Muscle trematode infection of alien cyprinids in the basin of the Middle Ob (Sibiria, Russia)

The book represents proceedings of Sixth International Symposium “Invasion of Alien Species in Holarctic. Borok -VI” (11 Oct. – 15 Oct. 2021, Borok – Uglich, Russia). The wide spectrum of problems related to appearance and spread of invasive plants and animals is discussed. The book may be interested for specialists in many fields, such as limnologists, hydrobiologists, ecologists, botanists, zoologists, geographers, managers of dealing with nature preservation and fisheries

NanoSat MO Framework: Enabling AI Apps for Earth Observation

Following the success of the first Phi-Sat mission, in 2020, the European Space Agency (ESA) announced the opportunity to present CubeSat-based ideas for the Phi-Sat-2 mission as part of its initiative to promote the development of radically innovative technologies such as Artificial Intelligence (AI) capabilities onboard Earth Observation (EO) missions. Open Cosmos and CGI submitted a joint proposal for the Phi-Sat-2 mission idea, which takes advantage of the latest research and developments in the European ecosystem. The proposed mission idea is a game-changing EO CubeSat capable of running AI Apps that can be developed, easily deployed on the spacecraft and updated during flight operations. The AI Apps can be operated from ground using a simple user interface. This approach allows continuous improvement of the AI model parameters using the very same images acquired by the satellite. The mission takes advantage of the latest research for mission operations of CubeSats and use the NanoSat MO Framework, a framework for small satellites that allows software to be deployed in space as simple Apps, in a similar fashion to Android apps. This framework was previously demonstrated in ESA’s OPS-SAT mission, and supports the orchestration of on-board Apps. It fully decouples the App features from the underlying on-board hardware via an abstraction layer API in the form of services. Additionally, it includes a Software Development Kit with demo Apps, development tools, and tutorials to facilitate the development of Apps. By decoupling the data platform from the Apps, it is possible to distribute the development of specialized AI Apps to different partners within the Phi-Sat-2 mission consortium. The mission will include a set of default AI Apps that will be able to do vessel detection, forest monitoring, and roadmap transformation from satellite imagery. The framework allows more than just the set of default Apps and so, third-party Apps can be included on later stages of the mission lifecycle. This paper will present the NanoSat MO Framework, introduce the AI Apps that are part of the Phi-Sat-2 mission, and how the free and open-source framework enables the creation of software-defined satellite missions via on-board Apps

The World Largest Focus of the Opisthorchiasis in the Ob-Irtysh Basin, Russia, Caused by <em>Opisthorchis felineus</em>

The world’s largest focus of opisthorchiasis caused by cat fluke Opisthorchis felineus Rivolta, 1884, is associated with the Ob-Irtysh basin (Russia). The chapter provides data on the history of discovery and the study of opisthorchiasis. Features of the morphology and life cycle of O. felineus are described. Data on the infection of intermediate hosts (mollusks and cyprinids fish) are provided. Species of fish that have important epizootological significance are indicated. The incidence of opisthorchiasis in the people of different age and social groups, clinical manifestations, pathogenesis, and complications is discussed. The climatic and social factors that contribute to maintaining the focus of opisthorchiasis are described. The measures of personal and social prevention of the people are given

The ESA ΦSat-2 Mission: An A.I Enhanced Multispectral CubeSat for Earth Observation

As part of an initiative to promote the development and implementation of innovative technologies on-board Earth Observation (EO) missions, the European Space Agency (ESA) kicked off the first Φsat related activities in 2018 with the aim of enhancing the already ongoing FSSCAT project with Artificial Intelligence (AI). The selected Φsat-2 concept will provide a combination of on-board processing capabilities (including AI) and a medium to high resolution multispectral instrument from Visible to Near Infra-Red (VIS/NIR) able to acquire 8 bands (7 + Panchromatic) provided by SIMERA SENSE Europe (BE). These resources will be made available to a series of dedicated applications that will run on-board the spacecraft. The mission prime is Open Cosmos (UK), supported by CGI (IT) to coordinate the payload operations for at least 12 months after LEOP and commissioning phase. During the nominal phase the various AI applications will be fine-tuned after the on-ground training and then routinely run. A series of AI applications that could be potentially embarked are under development. The first one is called SAT2MAP and is expected to autonomously detect streets from acquired images. It is developed by CGI (IT). The second AI application is an enhancement of the Φsat-1 cloud detection experiment, able to prioritize data to be downloaded to ground, based on standard cloud coverage and new concentration measurements. It is developed by KP Labs (PL) and it is based on a U-Ne. This application will mainly act as an on-board service for the other applications, relieving them of the task of assessing the presence of the clouds. The Autonomous Vessel Awareness application aims to detect and classify various vessel types in the maritime domain. This would enable a reduced amount of data to be downloaded (only image patches including the vessel) improving the response time for final users (e.g maritime authorities). In this case the AI technique used is a combination of Single Image Super resolution (SRCNN) and Yolo-based Convoluted Neural Network (CNN). The Deep Compression application generically reduces the amount of data to be downloaded to ground with limited information loss. The image is compressed on-board and then reconstructed on ground by means of a decoder. It can achieve a compression rate of about 7 per band. It is based on the use of a Convolutional Auto Encoder (CAE). Two more AI applications will be selected by ESA through a dedicated challenge open to institutions, Agencies and industries that will be run in the first half of 2023. The Φsat-2 mission successfully passed the CDR phase at the end of 2022 aiming for a launch in 2024

Invertebrates of Siberia, a potential source of animal protein for innovative food production. 1. The keelback slugs (Gastropoda: Limacidae)

