Characterization and Testing of the Passive Magnetic Attitude Control System for the 3U AstroBio CubeSat

AstroBio CubeSat is a mission funded by the Italian Space Agency aimed at validating novel lab-on-chip technology, that would enable the use of micro- and nanosatellites as autonomous orbiting laboratories for research in astrobiology. This 3U CubeSat is equipped with a passive magnetic attitude control system (PMACS), including permanent magnets and hysteresis strips, which allows for stabilizing the spacecraft with the longitudinal axis in the direction of the geomagnetic field vector. This work presents the process followed for the experimental characterization of the system, performed on the engineering unit of the satellite by using a Helmholtz cage facility and a spherical air-bearing to recreate environmental conditions similar to the ones experienced during the orbital motion. The hysteresis strips are characterized starting from the determination of the hysteresis loop, from which the energy dissipation per cycle and the apparent magnetic permeability are extracted. Tests performed by using the Helmholtz cage and the air-bearing facility allows for further investigating the damping torque produced by the PMACS and validating the abovementioned parameters. Numerical analysis is then used to select the number of permanent magnets which allows for achieving a pointing accuracy within an error of 10° within 24 h from the deployment. The analysis of the flight data supports the results obtained from the experimental test campaigns, confirming the effectiveness of the proposed methods and of the PMACS design

AstroBio-CubeSat: A lab-in-space for chemiluminescence-based astrobiology experiments

: Space exploration is facing a new era in view of the planned missions to the Moon and Mars. The development and the in-flight validation of new technologies, including analytical and diagnostic platforms, is pivotal for exploring and inhabiting these extreme environments. In this context, biosensors and lab-on-chip devices can play an important role in many situations, such as the analysis of biological samples for assessing the impact of deep space conditions on man and other biological systems, environmental and food safety monitoring, and the search of molecular indicators of past or present life in extra-terrestrial environments. Small satellites such as CubeSats are nowadays increasingly exploited as fast and low-cost platforms for conducting in-flight technology validation. Herein, we report the development of a fully autonomous lab-on-chip platform for performing chemiluminescence-based bioassays in space. The device was designed to be hosted onboard the AstroBio CubeSat nanosatellite, with the aim of conducting its in-flight validation and evaluating the stability of (bio)molecules required for bioassays in a challenging radiation environment. An origami-like microfluidic paper-based analytical format allowed preloading all the reagents in the dried form on the paper substrate, thus simplifying device design and analytical protocols, facilitating autonomous assay execution, and enhancing the stability of reagents. The chosen approach should constitute the first step to implement a mature technology with the aim to conduct life science research in space (e.g., for evaluation the effect of deep space conditions on living organisms or searching molecular evidence of life) more easily and at lower cost than previously possible

Stress neuropeptide levels in adults with chest pain due to coronary artery disease: potential implications for clinical assessment

: Substance P (SP) and neuropeptide Y (NPY) are neuropeptides involved in nociception. The study of biochemical markers of pain in communicating critically ill coronary patients may provide insight for pain assessment and management in critical care. Purpose of the study was to to explore potential associations between plasma neuropeptide levels and reported pain intensity in coronary critical care adults, in order to test the reliability of SP measurements for objective pain assessment in critical care