Ring-Pins combined with cable cerclage for the fixation of displaced inferior patellar pole fractures

ObjectiveThe study aimed to present the clinical results and complication rates of ring-pins with cable cerclage for treating the inferior pole of patella fracture.MethodA study that retrospectively reviewed consecutive patients of the displaced inferior pole of patella fracture (AO/OTA 34-A1) operated with a ring-pin tension band using cable cerclage between October 2015 and October 2017 was performed. The duration of surgery, motion range of the knee, function outcomes, and complications were recorded.ResultsThe average follow-up of 31 patients was 21 months. The mean operation time was 50 min. Fractures in all 31 patients healed at a mean duration of 8 weeks. There was no infection, no withdrawing of ring-pins, no implant breakage, and no loss of fracture reduction. The mean range of motion was 120°, and no patient complained of implant irritation at the final follow-up. The average Bostman score was 29.0 points, and 28 patients graded clinical outcomes excellent and 3 patients graded clinical outcomes good at the last follow-up.ConclusionsRing-pin combined with cable cerclage for treating the displaced inferior pole of patellar fracture is simple, and the postoperative internal fixation-related complication rate is low. It is a good choice for treating the displaced inferior pole of the patellar fracture

CACNA2D3 Enhances the Chemosensitivity of Esophageal Squamous Cell Carcinoma to Cisplatin via Inducing Ca2+-Mediated Apoptosis and Suppressing PI3K/Akt Pathways

Resistance to platinum-based combination chemotherapy is the main cause of poor prognosis in patients with advanced esophageal squamous cell carcinoma (ESCC). Previously, we showed that CACNA2D3 (voltage-dependent subunit alpha 2 delta 3 of a calcium channel complex) was significantly downregulated and functioned as a tumor suppressor in ESCC, but its role in the chemosensitivity of ESCC to cisplatin remained unknown. Here, we found that the expression of CACNA2D3 was significantly associated with poor platinum response in ESCC patients from the Gene Expression Omnibus database. Overexpression of CACNA2D3 increased sensitivity to cisplatin in ESCC in vitro, whereas knockdown of CACNA2D3 increased cisplatin resistance. CACNA2D3 promoted cisplatin-induced apoptosis by modulating intracellular Ca2+ stores. In vivo experiments further showed that overexpression of CACNA2D3 enhanced cisplatin anti-tumor effects in a xenograft mouse model. CACNA2D3 overexpression also resulted in the attenuation of PI3K and Akt phosphorylation. Treatment with the PI3K/Akt inhibitor LY294002 restored the chemosensitivity of CACAN2D3-knockdown cells to cisplatin. In conclusion, the results of the current study indicate that CACAN2D3 enhances the chemosensitivity of ESCC to cisplatin via inducing Ca2+-mediated apoptosis and suppressing PI3K/Akt pathways. Therefore, regulating the expression of CACNA2D3 is a potential new strategy to increase the efficacy of cisplatin in ESCC patients

Field Emission and Emission-Stimulated Desorption of ZnO Nanomaterials

Compared with other field-emission nanomaterials, 1D ZnO nanomaterials have some unique properties—such as high melting point, high thermal and chemical stability, and ambient insensitivity—which means they have promising potential applications as field emitters in harsh environments. This work proposed a water-assisted physical vapor deposition method to prepare various ZnO nanostructures simultaneously on a silicon substrate with one experimental run. Field emission characteristics of the as-grown ZnO nanomaterials were measured and analyzed. Emission-stimulated desorption was proposed and investigated. The gas released under the emission-stimulated desorption effect was measured in the way of monitoring the variation of the pressure. The results show that the slight variation of the pressure has almost no effects on the field-emissions, and field emission properties can be improved with the gases released from the surface of ZnO under the emission-stimulated-desorption effect. Finally, a low turn-on voltage in the range of 0.5–0.9 V/μm was achieved and a stable emission current was obtained. The ambient insensitivity of ZnO nanomaterials make them possible to be used as field emission cathodes in harsh environments with fluctuating pressure

Robust Ear Recognition via Nonnegative Sparse Representation of Gabor Orientation Information