The use of terrestrial invertebrates occurring in Siberia as a source of nutrients is an innovative form of new quality food production in North Asia. The species available for this production should be qualified by necessary criteria; for example, they should be common in the region and easily obtainable, free from restriction or prohibition as rare or protected species, adapted to regional environmental conditions, and their bodies should be free from toxins and allergens. They should also be unpretentious in terms of housing, consumption of cheap and suitable feed which provides a satisfactory increase in biomass and contains necessary nutrients in the required ratio. Several local species of terrestrial molluscs and insects fit these criteria and have been were selected as model species, such as the yellow slug Limacus flavus (Linnaeus, 1758) which has been studied in detail. Individuals of this slug were collected from a subterranean vegetable store in the city of Novosibirsk, and reared for 5 months under laboratory conditions with different lighting, humidity and temperature. Standard vegetables for winter storage, carrot, cabbage and potato (the preferred ingredient), were provided to the slugs. The most effective factors for the development of body weight and size of the slugs were registered in the dark under moderate humidity and temperature. Average weight and length of slugs at the beginning of the experiment in March 2022 were 0.62 gram and 3.42 mm, and at the end of the experiment in August 2022 were 3.67 gram and 5.76 mm (respectively x 5.9 and x 1.7). Therefore, basement and underground cold premises lacking constant lighting and provided with potato waste as a feeding substrate appear to be optimal for raising and rearing this slug species; naturally this would be of particular interest for food production in regions with cold climate conditions

Radiation and the Risk of Chronic Lymphocytic and Other Leukemias among Chornobyl Cleanup Workers

Background: Risks of most types of leukemia from exposure to acute high doses of ionizing radiation are well known, but risks associated with protracted exposures, as well as associations between radiation and chronic lymphocytic leukemia (CLL), are not clear.
 Objectives: We estimated relative risks of CLL and non-CLL from protracted exposures to low-dose ionizing radiation.
 Methods: A nested case–control study was conducted in a cohort of 110,645 Ukrainian cleanup workers of the 1986 Chornobyl nuclear power plant accident. Cases of incident leukemia diagnosed in 1986–2006 were confirmed by a panel of expert hematologists/hematopathologists. Controls were matched to cases on place of residence and year of birth. We estimated individual bone marrow radiation doses by the Realistic Analytical Dose Reconstruction with Uncertainty Estimation (RADRUE) method. We then used a conditional logistic regression model to estimate excess relative risk of leukemia per gray (ERR/Gy) of radiation dose.
 Results: We found a significant linear dose response for all leukemia [137 cases, ERR/Gy = 1.26 (95% CI: 0.03, 3.58]. There were nonsignificant positive dose responses for both CLL and non-CLL (ERR/Gy = 0.76 and 1.87, respectively). In our primary analysis excluding 20 cases with direct in-person interviews less than 2 years from start of chemotherapy with an anomalous finding of ERR/Gy = –0.47 (95% CI: less than –0.47, 1.02), the ERR/Gy for the remaining 117 cases was 2.38 (95% CI: 0.49, 5.87). For CLL, the ERR/Gy was 2.58 (95% CI: 0.02, 8.43), and for non-CLL, ERR/Gy was 2.21 (95% CI: 0.05, 7.61). Altogether, 16% of leukemia cases (18% of CLL, 15% of non-CLL) were attributed to radiation exposure.
 Conclusions: Exposure to low doses and to low dose-rates of radiation from post-Chornobyl cleanup work was associated with a significant increase in risk of leukemia, which was statistically consistent with estimates for the Japanese atomic bomb survivors. Based on the primary analysis, we conclude that CLL and non-CLL are both radiosensitive.

The Origin of the Variola Virus

The question of the origin of smallpox, one of the major menaces to humankind, is a constant concern for the scientific community. Smallpox is caused by the agent referred to as the variola virus (VARV), which belongs to the genus Orthopoxvirus. In the last century, smallpox was declared eradicated from the human community; however, the mechanisms responsible for the emergence of new dangerous pathogens have yet to be unraveled. Evolutionary analyses of the molecular biological genomic data of various orthopoxviruses, involving a wide range of epidemiological and historical information about smallpox, have made it possible to date the emergence of VARV. Comparisons of the VARV genome to the genomes of the most closely related orthopoxviruses and the examination of the distribution their natural hosts’ ranges suggest that VARV emerged 3000 to 4000 years ago in the east of the African continent. The VARV evolution rate has been estimated to be approximately 2 × 10−6 substitutions/site/year for the central conserved genomic region and 4 × 10−6 substitutions/site/year for the synonymous substitutions in the genome. Presumably, the introduction of camels to Africa and the concurrent changes to the climate were the particular factors that triggered the divergent evolution of a cowpox-like ancestral virus and thereby led to the emergence of VARV

An Update of Orthopoxvirus Molecular Evolution

Although variola virus (VARV) has been eradicated through widespread vaccination, other orthopoxviruses pathogenic for humans circulate in nature. Recently, new orthopoxviruses, including some able to infect humans, have been found and their complete genomes have been sequenced. Questions about the orthopoxvirus mutation rate and the emergence of new threats to humankind as a result of the evolution of circulating orthopoxviruses remain open. Based on contemporary data on ancient VARV DNA and DNA of new orthopoxvirus species, an analysis of the molecular evolution of orthopoxviruses was carried out and the timescale of their emergence was estimated. It was calculated that the orthopoxviruses of the Old and New Worlds separated approximately 40,000 years ago; the recently discovered Akhmeta virus and Alaskapox virus separated from other orthopoxviruses approximately 10,000–20,000 years ago; the rest of modern orthopoxvirus species originated from 1700 to 6000 years ago, with the exception of VARV, which emerged in approximately 300 AD. Later, there was a separation of genetic variants of some orthopoxvirus species, so the monkeypox virus West African subtype originated approximately 600 years ago, and the VARV minor alastrim subtype emerged approximately 300 years ago