarian worked with others to refine batch processing to increase the flow of record creation and document loading into EngagedScholarship@CSU. With the use of Excel, scripts, faculty CVs and Google Drive, the staff is finding new ways to automate the process of populating our IR. This presentation will discuss the technical components that move the process along and the personnel components that make this process work. CSU is also exploring the use of bibliographic information reported from Faculty Annual Activity Reports (FAAR) to capture current faculty scholarly activities

Meeting the Accessiblity Standards for Digital Content at CSU

Presentation to the Ohio Digitization Interest Group on Cleveland State University’s Michael Schwartz Library workflows for processing files to meet the accessibility standards

Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome

Proteomics techniques for analysing the redox status of individual proteins in complex mixtures tend to identify the same proteins due to their high abundance. We describe here an array-based technique to identify proteins undergoing glutathionylation and apply it to the secretome and the proteome of human monocytic cells. The method is based on incorporation of biotinylated glutathione (GSH) into proteins, which can then be identified following binding to a 1000-protein antibody array. We thus identify 38 secreted and 55 intracellular glutathionylated proteins, most of which are novel candidates for glutathionylation. Two of the proteins identified in these experiments, IL-1 sRII and Lyn, were then confirmed to be susceptible to glutathionylation. Comparison of the redox array with conventional proteomic methods confirmed that the redox array is much more sensitive, and can be performed using more than 100-fold less protein than is required for methods based on mass spectrometry. The identification of novel targets of glutathionylation, particularly in the secretome where the protein concentration is much lower, shows that redox arrays can overcome some of the limitations of established redox proteomics techniques

Developing an Open Educational Resource: Leading Campus OER Initiatives through Library-Faculty Collaboration

Open Educational Resources (OERs) are gaining traction as students and faculty search for affordable, open access alternatives for learning resources. Find out how one public university library took advantage of the push for OERs and enthusiasm after a library-sponsored OER workshop to publish an open access textbook. This presentation will describe the library’s involvement in developing the project, balancing the workload between librarians and the faculty member, and promoting the new resource on campus. Key takeaways include the importance of communicating, dealing with permissions, taking advantage of graphic design skills, and more. Attendees will leave with ideas about how to implement a similar project at their own institutions

Developing an Open Educational Resource: Leading Campus OER Initiatives through Library-Faculty Collaboration

Open Educational Resources (OERs) are gaining traction as students and faculty search for affordable, open access alternatives for learning resources. Find out how one public university library took advantage of the push for OERs and enthusiasm after a library-sponsored OER workshop to publish an open access textbook. This presentation will describe the library’s involvement in developing the project, balancing the workload between librarians and the faculty member, and promoting the new resource on campus. Key takeaways include the importance of communicating, dealing with permissions, taking advantage of graphic design skills, and more. Attendees will leave with ideas about how to implement a similar project at their own institutions

Scholarly Communications: Ask the Experts

Do you have questions about how the library can support scholarly communications? Learn what EngagedScholarship @ Cleveland State University can do for you including publishing journals or books; posting articles; creating your own Scholars Page; learning about copyright; managing conferences or ongoing meetings, and more. Ask our experts, Marsha Miles, Head of Collections and Digital Initiatives; Mandi Goodsett, Performing Arts & Humanities Librarian, OER & Copyright Advisor; and Barbara Loomis, Digital Scholarly Publications and Programs Administrator. Complete the registration form at https://forms.gle/pBMqNXDJEyiDsg819 to be emailed the Zoom link on the day of the event. For more information visit the EngagedScholarship @ CSU Research Guide at http://researchguides.csuohio.edu/EngagedScholarshi

The More We Work Together: Leading Campus OER Initiatives through Library-Faculty Collaboration

With the rising costs of tuition and textbooks, Open Educational Resources (OERs) are becoming increasingly important. The university library, in collaboration with faculty, is a natural leader of OER initiatives at institutions of higher education. Cleveland State University’s Michael Schwartz Library embraced this leadership role by assisting a faculty member with developing an OER, which involved balancing the workload between librarians and the faculty member, determining successful modes of communication, taking advantage of graphic design skills, and more. The success of this initial collaboration has led the Library to expand its support of OER initiatives on campus

Cleveland State Taps into Faculty and Campus Needs

At Cleveland State University, the library collaborates with faculty and departments on projects such as: capturing and sharing conferences; publishing scholarly journals; and creating and disseminating open educational resources. These endeavors have led to additional opportunities in other areas, such as working with students and with the greater Cleveland community. In this webinar, Barbara Loomis, Project Coordinator, Marsha Miles, Digital Initiatives Librarian, and Theresa Nawalaniec, Sciences and Engineering Librarian, at Cleveland State’s Michael Schwartz Library will discuss their work with faculty and departments and the other projects that these have often led to

Gradual Shutdown of Virus Production Resulting in Latency Is the Norm during the Chronic Phase of Human Immunodeficiency Virus Replication and Differential Rates and Mechanisms of Shutdown Are Determined by Viral Sequences

AbstractMost CD4+lymphocytes in lymph nodes of both asymptomatic HIV-1-infected individuals and AIDS patients are nonproductively or latently infected. It is not clear how these cells come about because infection of resting lymphocytes results in abortive infection and infection of activated lymphocytes results in productive infection. The frequency and mechanisms underlying nonproductive or latent HIV infections of normal CD4+lymphocytes largely remain unexplored, and because HIV latency has principally been studied in latently infected cell clones of established cell lines, it is not even clear how often this type of infection occurs in cell lines. We demonstrate herein that chronic HIV replication in populations of normal phytohemagglutinin-stimulated peripheral blood CD4+-enriched lymphocytes, as well as an established T-cell line (CEM), gradually shuts down in the vast majority of cells. The nonproducing cells in these cultures still harbored HIV provirus, and HIV could be reactivated in CEM cells by treatment with phorbol ester, showing that this was latent infection. Thus, HIV's life cycle should probably be considered as consisting of two phases: an acute exponential rise in production of virus progeny which levels at some peak, followed by a gradual decline of progeny production during the chronic phase leading to viral latency. Temporal analyses of the steady-state levels of viral mRNAs in populations of chronically infected CEM cells as virus production declined revealed the two mechanisms of HIV latency which have previously been described in the OM-10.1 and U1 or ACH-2 latently infected cell clones (i.e., apparent overall shutdown of HIV transcription and “blocked early-stage latency” involving enhanced splicing of viral pre-mRNAs). However, which mechanism was employed, as well as the rate of shutdown, depended on the virus strain

Development of a Questionnaire for Use in Extension Program Planning

Family Relations and Child Developmen