5 research outputs found
Les prénoms des habitants de Mirande au XVIIe et au XVIIIe siècles
Houth-Baltus Madeleine. Les prénoms des habitants de Mirande au XVIIe et au XVIIIe siècles. In: Revue Internationale d'Onomastique, 8e année N°1, mars 1956. pp. 31-42
Marche - Marchais, lettre de Madame Madeleine Houth, 18 octobre 1968
Houth-Baltus Madeleine. Marche - Marchais, lettre de Madame Madeleine Houth, 18 octobre 1968. In: Revue Internationale d'Onomastique, 21e année N°1, mars 1969. pp. 76-77
La structure agraire et son expression dans les lieux-dits d’une région de l’Ile-de-France (pays de Cruye, val de Galie)
Houth-Baltus Madeleine. La structure agraire et son expression dans les lieux-dits d’une région de l’Ile-de-France (pays de Cruye, val de Galie). In: Onomastica. Revue Internationale de Toponymie et d'Anthroponymie, 1e année N°3-4, Septembre-décembre 1947. Deuxième congrès international de toponymie et d'anthroponymie, Paris 15-19 juillet 1947. pp. 297-301
GATA Transcription Factors Regulate the Expression of the Human Eosinophil-derived Neurotoxin (RNase 2) Gene*
The transcription factors GATA-1 and GATA-2 have been implicated in
promoting differentiation of eosinophilic leukocytes. In this study, we
examined the roles of GATA-1 and GATA-2 in activating transcription of the
secretory ribonuclease, the eosinophil-derived neurotoxin (EDN/RNase 2).
Augmented expression of both GATA-1 and GATA-2 was detected
in eosinophil promyelocyte HL-60 clone 15 cells in response to biochemical
differentiation with butyric acid. Deletion or mutation of one or both of the
two consensus GATA-binding sites in the extended 1000-bp 5′ promoter of
the EDN gene resulted in profound reduction in reporter gene
activity. Antibody-augmented electrophoretic mobility shift and chromatin
immunoprecipitation analyses indicate that GATA-1 and GATA-2 proteins bind to
both functional GATA consensus sequences in the EDN promoter.
Interestingly, RNA silencing of GATA-1 alone had no impact on EDN
expression; silencing of GATA-2 resulted in diminished expression of
EDN, and also diminished expression of GATA-1 in both
butyric acid-induced HL-60 clone 15 cells and in differentiating human
eosinophils derived from CD34+ hematopoietic progenitors. Likewise,
overexpression of GATA-2 in uninduced HL-60 clone 15 cells resulted in
augmented transcription of both EDN and GATA-1. Taken
together, our data suggest that GATA-2 functions directly via interactions
with the EDN promoter and also indirectly, via its ability to
regulate the expression of GATA-1 in differentiating eosinophils and
eosinophil cell lines