A Comparative Analysis of Wound Closure Techniques in Uncomplicated Open Inguinal Hernia Surgery: Sutures vs. Skin Staplers

  Objective: This study compared the results of wound closure with skin staplers and traditional sutures in uncomplicated open inguinal hernia surgery. Methods: An 18-month prospective cohort study was carried out in a tertiary care facility. Patients (n = 100) who met the eligibility requirements were randomly assigned to one of two groups: suture (n = 50) or skin stapler (n = 50). We evaluated wound infection rates, wound healing times, postoperative pain levels, and aesthetic results. Chi-squared tests, t-tests, and Mann-Whitney U tests were used in the statistical analysis. Results: Skin staplers demonstrated lower wound infection rates (2% vs. 10%) and faster wound healing (10.5 ± 1.8 days vs. 14.2 ± 2.1 days) compared to sutures. Postoperative pain scores were consistently lower in the skin stapler group at 24 hours (2.4 ± 0.8 vs. 3.7 ± 1.2), 1 week (1.4 ± 0.6 vs. 2.1 ± 0.9), and 4 weeks (0.6 ± 0.3 vs. 0.9 ± 0.4) post-surgery. Skin staplers with a higher percentage of "excellent" results (54% vs. 14%) had better cosmetic results. Conclusion: In uncomplicated open inguinal hernia surgery, skin staplers are superior to conventional sutures in terms of lower wound infection rates, quicker wound healing, decreased postoperative pain, and enhanced cosmetic results. Surgeons’ ought to think about how skin staplers could improve patient satisfaction and outcomes. Inguinal hernia surgery wound closure techniques may be improved with further study and practical practice

The Role of Serum Albumin Level as a Predictor of Post-Operative Outcomes Following Emergency Exploratory Laparotomy: A Prospective Study

  Background: An emergency exploratory laparotomy is a crucial surgical technique used to treat abdominal diseases that pose a risk to life. Optimizing patient treatment in this situation requires the identification of variables that predict post-operative results. A widely available biomarker called serum albumin has been suggested as a potential predictor of mortality, length of hospital stay, and post-operative problems. Methods: 100 patients who underwent emergency exploratory laparotomies between January 2021 and June 2022 were the subject of a prospective study. Clinical information was gathered along with measurements of the serum albumin levels prior to surgery. Post-operative outcomes were recorded, including complications, length of stay in the hospital, and mortality. Results: When compared to patients with normal albumin levels, those with low serum albumin levels (3.5 g/dL) had a greater incidence of post-operative problems (62% vs. 38%, p <0.05) and longer hospital admissions (12.7 days vs. 8.4 days, p< 0.001). Additionally, hypoalbuminemic individuals had considerably greater mortality (16% vs. 6%, p <0.05). Conclusion: In emergency exploratory laparotomies, pre-operative serum albumin level is a useful predictor of post-operative outcomes. Increased complications, extended hospital stays, and greater mortality rates are all linked to hypoalbuminemia. The therapeutic significance of serum albumin evaluation for risk stratification, preoperative planning, and well-informed decision-making in this complex surgical scenario is highlighted by these findings. To validate these findings and investigate potential strategies to enhance outcomes, more study is required

Comparative Study on the Efficacy of Single-Layer vs. Double-Layer Small Gut Anastomosis in Patients Admitted to a Tertiary Care Center

Background: For a number of gastrointestinal diseases, small bowel resection with anastomosis is a common surgical treatment. The choice of anastomotic technique, specifically between single-layer and double-layer approaches, is still up for debate. Methods: Between December 2020 and June 2022, 50 patients who had small intestinal resections participated in this prospective observational study. Single-layer anastomosis (n = 28) and double-layer anastomosis (n = 22) groups of patients were created. Anastomotic leaks, postoperative complications, hospital stay, bowel function recovery, and patient satisfaction were all included in the outcome measures. Chi-squared and t-tests were utilized in the statistical analysis. Results: There was no statistically significant difference between the anastomotic leak rates of 7.1% in the single-layer group and 4.5% in the double-layer group (p > 0.05). Similar postoperative problems, hospital stays (averaged 6 days), recovery times for bowel function (averaged 3 days), and patient satisfaction levels were seen in both groups. Conclusion: Current study shows that single-layer and double-layer techniques yield equivalent results in small bowel resection and anastomosis. The fact that these procedures have similar anastomotic leaks, postoperative complications, hospital stays, and bowel function restoration times suggests that the surgeon's preference and experience may influence the decision. Both groups have great patient satisfaction, suggesting that the anastomotic approach has little to no impact on patient treatment

PREVALENCE OF THYROID DISEASE ALONG WITH BREAST CANCER

Some authors have observed a higher prevalence of AITDs in BC patients compared to age-matched controls; thus, this association is not new. Some studies have found that the presence of TPO antibodies is associated with a significantly better outcome among BC patients and that this improvement is comparable to that seen with other prognostic indices such as axillary node status and tumor size, though the exact significance of this association is unclear.Therefore, the purpose of this study was to assess TD with BC in relation to the female population. All cases that meet the inclusion criteria will be considered after receiving approval from the IEC. The demographic characteristics, clinical, medical, social, and family H/O were documented using a semi-structured, standardized, and pre-validated case record. In addition, a comprehensive and systematic evaluation was conducted on all patients diagnosed with breast cancer. This evaluation included clinical, radiological, and laboratory screenings, involving a total of 69 patients. In our study, we found that the occurrence of abnormal TFT results was more frequently linked to cases of BC in comparison to the control group. The data was analyzed using the Chi-square test, which yielded a highly statistically significant result with a p-value of 0.0006. The findings of our study demonstrate a substantial correlation between BC and TD. Further investigation is necessary to validate this correlation