A study of antenatal anxiety: comparison across trimesters

Background: The aim of present study was to investigate the antenatal anxiety across all three trimesters of pregnancy.Methods: This is a cross sectional, observational study for which data is collected from consenting subjects attending antenatal Out Patients department for routine antenatal checkup. Data included socio demographic information’s and Hospital Anxiety and Depression Scale and statistical analysis done.Results: Out of 169 Pregnant females 27.8% were during first trimester, 40.8% during second trimester and 31.4% during 3rd trimester. The mean anxiety scores for first, second and third trimester was 10.74±2.97, 11.69±3.09 and 14.20±3.10 respectively. Independent t test revealed significantly higher anxiety scores for third trimester when compared to first trimester scores (t= -6.035, p value = 0.000).Conclusions: This study finds a significantly higher antenatal anxiety during third trimester of pregnancy

Effect of hydroxychloroquine in viral clearance in nCOV-19 infected patient admitted in tertiary care centre, Ranchi, Jharkhand, India

Background: In view of recent publications of conflicting evidence on the safety and efficacy of hydroxychloroquine as prophylaxis and as a treatment for COVID-19 patients, we need to assess the effect of hydroxychloroquine in COVID-19 patients of authors own local population.Methods: In this retrospective chart review study, categorization of confirmed COVID-19 cases nasopharyngeal swab of RT-PCR was done into a group of patients who received hydroxychloroquine standard dose and another control group who did not receive hydroxychloroquine. The main comparing parameter was to see virus clearance days across both groups.Results: A total of 112 patients were included for the study, and grouped of 72 patient who received HCQS and remaining 40 patients as control. The virus clearance time in days was found to be 9.01±3.08 for HCQS group and for control group it was 8.64±2.34 days (Man Whitney U test value = 2.13, p=0.756).Conclusions: There is no significant difference found in attaining virus negative status with use of HCQS administration in this study

Multiple self-inserted pins and nails in pericardium in a patient of schizophrenia: Case report and review

This report is the case of multiple self-inserted pins and nails in chest and pericardial cavity in a young male suffering from schizophrenia. This act of self-mutilation was done to get relief from burning sensation in chest and palpitations. Review of the relevant literature revealed that self-inflicted intra-cardiac needle injuries occur mainly in young and middle-aged adults suffering from psychiatric disorders, commonly depression, schizophrenia, and substance use disorders. In one-fourth of the patients, it is due to deliberate self-harm. About 70% use a single needle but 30% may use multiple needles. Second attempts are rare. Majority of the patients (85%) are managed by surgery and recover from the injury. The condition has a low mortality rate of 5%

Cycloserine induced mania

We report a 21-year-old male who developed manic symptoms after addition of second line anti-tuberculosis treatment for his multidrug resistant tuberculosis. We identified cycloserine as offending drug; and discuss the management and possible neurobiological mechanisms as etiological explanation and implications of manic switch caused by cycloserine

Effect of Edible Coating on Shelf-life Enhancement of Papaya (Carica papaya L.) at Ambient Conditions

An experiment was conducted on the effect of edible coating on shelf-life enhancement of papaya (Carica papaya L.) at ambient conditions. The main aim of this study was to increase the shelf life of papaya by using edible coating. Postharvest losses in fruits is a serious problem due to rapid deterioration during storage. Use of edible coatings over fruits is used to improve their quality and enhance the shelf life. The main purpose of this study was to assess the effect of aloe vera gel, beeswax, paraffin wax and gelatine coating in extending the shelf-life of papaya including physico-chemical changes under ambient storage conditions. The experiment was laid out in completely randomized design (CRD) with 7 treatments and 3 replications. The treatment consisted of coating material with Aloe vera gel 0.5% (T1), Aloe vera gel 1%(T2), Aloe vera gel 1.5%(T3), Beeswax 6% (T4), Paraffin wax 100% (T5), Gelatin10%(T6), Control(T7) and freshly harvested papaya fruits. Statistical analysis revealed that among all the treatments, the maximum effect on extending the shelf-life and delaying the ripening was recorded in paraffin wax coated papaya fruits. Therefore, coating of papaya fruits with paraffin wax can be suggested as a post-harvest treatment to enhance the shelf-life

Factor Structure of CIWA-Ar in Alcohol Withdrawal

Objective. To identify the underlying factor structure of alcohol withdrawal syndrome, as measured with CIWA-Ar. Methods. Exploratory factor analysis was conducted on the items of CIWA-Ar. On 201 alcohol-dependent male patients seeking treatment for alcohol withdrawal at 36 hours of abstinence. Results. A three-factor solution was obtained that accounted for 68.74% of total variance. First factor had loading from four items (34.34% variance), second factor also had four items (24.25% variance), and the third had two items (10.04% variance). Conclusions. Factor analysis reveals the existence of multidimensionality of alcohol withdrawal as measured with CIWA-Ar and we found three factors that can be named as delirious, autonomic and nonspecific factors

Depression and Anxiety following Coronary Artery Bypass Graft: Current Indian Scenario

Epidemiological studies have shown a high prevalence of coronary artery disease among the Indian Population. Due to increasing availability and affordability of tertiary care in many parts of India, carefully selected patients undergo coronary artery bypass surgery to improve cardiac function. However, the procedure is commonly associated with depression and anxiety which can adversely affect overall prognosis. The objective of this review is to highlight early identifiable symptoms of depression and anxiety following coronary artery bypass graft (CABG) in Indian context so as to facilitate prompt intervention for better outcome. The current review was able to establish firm evidence in support of screening for depression and anxiety following CABG. Management of depression and anxiety following CABG is briefly reviewed

Anxiety in school students: Role of parenting and gender

Background: The prevalence of anxiety is high in school going children; however pattern of parenting and gender of the child are important factors for the development of anxiety. Gender role and parenting patterns are important construct that vary across different sociocultural setting hence are important to be studied in Indian context. Materials and Methods: In a cross sectional study all students of both sexes studying in class VIII, were assessed using the Spence anxiety scale (children version). Results: The sample consisted of 146 (55% male and 45% female) with a mean age of 12.71 years. A total of 16 (11%) students scored above cutoff for high anxiety, the mean scores across gender shows that female students scored significantly higher in total and all sub types of anxiety. Most of the students perceived their parents ′Democratic′ and other two authoritarian and permissive type of parenting were almost equal. There was significantly higher anxiety among the students who perceived their parents as authoritarian. Conclusions: The prevalence of high anxiety was 11% in class VIII students. High anxiety in students was significantly associated with female gender and authoritarian parenting pattern as perceived by the children