To study prevalence of incipient iron deficiency in primary hypothyroidism

Background: Hypothyroidism, affects around 1% of general population. Anemia in association with hypothyroidism has been studied since 1881. Iron deficiency has multiple adverse effects on thyroid metabolism. It decreases circulating thyroid hormone concentration, blunts thyrotrophic response to TRH, decreases serum T3. Objective of current study was to find prevalence of iron deficiency in primary hypothyroid.Methods:In our study 70 patients were selected, out of which 50 were females and 20 were males, who were suffering from hypothyroidism. Iron deficiency in the study group was confirmed at baseline using multiple iron status indicators (serum ferritin, serum iron, TIBC & percentage Saturation). These patients were between age group 18-65 years.Results: In our study only 14 patients (20%) manifested with anemia (which was defined as Hb<12gm/dl), where as the prevalence of iron deficiency (with or without anemia) was 34.2%, in which 28.5% were females and 5.70% were males, thus showing that prevalence of iron deficiency (with or without anemia) can be higher than iron deficiency anemia itself, which is supported by literature.Conclusion:Iron deficiency was present in a significant portion of patients with primary hypothyroidism. It also concluded that frequency of iron deficiency (with or without anemia) was higher than iron deficiency anemia.

A rare presentation of miller fisher syndrome- a case report

In this report we describe a rare presentation of Miller Fisher syndrome, a variant of Guillain Barre Syndrome. This distinctive syndrome is an acute immune mediated neuropathies usually preceded by an infectious illness characterized by total external ophthalmoplegia, severe ataxia and tendon areflexia. The presence of the IgG anti-GQ1b antibody in serum is an excellent diagnostic marker for MFS. This antibody often cross reacts with GT1a and is patho physiologically associated with ophthalmoplegia or ataxia in MFS and GBS

Recurrent vertigo and intermittent jaw pain as primary presentation in Takayasu's arteritis

Takayasu’s arteritis (TA) is a non‐specific arteritis with an unknown cause, affecting predominantly the aorta and its major branches. It is common in females in the second and third decades of life. We report a case of 32year female who presented with recurrent vertigo and intermittent jaw pain

Double osteomalacia

35-year old woman presented, with chronic vague ill health, subacute symptoms of decreased appetite, increased thirst, excessive urination, and rib pains, and acute quadriparesis. On evaluation, she was found to have type 1 Renal tubular acidosis, pseudofractures of ribs and Hypovitaminosis D. Administration of oral solution containing potassium citrate and citric acid along with pharmacological doses of Vitamin D and supportive treatment improved her condition remarkably. This case report highlights interesting coexistence of two disorders, one very common (Hypovitaminosis D) and one rare (Distal Renal Tubular Acidosis dRTA), in same patient, producing same pathology (osteomalacia

Thyrotoxicosis with primary presentation as dysphagia: a rare manifestation

Thyrotoxicosis refers to the clinical manifestations associated with elevated serum levels of T4 or T3 in an individual. Dysphagia is a common problem but a rare manifestation of hyperthyroidism. Dysphagia is an uncommon manifestation of thyrotoxic myopathy. Reports have been sparse and its incidence is not clear. In our case report patient presented who with dysphagia and weight loss and investigation revealed hyperthyroidism. Patient dysphagia subsequently resolved after receiving treatment with methimazole and beta-blockers. This case report the need to include thyrotoxicosis in the differential diagnosis of an otherwise unexplained case of dysphagia

Scholars Journal of Medical Case Reports ISSN 2347-9507 (Print) Transmural Migration of Mesh after Abdominal Rectopexy Presenting as Large Bowel Obstruction: A Rare Cause

Abstract: This case reports the presentation and investigation of a 55-year-old woman presenting with symptoms of large bowel obstruction and found to have synchronous intraluminal migration of a polypropylene mesh from a abdominal rectopexy done 2.5 yrs back. Mesh migration is an infrequent occurrence, and is rarely reported in the literature. Those that are usually involve the urinary bladder. In particular, review of literature shows no reports of cases of mesh migration into the rectum several years after into the rectum presenting as sub acute intestinal obstruction

“Excess gooD can be Dangerous”. A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D

Vitamin D is increasingly recognized to have several beneficial effects. Its toxicity, causing hypercalcemia, is considered as extremely rare. We report case series of 15 patients (most of them being elderly subjects) with iatrogenic symptomatic hypercalcemia in whom toxicity occurred due to empirical excessive administration of vitamin D by oral and parenteral rout