Cochlear implantation in elderly: indication and results

The aim of the study was to investigate the outcome of CI among elderly cochlear implant recipients. Results from our study have shown that elder patient implanted above 75 yrs can obtain significant hearing benefit from cochlear implantation. Similarly to the results reported by Vermeer1, in our study subjects implanted at elder age show lower scores compared to younger adult implantees

XMM-Newton discovery of a sharp spectral feature at ~7 keV in the Narrow-Line Seyfert 1 galaxy 1H 0707-495

We report the first detection of a sharp spectral feature in a Narrow-Line Seyfert 1 galaxy. Using XMM-Newton we have observed 1H0707-495 and find a drop in flux by a factor of more than 2 at a rest-frame energy of ~7 keV without any detectable narrow Fe K alpha line emission. The energy of this feature suggests a connection with the neutral iron K photoelectric edge, but the lack of any obvious absorption in the spectrum at lower energies makes the interpretation challenging. We explore two alternative explanations for this unusual spectral feature: (i) partial covering absorption by clouds of neutral material and (ii) ionised disc reflection with lines and edges from different ionisation stages of iron blurred together by relativistic effects. We note that both models require an iron overabundance to explain the depth of the feature. The X-ray light curve shows strong and rapid variability, changing by a factor of four during the observation. The source displays modest spectral variability which is uncorrelated with flux.Comment: 5 pages incl. 6 figures, accepted for publication in MNRA

X-ray Reflection from Inhomogeneous Accretion Disks: II. Emission Line Variability and Implications for Reverberation Mapping

One of the principal scientific objectives of the upcoming Constellation-X mission is to attempt to map the inner regions of accretion disks around black holes in Seyfert galaxies by reverberation mapping of the Fe K fluorescence line. This area of the disk is likely radiation pressure dominated and subject to various dynamical instabilities. Here, we show that density inhomogeneities in the disk atmosphere resulting from the photon bubble instability (PBI) can cause rapid changes in the X-ray reflection features, even when the illuminating flux is constant. Using a simulation of the development of the PBI, we find that, for the disk parameters chosen, the Fe K and O VIII Ly\alpha lines vary on timescales as short as a few hundredths of an orbital time. In response to the changes in accretion disk structure, the Fe K equivalent width (EW) shows variations as large as ~100 eV. The magnitude and direction (positive or negative) of the changes depends on the ionization state of the atmosphere. The largest changes are found when the disk is moderately ionized. The O VIII EW varies by tens of eV, as well as exhibiting plenty of rapid, low-amplitude changes. This effect provides a natural explanation for some observed instances of short timescale Fe K variability which was uncorrelated with the continuum (e.g., Mrk 841). New predictions for Fe K reverberation mapping should be made which include the effects of this accretion disk driven line variability and a variable ionization state. Reflection spectra averaged over the evolution of the instability are well fit by constant density models in the 2-10 keV region.Comment: 20 pages, 3 figures. Accepted by Ap

Computer Components and Systems

Contains reports on three research projects.United States Navy, Bureau of Ships (Contract NObsr 77603

A softer look at MCG--6-30-15 with XMM-Newton

We present analysis and results from the Reflection Grating Spectrometer during the 320 ks XMM observation of the Seyfert 1 galaxy MCG-6-30-15. The spectrum is marked by a sharp drop in flux at 0.7 keV which has been interpreted by Branduardi-Raymont et al. as the blue wing of a relativistic OVIII emission line and by Lee at al. as a dusty warm absorber. We find that the drop is well explained by the FeI L2,3 absorption edges and obtain reasonable fits over the 0.32-1.7 keV band using a multizone, dusty warm absorber model. Some residuals remain which could be due to emission from a relativistic disc, but at a much weaker level than from any model relying on relativistic emission lines alone. A model based on such emission lines can be made to fit if sufficient (warm) absorption is added, although the line strengths exceed those expected. The EPIC pn difference spectrum between the highest and lowest flux states of the source indicates that this is a power-law in the 3-10 keV band which, if extrapolated to lower energies, reveals the absorption function acting on the intrinsic spectrum, provided that any emission lines do not scale exactly with the continuum. We find that this function matches our dusty warm absorber model well. The soft X-ray spectrum is therefore dominated by absorption structures, with the equivalent width of any individual emission lines in the residuals being below about 30 eV. (abridged)Comment: 8 pages, 10 figures, submitted to MNRA

Resolving the cosmic X-ray background with a next-generation high-energy X-ray observatory

The cosmic X-ray background (CXB), which peaks at an energy of ~30 keV, is produced primarily by emission from accreting supermassive black holes (SMBHs). The CXB therefore serves as a constraint on the integrated SMBH growth in the Universe and the accretion physics and obscuration in active galactic nuclei (AGNs). This paper gives an overview of recent progress in understanding the high-energy (>~10 keV) X-ray emission from AGNs and the synthesis of the CXB, with an emphasis on results from NASA's NuSTAR hard X-ray mission. We then discuss remaining challenges and open questions regarding the nature of AGN obscuration and AGN physics. Finally, we highlight the exciting opportunities for a next-generation, high-resolution hard X-ray mission to achieve the long-standing goal of resolving and characterizing the vast majority of the accreting SMBHs that produce the CXB.Comment: Science White paper submitted to Astro2020 Decadal Survey; 5 pages, 3 figures, plus references and cover pag

Sex-related differences in premature cardiovascular disease in familial hypercholesterolemia

BACKGROUND: Familial hypercholesterolemia (FH) is associated with an increased prevalence of premature atherosclerotic cardiovascular disease (ASCVD), however, little is known about sex-specific differences in premature ASCVD and its risk factors. OBJECTIVE: The present study seeks to assess the burden and risk factors for premature ASCVD among men and women with FH. METHODS: In this study we retrospectively examined sex-specific differences in ASCVD prevalence, risk factor burdens, and lipid treatment outcomes in 782 individuals with clinically or genetically confirmed FH treated in 5 U.S. lipid and genetics clinics. A generalized linear model using Binomial distribution with random study site effect and sex-stratified analysis was used to determine the strongest predictors of premature ASCVD, and lipid treatment outcomes. Covariates included age, sex, diabetes mellitus (DM), hypertension, and current smoking. RESULTS: Among the cohort, 98/280 men (35%) and 89/502 women (18%) had premature ASCVD (defined as \u3c55 years in men and \u3c65 years in women). Women with premature ASCVD had higher mean treated total cholesterol (216 vs. 179 mg/dl, p=\u3c0.001) and LDL-C (135 vs. 109 mg/dl, p= 0.005). CONCLUSION: These data confirm that high percentages of women and men with FH develop premature ASCVD, and suggest that FH may narrow the observed sex difference in premature ASCVD onset. These data support more aggressive prevention and treatment strategies in FH, including in women, to reduce non-lipid risk factors and residual hypercholesterolemia

Far Infrared Spectroscopy

Contains reports on five research projects