On B_s -> mu+ mu- and Cold Dark Matter Scattering in the MSSM with Non-Universal Higgs Masses

We show that present experimental constraints on B_s -> mu+ mu- decay and the CDMS upper limit on the cold dark matter elastic scattering cross section already have significant impact on the parameter space of the minimal supersymmetric extension of the Standard Model (MSSM) with non-universal supersymmetry-breaking scalar masses for the Higgs multiplets (NUHM). The relaxation of scalar universality in the MSSM allows the possibility of a relatively light mass M_A for the pseudoscalar Higgs boson. The present upper limit on B_s -> mu+ mu- already excludes much of the scope for this possibility in the NUHM, in contrast to the constrained MSSM with universal scalar masses (CMSSM), where B_s -> mu+ mu- decay does not exclude any ranges of parameters not already excluded by b -> s \gamma decay. Cold dark matter scattering is also enhanced for small M_A, but the impact of present upper limit on B_s -> mu+ mu- on the NUHM parameter space is in many cases greater than that of the CDMS scattering limit, particularly at large tanb.Comment: 17 pages, 14 eps figure

Spatially distinct and metabolically active membrane domain in mycobacteria

Protected from host immune attack and antibiotic penetration by their unique cell envelope, mycobacterial pathogens cause devastating human diseases such as tuberculosis. Seamless coordination of cell growth with cell envelope elongation at the pole maintains this barrier. Unraveling this spatiotemporal regulation is a potential strategy for controlling mycobacterial infections. Our biochemical analysis previously revealed two functionally distinct membrane fractions in Mycobacterium smegmatis cell lysates: plasma membrane tightly associated with the cell wall (PM-CW) and a distinct fraction of pure membrane free of cell wall components (PMf). To provide further insight into the functions of these membrane fractions, we took the approach of comparative proteomics and identified more than 300 proteins specifically associated with the PMf, including essential enzymes involved in cell envelope synthesis such as a mannosyltransferase, Ppm1, and a galactosyltransferase, GlfT2. Furthermore, comparative lipidomics revealed the distinct lipid composition of the PMf, with specific association of key cell envelope biosynthetic precursors. Live-imaging fluorescence microscopy visualized the PMf as patches of membrane spatially distinct from the PM-CW and notably enriched in the pole of the growing cells. Taken together, our study provides the basis for assigning the PMf as a spatiotemporally distinct and metabolically active membrane domain involved in cell envelope biogenesis

General Analysis of Antideuteron Searches for Dark Matter

Low energy cosmic ray antideuterons provide a unique low background channel for indirect detection of dark matter. We compute the cosmic ray flux of antideuterons from hadronic annihilations of dark matter for various Standard Model final states and determine the mass reach of two future experiments (AMS-02 and GAPS) designed to greatly increase the sensitivity of antideuteron detection over current bounds. We consider generic models of scalar, fermion, and massive vector bosons as thermal dark matter, describe their basic features relevant to direct and indirect detection, and discuss the implications of direct detection bounds on models of dark matter as a thermal relic. We also consider specific dark matter candidates and assess their potential for detection via antideuterons from their hadronic annihilation channels. Since the dark matter mass reach of the GAPS experiment can be well above 100 GeV, we find that antideuterons can be a good indirect detection channel for a variety of thermal relic electroweak scale dark matter candidates, even when the rate for direct detection is highly suppressed.Comment: 44 pages, 15 Figure

Acceptance of Simulated Oral Rabies Vaccine Baits by Urban Raccoons

In summer 1986, a study was conducted to evaluate raccoon (Procyon lotor) acceptance of oral baits that could be used for rabies vaccination, One thousand wax-coated sponge bait cubes were filled with 5 mg of a seromarker (iophenoxic acid), placed in polyethylene bags, and hand-distributed in an 80 ha area within an urban National Park in Washington, D.C. (USA), After 3 wk, target and nontarget animals were trapped and blood samples collected to evaluate bait uptake. Thirty-three of 52 (63%) raccoons had elevated blood iodine levels indicating they had eaten at least one bait, 13 (25%) were negative, and six (12%) had marginal values, These results indicate that sponge baits hand-placed at a density of 12,4/ha can reach a significant proportion of an urban raccoon population. Implications for oral rabies vaccination of raccoons are discussed

What if Supersymmetry Breaking Unifies beyond the GUT Scale?

