The Relationship between Lymphocytic ABCA1 Protein with IL10 and TNF-α Cytokines Followed by one period Interval Combined Exercise Training in Overweight and Obese Male Adolescents

Abstract Background: The study on rats showed that some of cytokines and proteins which were produced by macrophages and other cells, plays a critical role in regulating of ABCA1 expression. But, in this area, the study in human subjects, especially subsequent physical activity has not performed. The purpose of this study was to investigate the relationship between lymphocytic ABCA1 protein with IL-10 and TNF-α cyrokines subsequent eight weeks interval combined exercise training (ICET) among overweight and obese boy adolescents. Materials and Methods: In this semi-experimental study, 28 students (16.93±1.89 yr, 88.07±9.98 kg and 28.35±2.55 kg/m²) were randomly selected and assigned into training (n=13) and control (n=15) groups. Exercise protocol was ICET (8WK, 4 d/wk, 70 min/d).Cell hemolysis and sensitive Elisa method was used for evaluating ABAC1 protein T-student tests and Pearson correlation were used to analyze the data. Results: The survey changes of post to pre-test of ABCA1, IL-10 and TNF-α showed that there was a positive significant correlation between lymphocytic ABCA1 protein with IL-10 (r=0.43, p=0.032) and a negative significant correlation with TNF-α (r=-0.53, p=0.012) (p<0.01) after eight weeks training. Also, after exercise, ABCA1 level was significantly increased but the levels of in creased IL10 and decreased TNF-α were not significant. Conclusion: Due to the increased lymphocytic ABCA1 protein concentration and the correlation between variables following training, the results prove that TNF-α and IL-10 may have negative and positive regulatory effects on lymphocytic ABCA1 protein expression, respectively

The effects of rope training on Paraoxonase-1 enzyme, insulin resistance and lipid profiles in inactive girls

Background: Paraoxonase-1 (PON1) is one of the most important enzymes for removal of the free radicals, and the main protective factor for lipoproteins against oxidative agents. The purpose of this study was to investigate the effects of eight weeks&rsquo; rope training on paraoxonase-1 enzyme, insulin resistance and lipid profiles in inactive overweight and obese girls. Methods: This quasi-experimental study was conducted in Iranian Azarbaijan Shahid Madani University of Tabriz, from November 2016 to January 2017. In this study, 20 healthy overweight and obese in-active girls (20-25 Yr) volunteered and randomly assigned into exercise (n=10) and control (n=10) groups. Exercise protocol was rope training was 8 week for 4 day per week in 45 minute per day. Some anthropometric indexes of subjects were measured before and after exercise. A fasting blood sample was collected as pre-test and post-test, followed by 48 hours of physical inactivity to measure serum levels of PON1 enzyme, Insulin, lipid profiles and other blood variables. Analysis of the data was performed by paired and independent samples t-tests by using the SPSS software, version 20 (IBM, Armonk, NY, USA). The criterion of statistical significance was set as P<0.05. Results: The paired samples t-test results showed that after exercise intervention, in exercise group, the values of all variables (except low-density lipoprotein) were significantly changed. Also, to compare with control group, the values of PON1 enzyme (P=0.024) and maximum oxygen consumption (P=0.006) significantly increased and insulin resistance index (P=0.028), triglyceride (P=0.046) and body fat percent (P=0.001) were significantly decreased (P<0.05). Conclusion: The results of this study showed that performing rope training for 8 weeks induced positive changes in paraoxonase-1 enzyme, insulin resistance index, maximum oxygen consumption and some lipid and anthropometric indices in overweight and obese young girls. Therefore, according to these results, rope training, as an aerobic activity it can be useful for all people especially in overweight and obese to control blood fats, body composition and prevent diseases due to obesity such as cardiovascular disease.&nbsp

Study the Effect of Exercise on Bone Markers, Glycemic and Anthropometric Indices in Postmenopausal Women with Diabetes

