12 research outputs found
Castles and the Frontier: Theorizing the Borders of the Principality of Antioch in the Twelfth Century
Synthesis, Reduction Chemistry, and Spectroscopic and Computational Studies of Isomeric Quinolinecarboxaldehyde Triosmium Clusters
Reactions of Electron-Deficient Triosmium Clusters with Diazomethane: Electrochemical Properties and Computational Studies of Charge Distribution
Kinase mTOR: Regulation and role in maintenance of cellular homeostasis, tumor development, and aging
Abstracts of papers presented at the 8th conference of the Entomological Society of Israel Abstracts of papers presented at the 17th congress of the Israeli Phytopathological Society
Delamination Detection in Wood – Based Composites Panel Products Using Ultrasonic Techniques
Chlorine-free biomass processing : enzymatic alternatives for bleaching and hydrolysis of lignocellulosic materials
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats
p53 in survival, death and metabolic health: a lifeguard with a licence to kill
The function of p53 as a tumour suppressor has been attributed to its ability to promote cell death or permanently inhibit cell proliferation. However, in recent years, it has become clear that p53 can also contribute to cell survival. p53 regulates various metabolic pathways, helping to balance glycolysis and oxidative phosphorylation, limiting the production of reactive oxygen species, and contributing to the ability of cells to adapt to and survive mild metabolic stresses. Although these activities may be integrated into the tumour suppressive functions of p53, deregulation of some elements of the p53-induced response might also provide tumours with a survival advantage