3 research outputs found

    Finishing the euchromatic sequence of the human genome

    Get PDF
    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Seguridad alimentaria y estado nutricional en comunidades pescadoras de la amazonia boliviana : resultados de una encuesta de hogares

    No full text
    There are high levels of food insecurity in the Bolivian Amazon, and fishing communities have particular kinds of under nutrition and food insecurity. A primary focus of this study is the relationship between household food insecurity and childhood stunting. Variables that have been associated with stunting in other contexts are not associated with stunting in this population. Parasitic intestinal infections contribute to stunting rates in the Amazon Basin and variables found to correlate with childhood stunting included incomplete knowledge of breastfeeding and of feeding a sick child, and inadequate toilet facilities. Maternal overweight was associated with older age and some socio-economic variables.Master's degre

    [The effect of low-dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock].

    No full text
    corecore