Abstract Background: Diabetes mellitus is a common disease in human societies that dealing with its complications imposes enormous cost to the health system. The previous studies have shown that bone biochemical markers can be used for evaluation of bone metabolism in response to physical activity. The purpose of this study was to examine the effect of increasing 10-week aerobic exercise (AE) on serum osteocalcin, PTH and glycemic and anthropometric indices in postmenopausal women with type II diabetes. Materials and Methods: In this semi-experimental study, 40 postmenopausal women with type II diabetes (40-60 years) as available subjects were selected and randomly assigned into two exercise (20) and control (20) groups. Exercise protocol was AE and walking activity for 10 weeks (3d/wk, 45 to 60 min/d with 45% to 60% HRRmax intensity). Blood samples were taken before and after exercise to measure serum variables. Data were analyzed by T-test and statistical significance criterion was set as p<0.05. Results: AE makes a significant increase in osteocalcin levels and a decrease in insulin resistance index, insulin and fasting blood glucose in the experimental group (p0.05). Conclusion: Due to the favorable effects of AE on osteocalcin and glycemic indices, it seems that this training method can be recommended as a non-invasive treatment for maintaining bone density and controlling blood glucose in diabetic patients

The effect of sesamine and aerobic exercise on plasma levels of total antioxidant capacity and glutathione peroxidase in athlete men

Background: One the ways to deal with the adverse effects of oxidative stress caused by exercise activities is to use oral antioxidant supplements or to apply natural remedies. Sesamin is the most prominent lignan compound found in sesame seeds, one of the two highest sources of lignans in the human diet (the other being flax). Sesamin is catered to be a nutritional supplement that confers antioxidant and anti-inflammatory effects or possibly being an estrogen receptor modulator and fat burner. For this purpose, the present study was conducted to evaluate the effect of 10 weeks supplementation of sesamin and aerobic exercise on plasma levels of total antioxidant capacity and glutathione peroxidase in athletic men. Methods: In this quasi-experimental study, in Azarbayjan Shahid Madani University of Tabriz City from January to March of 2016 ,40 male subjects aged between 25 and 20 were randomly selected from placebo (10 subjects) and aerobic exercise (10 students), aerobic training+sesamin (10 people) and sesamin (10 people). The aerobic exercise protocol is (ten weeks / three days / 30-35 minutes). Blood samples were collected from subjects in six stages to evaluate the considered variables. Measurement of levels of antioxidant capacity and glutathione peroxidase measurements were conducted by the Antioxidant capacity and GPX assay kit (ZellBio, German). For data analysis, repeated measures of variance analysis at a significant level of 5 hundredths were used by employing SPSS software, version 20 (SPSS Inc., Chicago, IL, USA). Results: Subjects who took sesamin supplementation and performed aerobic exercise showed a significant difference in the levels of total antioxidant and glutathione peroxidase capacity in the groups (P<0.05). Also, the changes in total antioxidant and peroxide levels after interference (steps 4, 5, 6) and before interference (steps 1, 2, 3) had meaningful differences in obtained results (P=0.001). Also, the interactive effects of group and time on total antioxidant capacity and glutathione peroxidase were also significant (P=0.001). Conclusion: Aerobic exercise and supplementation of sesamin is an effective method to improve the health of mens athlete's immune system. In addition, combining supplementation with aerobic exercise can increase some of the beneficial effects of exercise during a 10-week period

The Effect of One Period of Progressive Resistance Training on Plasma Levels of Omentin-1, Insulin Resistance, Non-high Density Lipoprotein and Some cardiovascular Risk Factors in Men

