Affective interactions between expressive characters

When people meet in virtual worlds they are represented by computer animated characters that lack a variety of expression and can seem stiff and robotic. By comparison human bodies are highly expressive; a casual observation of a group of people mil reveals a large diversity of behavior, different postures, gestures and complex patterns of eye gaze. In order to make computer mediated communication between people more like real face-to-face communication, it is necessary to add an affective dimension. This paper presents Demeanour, an affective semi-autonomous system for the generation of realistic body language in avatars. Users control their avatars that in turn interact autonomously with other avatars to produce expressive behaviour. This allows people to have affectively rich interactions via their avatars

Direct Manipulation-like Tools for Designing Intelligent Virtual Agents

If intelligent virtual agents are to become widely adopted it is vital that they can be designed using the user friendly graphical tools that are used in other areas of graphics. However, extending this sort of tool to autonomous, interactive behaviour, an area with more in common with artificial intelligence, is not trivial. This paper discusses the issues involved in creating user-friendly design tools for IVAs and proposes an extension of the direct manipulation methodology to IVAs. It also presents an initial implementation of this methodology

Rotorcraft flight-propulsion control integration

The NASA Ames and Lewis Research Centers, in conjunction with the Army Research and Technology Laboratories have initiated and completed, in part, a joint research program focused on improving the performance, maneuverability, and operating characteristics of rotorcraft by integrating the flight and propulsion controls. The background of the program, its supporting programs, its goals and objectives, and an approach to accomplish them are discussed. Results of the modern control governor design of the T700 and the Rotorcraft Integrated Flight-Propulsion Control Study, which were key elements of the program, are also presented

Rotorcraft flight-propulsion control integration: An eclectic design concept

The NASA Ames and Lewis Research Centers, in conjunction with the Army Research and Technology Laboratories, have initiated and partially completed a joint research program focused on improving the performance, maneuverability, and operating characteristics of rotorcraft by integrating the flight and propulsion controls. The background of the program, its supporting programs, its goals and objectives, and an approach to accomplish them are discussed. Results of the modern control governor design of the General Electric T700 engine and the Rotorcraft Integrated Flight-Propulsion Control Study, which were key elements of the program, are also presented

Immune activation, immune senescence and levels of Epstein Barr Virus in kidney transplant patients: Impact of mTOR inhibitors

Post-transplant lymphoproliferative disorders (PTLD) represent a severe complication in transplanted patients and Epstein-Barr Virus (EBV) is the main driver. Besides immunodepression, immune activation/chronic inflammation play an important role in both virus reactivation and expansion of EBV-positive B cells. The aim of this study was to assess the impact of immunosuppressive strategies on factors involved in the PTLD's pathogenesis. 124 kidney transplanted patients were enrolled in this study: 71 were treated with mycophenolic acid (MPA) and 53 treated with mTOR inhibitor (mTORi), both in combination with different doses of calcineurin inhibitor. At the time of the transplant (T0), profile of inflammation/immune activation and immune senescence didn't differ between the two groups, but after one year of treatment (T1) markers were significantly higher in MPA-treated patients; their immunosenescence process was supported by the greater erosion of telomeres despite their younger age. Percentages of activated B cells and levels of EBV-DNA significantly increased in MPA-treated patients, and at T1 were significantly higher in MPA- than in mTORi-treated patients. Overall, these findings indicate that mTOR inhibitors constrain the inflammation/immune activation and senescence status, thus reducing the expansion of EBV-infected B cells and the risk of virus-associated PTLD in kidney transplant recipients. \ua9 2019 The Author