SDSS-IV MaNGA: The Roles of AGNs and Dynamical Processes in Star Formation Quenching in Nearby Disk Galaxies

We study how star formation (SF) is quenched in low-redshift disk galaxies with integral-field spectroscopy. We select 131 face-on spiral galaxies with stellar mass greater than $\rm 3\times10^{10}M_\odot$, and with spatially resolved spectrum from MaNGA DR13. We subdivide the sample into four groups based on the offset of their global specific star formation rate (SFR) from the star-forming main sequence and stack the radial profiles of stellar mass and SFR. By comparing the stacked profiles of quiescent and star-forming disk galaxies, we find that the decrease of the global SFR is caused by the suppression of SF at all radii, but with a more significant drop from the center to the outer regions following an inside-out pattern. As the global specific SFR decreases, the central stellar mass, the fraction of disk galaxies hosting stellar bars, and active galactic nuclei (AGNs; including both LINERs and Seyferts) all increase, indicating dynamical processes and AGN feedback are possible contributors to the inside-out quenching of SF in the local universe. However, if we include only Seyferts, or AGNs with ${\rm EW(H\alpha)>3\AA}$, the increasing trend of AGN fraction with decreasing global sSFR disappears. Therefore, if AGN feedback is contributing to quenching, we suspect that it operates in the low-luminosity AGN mode, as indicated by the increasing large bulge mass of the more passive disk galaxies.Comment: 12 pages, 7 figures, published in ApJ, typos corrected, references update

Time-lapse Whole-field fluorescence imaging of microglia processes motility in acute mouse hippocampal slices and analysis

Microglia are the resident immune cells of the central nervous system (CNS). In the last year, the improvements in the transgenic mouse technologies and imaging techniques have shed light on microglia functions under physiological conditions. Microglia continuously scan the brain parenchyma with their highly motile processes, maintaining tissue homeostasis and participating in neuronal circuits refinement. Here, we describe a protocol that enables us to perform time-lapse imaging of microglial cells in acute hippocampal slices, making image acquisition possible on an electrophysiology rig equipped with a standard imaging system. Using this ex vivo approach, we investigated microglial processes scanning abilities under physiological condition in hippocampus

Superhydrophobicity Due to the Hierarchical Scale Roughness of PDMS Surfaces

Wettability control has been widely investigated in the last decades for technological applications such as microfluidic devices and self-cleaning surfaces by modifying both the chemical composition and the geometric structure of the surfaces. Inspired by the typical morphology of superhydrophobic leaves (such as lotus leaves), we have developed a dual-scale roughness, micro- and nanosized, on polydimethylsiloxane (PDMS) surfaces. By combining different geometric parameters and plasma treatment conditions, the structures were controlled hierarchically, at different independent length scales. Both the microsized replicated pillars and the nanosized etched posts tuned the wettability of the PDMS surfaces in a very simple way, up to contact angles of 170°. Furthermore, changes in the influence of micro- and nanoscale geometrical structures were investigated. Hysteresis and contact angles of water droplets are evaluated as a combined effect of micropillars and a superimposed roughness, resulting in high advan..

Engineering transfer of micro- and nanometer-scale features by surface energy modification.

Micropatterning of surfaces is gaining importance in various applications ranging from biosensors to microfluidic and lab-on-a-chip devices, where the control of the surface chemistry is of great importance for the application. In this paper, we introduce a patterning technique of topographical features, which is applicable on different substrates by modifying their surface energy. The textured surface is obtained via polydimethylsiloxane (PDMS) transfer, and the topographical parameters can be systematically tailored by selective treatment with oxygen plasma of either the PDMS stamp, the substrate, or both. Our approach is an alternative technique to create micro- and nanopatterns of various height and shape over a large area on different substrates. The possibility to control cell behavior on different surfaces tailored with this microtransfer patterning approach was also evaluated. The cell culture on patterned surfaces showed the possibility of modulating cell adhesion. Our method is based on simple transfer of silicone elastomeric patterns to the surface, and therefore, it is very simple and fast compared to other complex techniques. These observations could have implications for tissue-scaffold engineering science in areas such as microfluidic devices and control of cell adhesion