712 research outputs found

    Effect of strength of gravitational field on electrode processes

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    Gravitational transformation of free energy dictates cell potential to be lower near the vicinity of massive planet which results in the slower oxidation and reduction of ions at their respective electrodes, in lower gravitational field. The newly formulated gravitational transformations formulates decrease in the electrode potential, cell potential and electrochemical rate constants at lower gravitational field, this is due to greater flux of gravitons escaping in to higher dimensions at lower gravitational fields than at higher gravitational fields

    The Influence of r/WallstreetBets on GameStop stock price: A Behavioural Finance Perspective

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    Treballs Finals del Grau de d'Administració i Direcció d'Empreses, Facultat d'Economia i Empresa, Universitat de Barcelona, Curs: 2023-2024 , Tutor: Bàrbara Llacay PintatThe aim of this paper is twofold. First to empirically explore the GameStop stock surge that occurred in January 2021 from the behavioral finance perspective and second to analyze the impact of retail investor sentiment expressed on Reddit's WallStreetBets using Natural language processing (NLP). By following a quantitative methodology which included correlation analysis, regression models, and Granger causality tests, this research seeks to prove the effect of retail investor sentiment in the the abnormal movements of GameStop stock prices. By integrating and applying key theories of behavioral finance Herding, Fear of Missing Out (FOMO), this research shows that there are clear patterns that are highly suggestive of profound correlations between social media-driven sentiment and how this amplifies these biases. The findings empirically demonstrate that sentiment on WallstreetsBets had an influence on Gamestop stock price and how the present biases can disrupt market normalcy and develop new viewpoints in a digitally impacted financial era

    Evaluation of performance of various histological grading systems of soft tissue sarcomas and the prognosis (metastatic risk and survival rate)

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    Background: Histologic grade represents the most important prognostic factor for all soft tissue sarcomas and it is strongly associated with the advent of metastasis and patients survival. The main objective of this study is to test individual grading system with metastatic risk and patients survival rate (prognosis).Methods: Soft tissue sarcomas (250) were graded by FNCLCC, NCI & Mhyre Jensens grading system. Special stains & immunohistochemistry were employed whenever necessary.Results: FNCLCC system shows Grade 1 = 50 (20%), Grade 2 = 75 (30%) & Grade 3 = 125 (50%). NCI (Costa et al.) showed Grade 1 = 70 (28%) Grade 2 = 85 (34%) & Grade 3 = 95 (38%). Myhre Jensen showed Grade 1 = 84 (33%), Grade 98 (39%) & Grade 3 = 68 (27%). Undoubtedly, FNCLCC system is the best of all grading systems which is very well supported by statistical analysis in this study.Conclusions: FNCLCC grading system of soft tissue sarcomas is the best documented and tested system. This present study strongly recommends FNCLCC grading system of soft tissue sarcomas to be internationally accepted because the grading system has well defined criteria & so least possible chances of interobserver variability. The present study & few other previous studies highly recommend the mandatory use of FNCLCC grading system in histopathology report format.

    Evaluation of bone marrow aspirate in paediatric patients with pancytopenia: a 2 years study

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    Background: Pancytopenia is an important clinico-hematological entity, characterized by a triad of Anemia, leucopenia and thrombocytopenia. It’s not a disease entity itself but a manifestation of many serious and life-threatening diseases. The criteria for defining Pancytopenia is Hemoglobin (HGB) <9 g/dL; total leukocyte count (TLC) <4,000 / µL or absolute neutrophil count (ANC) is < 1.5x 109/ L; platelet count, <100 x 109/ L. The main objective of this study is to classify pancytopenic cases on etiological basis.Methods: A total of 750 bone marrow smears of pancytopenic patients were studied.Results: It comprised of 72 % boys & 28 % girls with the highest number of cases < 5 years of age (64%).The maximum number of cases were of ALL and Aplastic anemias.Conclusions: CBC, clinical findings and PBS provides valuable information in the workup of pancytopenic patients and help in planning additional investigations on bone marrow samples. Bone marrow evaluation is a valuable diagnostic procedure which may confirm the diagnosis of suspected cytopenias. So the take home message is a) pediatric leukemias unlike adults, usually presents with pancytopenia b) CBC+ PBS + BMA with flow cytometry can help in diagnosing majority of pancytopenias

    Effect of strength of gravitational field on the rate of chemical reactions

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    The magnitude of the rate of chemical reactions also depends on the position in the gravitational field, where a chemical reaction is being carried out. At higher gravitational field rate of reaction is greater than the rate of reaction at the lower gravitational field provided temperature and pressure are kept constant at two positions in the gravitational field. Effect of gravity on the rates of reactions has been shown by formulating the rate constants from basic theories of chemical kinetics i.e. transition state theory, collision theory, RRKM and Marcus theory in the language of the general theory of relativity. Gravitational transformation of Boltzmann constant and energy quantum levels of molecules has been developed quantum mechanically. Gravitational transformation of thermodynamic state functions has been formulated that successfully explains quasi-equilibrium existing between reactants and activated complex; at different gravitational fields. Gravitational mass dilation has been developed that explains at higher gravitational fields the transition states possess more kinetic energy to sweep translation on the reaction coordinate, resulting in the faster conversion of reactants into products. Gravitational transformation of the half-life equation shows gravitational time dilation for the half-life period of chemical reactions and thus renders the general theory of relativity and present theory are in accord with each other.Comment: 19 pages, 1 Table, 2 Figure

    Safety in the fishery sector of Pakistan: exploratory research

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    Platelet indices- evaluation of their diagnostic role in pediatric thrombocytopenias (one year study)

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    Background: Thrombocytopenias can be categorised into hypoproliferative (group I) & hyperdestructive types (group II) based on their etiology. Platelet indices (MPV, PDW, P-LCR, platelet-crit) can be used to differentiate this type of thrombocytopenias & these are simple, cost-effective, noninvasive & reliable. The main objective of this study was to evaluate the efficiency of platelet indices to differentiate hypoproductive type from hyperdestructive thrombocytopenias.Methods: Automated Hematology Analyzer Sysmex XT-2000i used to assess platelet indices. 100 Cases of thrombocytopenia & age adjusted (similar age group) controls with normal CBC & peripheral blood smears were included in the study. The gender was not taken into account as the ranges of platelet indices are almost the same for boys & girls of similar age groups.Results: The platelet indices of group I was platelet count = (51.8 ± 31.6) x103/mm, MPV = (8.5 ± 1.27) fl, PDW = (14.10 ± 1.15) fl, P-LCR = (31.90 ± 3.46)%. The platelet indices of group II was platelet count = (39.6 ± 32.7) x103/mm, MPV = (11.6 ± 2.25) fl, PDW = (15.16 ± 1.36) fl, P-LCR = (34.30 ± 2.2)%. Comparative analysis of MPV, PDW & P-LCR of group I and group II showed p value <0.05 proving it to be statistically significant.Conclusions: The combined interpretation of MPV, PDW & P-LCR by automated cell counters can be very useful parameters in differentiating thrombocytopenias due to various etiologies. Platelet indices showed inverse relationship with platelet count as they are increased in hyperdestructive type & shows linear relationship in hypoproliferative type. MPV, PDW & P-LCR can be precisely used to differentiate hyperdestructive type (ITP) from hypoproliferative type (acute leukemias, aplastic anemias). Platelet-crit & platelet large cell ratio are less sensitive parameters to differentiate these thrombocytopenias.
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