Background and Objectives: Adipose tissue as an endocrine gland produces a large number of intermediate compounds that are involved in many metabolic processes. Omentin-1 as a beneficial adipokine, has attracted more attention from researchers due to its favorable effects on inflammation, glucose homeostasis, and prevention of cardiovascular disease (CVD). The aim of this study was to investigate the effect of 8 weeks of progressive resistance training on plasma levels ofomentin-1, insulin resistance, non-high density lipoprotein (non-HDL), and some cardiovascular risk factors in overweight and obese men. Methods :In this quasi-experimental study, 20 healthy overweight and obese male subjects (22.75&plusmn;1.29 years, 89.22&plusmn;13.08kg, 28.36&plusmn;3.98kg/m&sup2;), were selected as available subjects and randomly assigned to training (n=10) and control (n=10) groups. Exercise protocol included 8 weeks of resistance training (4 sessions/week, 60min/session). Blood samples were taken before and after the exercise to evaluate blood variables. Plasma omentin-1 level was measured using ELISA method. Data were analyzed by paired and independent t-tests at the significance level of p<0.05. Results: After 8 weeks of resistance training in the experimental group, the level of serum omentin-1 insignificantly increased (p=0.79), and the levels of non-HDL-c (p=0.024), TG (p=0.017), TC (p=0.032), and systolic blood pressure (p=0.002) significantly decreased. There were no significant changes in other variables. Conclusion: The results of this study showed that 8 weeks of resistance training, in spite of positive effect on some cardiovascular risk factors (non-HDL-c, triglyceride, total cholesterol), had no significant effect on omentin-1 and insulin resistance

Effects of training Pilates and Aerobic on happiness and desire for physical in inactive women

Background & Aim: Balance between mental and physical health plays an essential role in happiness and desire for physical activities in individuals. On the other hand, Pilates and aerobic exercises play a pivotal role in creating balance between mental and physical health, in a way that sport activities could improve self-satisfaction and happiness. This study aimed to evaluate the effect of eight weeks of Pilates and aerobic exercises on happiness and desire for physical activities in inactive women. Materials & Methods: This quasi-experimental research was conducted on 40 inactive women in Tabriz, Iran in 2016. Subjects were selected through random sampling and were divided into four groups of control, Pilates, aerobic, and Pilates-aerobic program. In total, the participants attended 24 60-minute Pilates and aerobic sessions (three times per week) and filled the questionnaire of happiness and desire for physical activities before and after the intervention. It is notable that the reliability of the research tool was estimated at the Cronbach&rsquo;s alpha of 0.93 and 0.87, respectively. In addition, data analysis was performed in SPSS version 20, and P-value less than 0.05 was considered statistically significant. Results: According to the results of ANOVA and Tukey&rsquo;s test, intervention caused a significant increase in both happiness and desire for physical activities in the subjects. However, there was no significant difference between the groups regarding the level of improvement. Conclusion: According to the results of the study, physical exercises and sports, specifically Pilates and aerobic exercises, are not only valuable tools for maintaining physical health, but also they have a close correlation with mental health and happiness of inactive women. Therefore, it is suggested that these types of activities be applied as a solution for creating and increasing a good mood in women&rsquo;s society

Effect of an Incremental Interval Endurance Rope-Training Program on Antioxidant Biomarkers and Oxidative Stress in Non-Active Women

Background & Aim: Aerobic exercises are recommended as an important technique to control and prevent cardiovascular diseases and metabolic disorders. Therefore, this study aimed to evaluate the effect of an incremental interval endurance rope-training program on antioxidant biomarkers and oxidative stress in non-active women. Materials & Methods: This quasi-experimental research was conducted on non-active female subjects (overweight and obese) at the age range of 20-30 years. In total, 20 eligible participants were selected via random sampling and divided into two control and intervention groups of 10. The training program included eight weeks (four 45-minute sessions per week) of incremental rope training. Data analysis was performed in SPSS version 20 using dependent and independent t-tests at the significance level of 0.05. Results: The results of dependent t-test showed a significant increase in the level of superoxide dismutase enzyme, total antioxidant capacity, and glutathione peroxidase, compared to the pre-test state of the subjects (P0.05). Moreover, results of independent t-test demonstrated a non-significant increase in the total antioxidant capacity and glutathione peroxidase in subjects of the intervention group, compared to the control group. On the other hand, there was a significant increase and decrease in superoxide dismutase and malondialdehyde, respectively (P<0.05). Conclusion: According to the results of the study, rope training increased antioxidant defense and decreased oxidative damage and lipid peroxidation. Therefore, it seems that this type of training can prevent cardiovascular diseases in overweight and obese individuals