430 research outputs found

    Study of Pseudo BL–Algebras in View of Left Boolean Lifting Property

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    In this paper, we define left Boolean lifting property (right Boolean lifting property) LBLP (RBLP) for pseudo BL–algebra which is the property that all Boolean elements can be lifted modulo every left filter (right filter) and next, we study pseudo BL-algebra with LBLP (RBLP). We show that Quasi local, local and hyper Archimedean pseudo BL–algebra that have LBLP (RBLP) has an interesting behavior in direct products. LBLP (RBLP) provides an important representation theorem for semi local and maximal pseudo BL–algebra

    Surface roughness and wettability of wool fabrics loaded with silver nanoparticles: Influence of synthesis and application methods

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    Hydrophilization of wool fabrics was performed by silver nanoparticles with different surface charge using three different methods: exhausting, pad–dry–cure and in situ synthesis. Dynamic wetting measurements and surface topography analysis were used to evaluate surface changes on wool fabrics. The wool samples in situ loaded revealed the highest fabric roughness and porosity, while the use of the pad–dry–cure method leads to the lowest fabric porosity, and its roughness values approximately were the same as those for samples loaded with the exhaustion method. The results revealed that loading silver nanoparticles with high surface charges onto wool fabrics via the exhaustion method can significantly improve the hydrophilicity of wool fibre surface. The possible reasons for this improvement are discussed

    Thermal Properties of the Binary-Filler Composites with Few-Layer Graphene and Copper Nanoparticles

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    The thermal properties of an epoxy-based binary composites comprised of graphene and copper nanoparticles are reported. It is found that the "synergistic" filler effect, revealed as a strong enhancement of the thermal conductivity of composites with the size-dissimilar fillers, has a well-defined filler loading threshold. The thermal conductivity of composites with a moderate graphene concentration of ~15 wt% exhibits an abrupt increase as the loading of copper nanoparticles approaches ~40 wt%, followed by saturation. The effect is attributed to intercalation of spherical copper nanoparticles between the large graphene flakes, resulting in formation of the highly thermally conductive percolation network. In contrast, in composites with a high graphene concentration, ~40 wt%, the thermal conductivity increases linearly with addition of copper nanoparticles. The electrical percolation is observed at low graphene loading, less than 7 wt.%, owing to the large aspect ratio of graphene. At all concentrations of the fillers, below and above the electrical percolation threshold, the thermal transport is dominated by phonons. The obtained results shed light on the interaction between graphene fillers and copper nanoparticles in the composites and demonstrate potential of such hybrid epoxy composites for practical applications in thermal interface materials and adhesives.Comment: 25 pages, 4 figure

    Association of GSTP1 gene polymorphisms with performance traits in Deoni cattle

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    Heat stress directly and indirectly stimulate excessive intra/inter cellular toxicants such as malondialdehyde (MDA) and reactive oxygen species (ROS). Glutathione S-transferase Pi (GSTP1) plays the central role in the detoxification of ROS. In this investigation, we studied the genetic variation in GSTP1 gene using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique in 70 Deoni breed cows. All the seven exons of GSTP1 gene were amplified by PCR using a total of six sets of primers. The genetic variants were determined by PCR-SSCP technique. Two unique SSCP patterns were observed in fragment 1, 3, 5 and 6 of GSTP1 gene. Sequence analysis with reference to GenBank Acc. no AC_000186.1 revealed polymorphisms at position 210, 746, 2438, 2439, 2443, 2507, 2695 and insertions between positions 707 and 708, 2700-2701 and 2775-2776. All the observed variations in coding regions were silent mutations. The cows with SSCP pattern B of fragment-5 had higher age at first calving while the cows with pattern A had higher lactation length and lactation yield as compared to pattern B (P≤0.05). The animals with pattern A of fragment 6 in GSTP1 gene had higher lactation length and lactation yield as compared to animals with pattern B. There was no significant difference in enzyme activity and calving interval in cows with different patterns in different SSCP fragments.Keywords: Deoni, GSTP1, polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP), single nucleotide polymorphism (SNP), heat stressAfrican Journal of Biotechnology Vol. 12(24), pp. 3768-377

    Numerical and experimental analysis of a hybrid material acoustophoretic device for manipulation of microparticles.

