2 research outputs found
Metal-Catalyzed Domino Synthesis of Benzophenanthridines and 6<i>H</i>‑Naphtho[2,3‑<i>c</i>]‑chromenes
A new and efficient synthesis of
tetracyclic phenanthridines and
benzoÂ[<i>c</i>]Âchromenes has been described involving a
metal-mediated two-step domino strategy. The first step involved efficient
palladium-catalyzed domino carbopalladation/cross coupling, and the
second step involved iron-catalyzed domino isomerization/cyclodehydration.
The important features of this strategy include high yields, generality,
wide substrate scope, and broad functional group tolerance. A plausible
mechanism has been proposed to explain the formation of the product
Metal-Catalyzed Domino Synthesis of Benzophenanthridines and 6<i>H</i>‑Naphtho[2,3‑<i>c</i>]‑chromenes
A new and efficient synthesis of
tetracyclic phenanthridines and
benzoÂ[<i>c</i>]Âchromenes has been described involving a
metal-mediated two-step domino strategy. The first step involved efficient
palladium-catalyzed domino carbopalladation/cross coupling, and the
second step involved iron-catalyzed domino isomerization/cyclodehydration.
The important features of this strategy include high yields, generality,
wide substrate scope, and broad functional group tolerance. A plausible
mechanism has been proposed to explain the formation of the product