We study models in which soft supersymmetry-breaking parameters of the MSSM become universal at some unification scale, $M_{in}$, above the GUT scale, \mgut. We assume that the scalar masses and gaugino masses have common values, $m_0$ and $m_{1/2}$ respectively, at $M_{in}$. We use the renormalization-group equations of the minimal supersymmetric SU(5) GUT to evaluate their evolutions down to \mgut, studying their dependences on the unknown parameters of the SU(5) superpotential. After displaying some generic examples of the evolutions of the soft supersymmetry-breaking parameters, we discuss the effects on physical sparticle masses in some specific examples. We note, for example, that near-degeneracy between the lightest neutralino and the lighter stau is progressively disfavoured as $M_{in}$ increases. This has the consequence, as we show in $(m_{1/2}, m_0)$ planes for several different values of $\tan \beta$, that the stau coannihilation region shrinks as $M_{in}$ increases, and we delineate the regions of the $(M_{in}, \tan \beta)$ plane where it is absent altogether. Moreover, as $M_{in}$ increases, the focus-point region recedes to larger values of $m_0$ for any fixed $\tan \beta$ and $m_{1/2}$. We conclude that the regions of the $(m_{1/2}, m_0)$ plane that are commonly favoured in phenomenological analyses tend to disappear at large $M_{in}$.Comment: 24 pages with 11 eps figures; references added, some figures corrected, discussion extended and figure added; version to appear in EPJ

Revisiting the Higgs Mass and Dark Matter in the CMSSM

Taking into account the available accelerator and astrophysical constraints, the mass of the lightest neutral Higgs boson h in the minimal supersymmetric extension of the Standard Model with universal soft supersymmetry-breaking masses (CMSSM) has been estimated to lie between 114 and ~ 130 GeV. Recent data from ATLAS and CMS hint that m_h ~ 125 GeV, though m_h ~ 119 GeV may still be a possibility. Here we study the consequences for the parameters of the CMSSM and direct dark matter detection if the Higgs hint is confirmed, focusing on the strips in the (m_1/2, m_0) planes for different tan beta and A_0 where the relic density of the lightest neutralino chi falls within the range of the cosmological cold dark matter density allowed by WMAP and other experiments. We find that if m_h ~ 125 GeV focus-point strips would be disfavoured, as would the low-tan beta stau-chi and stop -chi coannihilation strips, whereas the stau-chi coannihilation strip at large tan beta and A_0 > 0 would be favoured, together with its extension to a funnel where rapid annihilation via direct-channel H/A poles dominates. On the other hand, if m_h ~ 119 GeV more options would be open. We give parametrizations of WMAP strips with large tan beta and fixed A_0/m_0 > 0 that include portions compatible with m_h = 125 GeV, and present predictions for spin-independent elastic dark matter scattering along these strips. These are generally low for models compatible with m_h = 125 GeV, whereas the XENON100 experiment already excludes some portions of strips where m_h is smaller.Comment: 24 pages, 9 figure

Phenomenology of GUT-less Supersymmetry Breaking

We study models in which supersymmetry breaking appears at an intermediate scale, M_{in}, below the GUT scale. We assume that the soft supersymmetry-breaking parameters of the MSSM are universal at M_{in}, and analyze the morphology of the constraints from cosmology and collider experiments on the allowed regions of parameter space as M_{in} is reduced from the GUT scale. We present separate analyses of the (m_{1/2},m_0) planes for tan(beta)=10 and tan(beta)=50, as well as a discussion of non-zero trilinear couplings, A_0. Specific scenarios where the gaugino and scalar masses appear to be universal below the GUT scale have been found in mirage-mediation models, which we also address here. We demand that the lightest neutralino be the LSP, and that the relic neutralino density not conflict with measurements by WMAP and other observations. At moderate values of M_{in}, we find that the allowed regions of the (m_{1/2},m_0) plane are squeezed by the requirements of electroweak symmetry breaking and that the lightest neutralino be the LSP, whereas the constraint on the relic density is less severe. At very low M_{in}, the electroweak vacuum conditions become the dominant constraint, and a secondary source of astrophysical cold dark matter would be necessary to explain the measured relic density for nearly all values of the soft SUSY-breaking parameters and tan(beta). We calculate the neutralino-nucleon cross sections for viable scenarios and compare them with the present and projected limits from direct dark matter searches.Comment: 35 pages, 9 figures; typos corrected, references adde

