319 research outputs found
Numerical Simulations of Pinhole and Single Mode Fibre Spatial Filters for Optical Interferometers
We use a numerical simulation to investigate the effectiveness of pinhole
spatial filters at optical/IR interferometers and to compare them with
single-mode optical fibre spatial filters and interferometers without spatial
filters. We show that fringe visibility measurements in interferometers
containing spatial filters are much less affected by changing seeing conditions
than equivalent measurements without spatial filters. This reduces visibility
calibration uncertainties, and hence can reduce the need for frequent
observations of separate astronomical sources for calibration of visibility
measurements. We also show that spatial filters can increase the
signal-to-noise ratios of visibility measurements and that pinhole filters give
signal-to-noise ratios within 17% of values obtained with single-mode fibres
for aperture diameters up to 3r_0. Given the simplicity of the use of pinhole
filters we suggest that it represents a competitive, if not optimal, technique
for spatial filtering in many current and next generation interferometers.Comment: 7 pages, 7 postscript figures. Accepted by MNRA
IKK/Nuclear Factor-kappaB and Oncogenesis: Roles in tumor-initiating cells and in the tumor microenvironment
The IKK/nuclear factor-kappaB pathway (NF-κB) is critical in proper immune function, cell survival, apoptosis, cellular proliferation, synaptic plasticity, and even memory. While NF-κB is crucial for both innate and adaptive immunity, defective regulation of this master transcriptional regulator is seen in a variety of diseases including autoimmune disease, neurodegenerative disease, and, important to this review, cancer. While NF-κB functions in cancer to promote a number of critical oncogenic functions, here we discuss the importance of the NF-κB signaling pathway in contributing to cancer through promotion of the tumor microenvironment and through maintenance/expansion of tumor-initiating cells, processes that appear to be functionally interrelated
High-Efficiency Neutron Detectors
This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440
Energy Dependence of Cross Sections for Stretched States Excited in (p,n) Reactions
This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440
High-Spin States Excited Via (p,n) Reactions
This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit
Stretched State Excitations in the 26-Mg(p,n)26-Al Reaction at 134 MeV
This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440
Performance of Large-Volume, Mean-Timed Neutron Detectors
This work was supported by the National Science Foundation Grants NSF PHY 78-22774 A03, NSF PHY 81-14339, and by Indiana Universit
High-Spin "Stretched" States Excited in (p,n) Reactions
This work was supported by the National Science Foundation Grant NSF PHY 78-22774 A02 & A03 and by Indiana Universit
Performance of Large-Volume Mean-Timed Neutron Detectors
Supported by the National Science Foundation and Indiana Universit
Measurements of Gamow-Teller Strength for Double-Beta Decaying Nuclei Via the (p,n) Reaction at 134 MeV
This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit
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