Entropy of the Kerr-Sen Black Hole

We study the entropy of Kerr-Sen black hole of heterotic string theory beyond semiclassical approximations. Applying the properties of exact differentials for three variables to the first law thermodynamics we derive the corrections to the entropy of the black hole. The leading (logarithmic) and non leading corrections to the area law are obtained.Comment: 8 pages. Corrected references

WISP2 (wnt-1-inducible signaling parthway protein-2)

Review on WISP2 (wnt-1-inducible signaling parthway protein-2), with data on DNA, on the protein encoded, and where the gene is implicated

Noncommutative Geometry Inspired Rotating Black Hole in Three Dimensions

We find a new rotating black hole in three-dimensional anti-de Sitter space using an anisotropic perfect fluid inspired by the noncommutative black hole. We deduce the thermodynamical quantities of this black hole and compare them with those of a rotating BTZ solution.Comment: 7 page

Synthesis, Analgesic, Anti-inflammatory and Antimicrobial Activities of Some Novel Pyrazoline Derivatives

Purpose: Microbial infections often produce pain and inflammation. Chemotherapeutic, analgesic and anti-inflammatory drugs are prescribed simultaneously in normal practice. The compound possessing all three activities is not common.The purpose of the present study was to examine whether molecular modification might result in detection of new potential antirheumatic drugs having antimicrobial activities. Method: A series of novel 4-(5′-substituted aryl-4′, 5′-dihydropyrazole-3′-yl-amino) phenols 2a-f have been synthesized by treating substituted aryl-N-chalconyl amino phenols 1a-f with hydrazine hydrate. The starting materials were synthesized from p-aminoacetophenone. Their structures were confirmed by IR, 1H NMR spectral data. The synthesized compounds were investigated for analgesic, ant-inflammatory and antimicrobial activities. Result: The data reported in Tables 2, 3 & 4 shows that effect of variation in chemical structure on activity was rather unpredictable. Seldom did a particular structural modification lead to uniform alteration in activity in all tests. The substitution which appeared to be most important for high order of activity in the greatest number of test was the p-choloroaryl group. The introduction of p-nitro and p-hydroxy group in aryl moiety of the pyrazole analogs 2c and 2e produce compounds with potent analgesic, anti-inflamatory and, in a few cases, antimicrobial properties. Conclusion: The observed increase in analgesic, anti-inflammatory and antimicrobial activities are attributed to the presence of 4-NO2, 2-OH and 4-Cl in phenyl ring at 5-position of pyrazoline ring of synthesized compounds. In some cases their activities are equal or more potent than the standard drugs. Keywords: Pyrazole, Analgesic, Anti-inflammatory, Antibacterial activity Tropical Journal of Pharmaceutical Research Vol. 7 (2) 2008: pp. 961-96

Synthesis and Biological Evaluation of some Anthranilic Acid and 2-Phenylquinazoline-4(3H)-one Analogues

In the present investigation a novel series of N-(phenyl) chalconyl anthranilic acids containing pyrazolines (4a–j), tetrahydropyrimidines (4k–o), tetrahydrothiopyrimidines (4p–t) and 2-phenylquinazolin-4(3H)-ones containing pyrazolines (8a–f), isoxazolines (8g–l), tetrahydropyrimidines (8m–r) and tetrahydrothiopyrimidines (8s–x) were synthesized and characterized by elemental analysis, FT-IR, 1H NMR and mass spectroscopy. The title compounds (4a–t) and (8a–x) were investigated for their analgesic, anti-inflammatory, antimicrobial and in vitro protein denaturation activities. Compounds 4j and 8x were identified as lead compounds with optimum analgesic, anti-inflammatory and antimicrobial activities.Keywords: Quinazolines, antimicrobial, analgesic, anti-inflammatory, protein denaturatio