Constrained Supersymmetric Flipped SU(5) GUT Phenomenology

We explore the phenomenology of the minimal supersymmetric flipped SU(5) GUT model (CFSU(5)), whose soft supersymmetry-breaking (SSB) mass parameters are constrained to be universal at some input scale, $M_{in}$, above the GUT scale, $M_{GUT}$. We analyze the parameter space of CFSU(5) assuming that the lightest supersymmetric particle (LSP) provides the cosmological cold dark matter, paying careful attention to the matching of parameters at the GUT scale. We first display some specific examples of the evolutions of the SSB parameters that exhibit some generic features. Specifically, we note that the relationship between the masses of the lightest neutralino and the lighter stau is sensitive to $M_{in}$, as is the relationship between the neutralino mass and the masses of the heavier Higgs bosons. For these reasons, prominent features in generic $(m_{1/2}, m_0)$ planes such as coannihilation strips and rapid-annihilation funnels are also sensitive to $M_{in}$, as we illustrate for several cases with tan(beta)=10 and 55. However, these features do not necessarily disappear at large $M_{in}$, unlike the case in the minimal conventional SU(5) GUT. Our results are relatively insensitive to neutrino masses.Comment: 23 pages, 8 figures; (v2) added explanations and corrected typos, version to appear in EPJ

Galactic-Centre Gamma Rays in CMSSM Dark Matter Scenarios

We study the production of gamma rays via LSP annihilations in the core of the Galaxy as a possible experimental signature of the constrained minimal supersymmetric extension of the Standard Model (CMSSM), in which supersymmetry-breaking parameters are assumed to be universal at the GUT scale, assuming also that the LSP is the lightest neutralino chi. The part of the CMSSM parameter space that is compatible with the measured astrophysical density of cold dark matter is known to include a stau_1 - chi coannihilation strip, a focus-point strip where chi has an enhanced Higgsino component, and a funnel at large tanb where the annihilation rate is enhanced by the poles of nearby heavy MSSM Higgs bosons, A/H. We calculate the total annihilation rates, the fractions of annihilations into different Standard Model final states and the resulting fluxes of gamma rays for CMSSM scenarios along these strips. We observe that typical annihilation rates are much smaller in the coannihilation strip for tanb = 10 than along the focus-point strip or for tanb = 55, and that the annihilation branching ratios differ greatly between the different dark matter strips. Whereas the current Fermi-LAT data are not sensitive to any of the CMSSM scenarios studied, and the calculated gamma-ray fluxes are probably unobservably low along the coannihilation strip for tanb = 10, we find that substantial portions of the focus-point strips and rapid-annihilation funnel regions could be pressured by several more years of Fermi-LAT data, if understanding of the astrophysical background and/or systematic uncertainties can be improved in parallel.Comment: 33 pages, 12 figures, comments and references added, version to appear in JCA

Dynamical supersymmetry breaking in a superstring inspired model

We present a dilaton dominated scenario for supersymmetry breaking in a recently constructed realistic superstring inspired model with an anomalous U(1) symmetry. Supersymmetry is broken via gaugino condensation due to a confining SU(Nc) gauge group in the hidden sector. In particular, we find that by imposing on the model the phenomenological constraint of the absence of observed flavor changing neutral currents, there is a range of parameters related to the hidden sector and the Kahler potential for which we obtain a low energy spectrum consistent with present experimental bounds. As an illustrative example, we derive the low energy spectrum of a specific model. We find that the LSP is the lightest neutralino with a mass of 53 GeV and the lightest Higgs has a mass of 104 GeV.Comment: 13 page