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    Acoustophoretic microfluidic devices have been developed for accurate, label-free, contactless, and non-invasive manipulation of bioparticles in different biofluids. However, their widespread application is limited due to the need for the use of high quality microchannels made of materials with high specific acoustic impedances relative to the fluid (e.g., silicon or glass with small damping coefficient), manufactured by complex and expensive microfabrication processes. Soft polymers with a lower fabrication cost have been introduced to address the challenges of silicon- or glass-based acoustophoretic microfluidic systems. However, due to their small acoustic impedance, their efficacy for particle manipulation is shown to be limited. Here, we developed a new acoustophoretic microfluid system fabricated by a hybrid sound-hard (aluminum) and sound-soft (polydimethylsiloxane polymer) material. The performance of this hybrid device for manipulation of bead particles and cells was compared to the acoustophoretic devices made of acoustically hard materials. The results show that particles and cells in the hybrid material microchannel travel to a nodal plane with a much smaller energy density than conventional acoustic-hard devices but greater than polymeric microfluidic chips. Against conventional acoustic-hard chips, the nodal line in the hybrid microchannel could be easily tuned to be placed in an off-center position by changing the frequency, effective for particle separation from a host fluid in parallel flow stream models. It is also shown that the hybrid acoustophoretic device deals with smaller temperature rise which is safer for the actuation of bioparticles. This new device eliminates the limitations of each sound-soft and sound-hard materials in terms of cost, adjusting the position of nodal plane, temperature rise, fragility, production cost and disposability, making it desirable for developing the next generation of economically viable acoustophoretic products for ultrasound particle manipulation in bioengineering applications

    Oil-in-water microemulsion encapsulation of antagonist drugs prevents renal ischemia-reperfusion injury in rats

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    Developing new therapeutic drugs to prevent ischemia/reperfusion (I/R)-induced renal injuries is highly pursued. Liposomal encapsulation of spironolactone (SP) as a mineralocorticoid antagonist increases dissolution rate, bioavailability and prevents the drug from degradation. In this context, this work develops a new formulation of oil-in-water type microemulsions to enhance the bioavailability of SP. The size of the SP-loaded microemulsion was about 6.0 nm by dynamic light scattering analysis. Briefly, we investigated the effects of nano-encapsulated SP (NESP) on renal oxidative stress, biochemical markers and histopathological changes in a rat model of renal I/R injury. Forty eight male Wistar rats were divided into six groups. Two groups served as control and injury model (I/R). Two groups received “conventional” SP administration (20 mg/kg) and NESP (20 mg/kg), respectively, for two days. The remaining two groups received SP (20 mg/kg) and NESP (20 mg/kg) two days before induction of I/R. At the end of the experiments, serum and kidneys of rats underwent biochemical, molecular and histological examinations. Our results showed that I/R induces renal oxidative stress, abnormal histological features and altered levels of renal biomarkers. Administration of SP in healthy animals did not cause any significant changes in the measured biochemical and histological parameters compared to the control group. However, SP administration in the I/R group caused some corrections in renal injury, although it could not completely restore I/R-induced renal oxidative stress and kidney damage. On the contrary, NESP administration restored kidney oxidative injury via decreasing renal lipid peroxidation and enhancing glutathione, superoxide dismutase and catalase in kidneys of the I/R group. The deviated serum levels of urea, creatinine, total proteins and uric acid were also normalized by NESP administration. Furthermore, NESP protected against renal abnormal histology features induced by I/R. Therefore, NESP has beneficial effects in preventing kidney damage and renal oxidative stress in a rat model of I/R, which deserves further evaluations in the future
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