Orientation information is critical to the accuracy of ear recognition systems. In this paper, a new feature extraction approach is investigated for ear recognition by using orientation information of Gabor wavelets. The proposed Gabor orientation feature can not only avoid too much redundancy in conventional Gabor feature but also tend to extract more precise orientation information of the ear shape contours. Then, Gabor orientation feature based nonnegative sparse representation classification (Gabor orientation + NSRC) is proposed for ear recognition. Compared with SRC in which the sparse coding coefficients can be negative, the nonnegativity of NSRC conforms to the intuitive notion of combining parts to form a whole and therefore is more consistent with the biological modeling of visual data. Additionally, the use of Gabor orientation features increases the discriminative power of NSRC. Extensive experimental results show that the proposed Gabor orientation feature based nonnegative sparse representation classification paradigm achieves much better recognition performance and is found to be more robust to challenging problems such as pose changes, illumination variations, and ear partial occlusion in real-world applications

Enhanced Field Emission of Single-Wall Carbon Nanotube Cathode Prepared by Screen Printing with a Silver Paste Buffer Layer

A high emission current with relatively low operating voltage is critical for field emission cathodes in vacuum electronic devices (VEDs). This paper studied the field emission performance of single-wall carbon nanotube (SWCNT) cold cathodes prepared by screen printing with a silver paste buffer layer. The buffer layer can both enforce the adhesion between the SWCNTs and substrate, and decrease their contact resistance, so as to increase emission current. Compared with paste mixing CNTs and screen printed cathodes, the buffer layer can avoid excessive wrapping of CNTs in the silver slurry and increase effective emission area to reduce the operating voltage. The experimental results show that the turn-on field of the screen-printed SWCNT cathodes is 0.9 V/μm, which is lower than that of electrophoretic SWCNT cathodes at 2.0 V/μm. Meanwhile, the maximum emission current of the screen-printed SWCNT cathodes reaches 5.55 mA at DC mode and reaches 10.4 mA at pulse mode, which is an order magnitude higher than that of electrophoretic SWCNTs emitters. This study also shows the application insight of small or medium-power VEDs

Co-sensitization to silkworm moth (Bombyx mori) and 9 inhalant allergens among allergic patients in Guangzhou, Southern China.

OBJECTIVES: This study aimed to investigate the profile of sensitization to silkworm moth (Bombyx mori) and other 9 common inhalant allergens among patients with allergic diseases in southern China. METHODS: A total of 175 patients were tested for serum sIgE against silkworm moth in addition to combinations of other allergens: Dermatophagoides pteronyssinus, Dermatophagoides farinae, Blomia tropicalis, Blattella germanica, Periplaneta americana, cat dander, dog dander, Aspergillus fumigatus and Artemisia vulgaris by using the ImmunoCAP system. Correlation between sensitization to silkworm moth and to the other allergens was analyzed. RESULTS: Of the 175 serum samples tested, 86 (49.14%) were positive for silkworm moth sIgE. With high concordance rates, these silkworm moth sensitized patients were concomitantly sensitized to Dermatophagoides pteronyssinus (94.34%), Dermatophagoides farinae (86.57%), Blomia tropicalis (93.33%), Blattella germanica (96.08%), and Periplaneta americana (79.41%). Moreover, there was a correlation in serum sIgE level between silkworm moth and Dermatophagoides pteronyssinus (r = 0.518), Dermatophagoides farinae (r = 0.702), Blomia tropicalis (r = 0.701), Blattella germanica (r = 0.878), and Periplaneta americana (r = 0.531) among patients co-sensitized to silkworm moth and each of these five allergens. CONCLUSION: In southern Chinese patients with allergic diseases, we showed a high prevalence of sensitization to silkworm moth, and a co-sensitization between silkworm moth and other five common inhalant allergens. Further serum inhibition studies are warranted to verify whether cross-reactivity exists among these allergens

Ultra low field electron emission of graphene exfoliated from carbon cloth

Graphene emitters with high enhancement factor and ultra low emission field were exfoliated from carbon fibers in carbon cloth. This method made the graphene sheets to stay on the carbon fiber and were used, in situ, as emitters. Due to their high multistage enhancement factor and intrinsic good contact, electron emission from these graphene sheets required ultra low emission field. The threshold-field corresponding to emission current density of 1 mA/cm(2) was about 0.7V/mu m. This high enhancement factor was attributed to the effects of the high aspect ratio of graphene sheets and the geometry of carbon cloth. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4758291