12 research outputs found

    Kinase mTOR: Regulation and role in maintenance of cellular homeostasis, tumor development, and aging

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    Abstracts of papers presented at the 8th conference of the Entomological Society of Israel Abstracts of papers presented at the 17th congress of the Israeli Phytopathological Society

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    Chlorine-free biomass processing : enzymatic alternatives for bleaching and hydrolysis of lignocellulosic materials

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    p53 in survival, death and metabolic health: a lifeguard with a licence to kill

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    The function of p53 as a tumour suppressor has been attributed to its ability to promote cell death or permanently inhibit cell proliferation. However, in recent years, it has become clear that p53 can also contribute to cell survival. p53 regulates various metabolic pathways, helping to balance glycolysis and oxidative phosphorylation, limiting the production of reactive oxygen species, and contributing to the ability of cells to adapt to and survive mild metabolic stresses. Although these activities may be integrated into the tumour suppressive functions of p53, deregulation of some elements of the p53-induced response might also provide tumours with a survival advantage
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