27 research outputs found
Efeito de doses e tipos de compostos orgânicos na produção de alface em dois solos sob ambiente protegido
Densidades populacionais para cultivares alternativas de feijoeiro no norte de minas gerais
Recuperação de matéria seca e composição química de silagens de gramíneas do gênero Cynodon submetidas a períodos de pré-emurchecimento
Acúmulo de nitrogênio, fósforo e potássio pelo algodoeiro sob irrigação cultivado em sistemas convencional e adensado
Concentração de nitrogênio na solução nutritiva e número de frutos sobre a qualidade de frutos de melão
Metabolic Profiling Of Human Blood Serum From Treated Patients With Bipolar Disorder Employing 1h Nmr Spectroscopy And Chemometrics
Metabolic profiling employing hydrogen nuclear magnetic resonance ( 1H NMR) spectroscopy and chemometric analysis of human blood serum samples taken from the control group ( n = 25) and patients with bipolar disorder ( n = 25) was performed to identify molecular changes related to the disorder and to different drug treatments: lithium ( n = 15) versus other medications ( n = 10). This strategy showed significant potential for exploring pathophysiological and toxicological features involved in bipolar disorder. The investigated groups (control and patients with bipolar disorder under different treatments) could be distinguished according to their metabolic profiles, and the main differential metabolites found were lipids, lipid-metabolism-related molecules (acetate, choline, and myo-inositol), and some key amino acids (glutamate, glutamine). 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