Second trimester inflammatory and metabolic markers in women delivering preterm with and without preeclampsia.

ObjectiveInflammatory and metabolic pathways are implicated in preterm birth and preeclampsia. However, studies rarely compare second trimester inflammatory and metabolic markers between women who deliver preterm with and without preeclampsia.Study designA sample of 129 women (43 with preeclampsia) with preterm delivery was obtained from an existing population-based birth cohort. Banked second trimester serum samples were assayed for 267 inflammatory and metabolic markers. Backwards-stepwise logistic regression models were used to calculate odds ratios.ResultsHigher 5-α-pregnan-3β,20α-diol disulfate, and lower 1-linoleoylglycerophosphoethanolamine and octadecanedioate, predicted increased odds of preeclampsia.ConclusionsAmong women with preterm births, those who developed preeclampsia differed with respect metabolic markers. These findings point to potential etiologic underpinnings for preeclampsia as a precursor to preterm birth

A new phase of bis[2-(diphenylphosphino-\u3baP)phenylazanido-\u3baN](ethanolato)(oxo)rhenium(V)

The title compound, [Re(C18H15NP)2(C2H5O)O], was synthesized by the oxidation-substitution reaction of [Re(III)(PNH)2(PNH2)]Cl, where PNH2 is 2-(diphenylphosphino)phenylamine, with NEt3 in EtOH. The X-ray diffraction study of this new triclinic phase, designated beta, confirms the molecular structural details for the monoclinic a isomer, which crystallized in space group P2(1)/c with a = 12.056 (3), b = 26.303 (6), c = 11.005 (3) angstrom, beta = 102.32 (2)-degrees [Refosco, Tisato, Bandoli, Bolzati, Dolmella, Moresco & Nicolini (1993). J. Chem. Soc. Dalton Trans. pp. 605-618]

Synthesis and NMR investigation on mer-[Re(III)Cl(3)(L)(3)] and mer-[Re(III)Cl(3)(L)(2)(PPh(3))] complexes (L = pyridine-like ligand). X-ray structure of mer-[Re(III)Cl(3)(3,5-lut)(3)]

The co-ordination geometry of the monomeric rhenium complexes mer-[Re(III)Cl(3)(L)(3)] (L = py 1,3,5-lut 2, 4-pic 3) has been determined in the solid state by single X-ray diffraction of the representative complex 2 and in solution by proton NMR spectroscopy. Only a single stable conformation has been found in the solid state and in solution, under the experimental conditions utilised. The NMR spectra of the related complexes mer-[Re(III)Cl(3)(L)(2)(PPh(3))] (L = py 4, 3,5-lut 5, 4-vinpy 6) have also been reported for comparison purposes. (C) 1998 Elsevier Science Ltd. All rights reserved

Mononuclear six-coordinated Ga(III) complexes: A comprehensive survey

Given the commercial availability of (68)Ge-(68)Ga generators, in principle analogous to the worldwide utilized (99)Mo-(99m)Tc generator, it is surprising that few (68)Ga agents have been developed beyond basic research toward clinical application. The use of the unconventional (68)Ga positron emitter would allow for a cost-effective production of (68)Ga radiotracers far from a cyclotron facility. Moreover, the use of (67)Ga radiopharmaceuticals for imaging studies, and the application of non-radioactive gallium compounds in the treatment of important disorders, including a number of cancer and infectious diseases, make studies on trivalent Ga coordination chemistry attractive for the design of novel gallium-based drugs. The aim of this review is to survey the reported crystal data of six-coordinated Ga(III) complexes in order to gain information to be used in the design of novel Ga complexes of medicinal interes

Structural overview of technetium compounds (1993-1999)

This paper investigates the structural aspects of technetium-containing complexes. The focus is on the description of the various coordination environments around the technetium center. The complexes are divided according to the coordination sphere and the most significant structural parameters are reviewed and discussed. The review covers the crystallographic determinations published in the years between 1993 and 1999. (C) 2001 Elsevier Science B.V. All rights reserved

Structural overview of technetium compounds (2000-2004)

This paper provides an overview of the about 80 crystal structures of technetium complexes described in the past 5 years and exhibiting some peculiar structural features. In almost 90% of the compounds, technetium shows an odd oxidation number, and by a large majority the revised complexes are mononuclear and neutral. The review especially focuses on nitrido-Tc(V), oxo-Tc(V) and fac-[Tc(CO)(3)](+) complexes, which cover approximately one-half of the X-ray structural reports

Synthesis, characterization and electrochemical studies on technetium(V) and rhenium(V) oxo-complexes with N,N\u2032-2-hydroxypropane-1,3-bis(salicylideneimine)

Ligand-exchange reactions of potential quinquedentate Schiff base ligands derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane (H3L) with [MOCl4] 12 (M = Tc and Re) have been investigated. The complexes [MOCl2(R-OH)(H2L\ub7HCl)] (I) (R = Me, Et), [ReOCl(HL)] (II) and \u3bc-O[MO(HL)]2 (III) were synthesized and characterized by the usual physicochemical measurements. Cyclic voltammetries for both III complexes reveal two separate and single-electron redox processes. The crystal structure of \u3bc-O[TcO(HL)]2 was determined by single-crystal X-ray diffraction methods. Crystals are monoclinic, space group P21/c, with a = 9.423(6), b = 19.666(9), c = 22.785(11) \uc5, \u3b2 = 99.41(4)\ub0 and Z = 4. X-ray diffraction provides 2842 observed reflections (up to \u3b8 = 40\ub0) and the structure has been refined by full-matrix least-squares methods to R = 0.10. The \u2018dimeric\u2019 structure of \u3bc-O[TcO(HL)]2 consists of two distorted octahedral TcO(HL) moieties bridged by an oxygen atom which occupies the sixth coordination site of each moiety with the Tc-O-Tc angle nearly linear (173\ub0)