Raditive decay of single charmed baryons

The electromagnetic transitions between ($J^{P}={3/2}^{+}$) and ($J^{P}={1/2}^{+}$) baryons are important decay modes to observe new hadronic states experimentally. For the estimation of these transitions widths, we employ a non-relativistic quark potential model description with color coulomb plus linear confinement potential. Such a description has been employed to compute the ground state masses and magnetic moments of the single heavy flavor baryons. The magnetic moments of the baryons are obtained using the spin-flavor structure of the constituting quark composition of the baryon. Here, we also define an effective constituent mass of the quarks (ecqm) by taking into account the binding effects of the quarks within the baryon. The radiative transition widths are computed in terms of the magnetic moments of the baryon and the photon energy. Our results are compared with other theoretical models.Comment: 06 Pages, Presented at XVIII DAE-BRNS symposium on High energy Physics, Banaras Hindu University, Varansi, INDI

Overlaying control mechanism for solar PV inverters in the LV distribution network

Increasing penetration of distributed renewable energy sources in LV grid leads to a number of power quality challenges. Meanwhile, changes in recent renewable energy-related grid codes foresee the massive introduction of remotely controllable inverters in the LV grid. In this paper, the future grid scenario is taken under consideration, thus proposing a solution for overvoltage problem while taking advantage of such controllable inverters. The paper discusses a novel approach to mitigate overvoltage problem by integrating the concept of P–V droop control into a cyber-physical paradigm. The proposed approach introduces a parameter, referred as virtual maximum power point that enables the proposed solution to mitigate overvoltage problem only by using local measurements. Above all, the proposed approach prevents any new hardware-related changes in the inverters. This paper simulates the proposed approach using a co-simulation model. However, to speed up the field implementation of the proposed approach, laboratory experiments were conducted and the solutions for the challenges in real-life implementation, including ICT-related challenges, are developed. Lastly, this paper discusses about the outcomes of the proposed approach in the light of both the theory and practical. In addition to the proposed overvoltage mitigation solution, the possibilities of using the controllable inverters for additional network services are also discussed

Microsatellite based genetic variation among the buffalo breed populations in Pakistan

Introduction: Eight microsatellite loci were used to define genetic diversity among five native water buffalo breeds in Pakistan. Material and Methods: Blood samples (10 mL) from 25 buffaloes of each of the Nili, Ravi, Nili-Ravi, Kundhi, and Azi-Kheli breeds were collected aseptically from the jugular vein into 50 ml Falcon tubes containing 200 µl of 0.5 M EDTA. The phenol-chloroform method was used to extract DNA and the regions were amplified for microsatellite analysis. The eight microsatellite markers ETH10, INRA005, ILSTS029, ILSTS033, ILSTS049, ILSTS052, ETH225, and CSSM66 were analysed. Results: The effective number of alleles across all loci was as usual lower than the observed values with a mean value of 2.52 alleles per locus. The overall allele frequency varied from 0.0041 for alleles B, I, and J over respective loci ILSTS052, INRA005, and ILSTS029 to 0.80 for allele H over locus ILSTS029. The average observed and expected heterozygosity values across all polymorphic loci in all studied buffalo breeds were 0.43 and 0.53, respectively. The overall value for polymorphic information content of considered microsatellite markers was 0.53, suggesting their appropriateness for genetic diversity analysis in buffalo. The mean Fis value was 0.13 and all loci except ILSTS049 were found significantly deviated from HWE, most likely due to nonrandom breeding. The five buffalo populations were genetically less diverse as indicated by a small mean Fst value (0.07). The average gene flow (Nm) indicative for population migration was calculated as 3.31. Nei’s original measures of genetic distance (Ds) revealed ancient divergence of the Nili and Azi-Kheli breeds (Ds = 0.1747) and recent divergence of the Nili and Ravi breeds (Ds = 0.0374). Conclusion: These estimates of genetic diversity were seen to coincide with phenotypic differentiation among the studied buffalo breeds. The present study reports the first microsatellite marker-based genetic diversity analysis in Pakistani buffalo breeds, and might facilitate similar studies in other livestock breeds of Pakistan

Pharmacoinformatics approaches in the discovery of drug-like antimicrobials of plant origin

Medicinal plants have served as an important source for addressing the ailments of humans and animals alike. The emergence of advanced technologies in the field of drug discovery and development has helped in isolating various bioactive phytochemicals and developing them as drugs. Owing to their significant pharmacological benefits and minimum adverse effects, they not only serve as good candidates for therapeutics themselves but also help in the identification and development of related drug like molecules against various metabolic and infectious diseases. The ever-increasing diversity, severity and incidence of infectious diseases has resulted in an exaggerated mortality and morbidity levels. Geno-proteomic mutations in microbes, irrational prescribing of antibiotics, antimicrobial resistance and human population explosion, all call for continuous efforts to discover and develop alternated therapeutic options against the microbes. This review article describes the pharmacoinformatics tools and methods which are currently used in the discovery of bioactive phytochemicals, thus making the process more efficient and effective. The pharmacological aspects of the drug discovery and development process have also been reviewed with reference to the in silico activities. Communicated by Ramaswamy H. Sarma. © 2021 Informa UK Limited, trading as Taylor & Francis Group

Usability of metadata analysis of goat genetic resources among five countries from Africa, Asia and Europe: Metadata analysis of goat genetic

Abstract. Goats play a variety of roles all around the globe due to their capability to acclimatize different environmental conditions quite quickly since they have been regarded as one of the first sets of animals domesticated by the human. Even though domestic goats harbor precious genetic materials, research funding among developing countries is a major drawback for thorough study on them. Therefore, microsatellite markers seem to be affordable and informative. Genotypic data from different goat breeds across five countries (Nigeria, South Africa, Pakistan, France and Spain) was generated using eleven microsatellite markers for a comparative study in order to evaluate the usefulness of the available data for genetic characterization and identify the shortcomings of meta-analyses for combined data. The mean number of alleles (MNA) per population range from 6.44±2.83 alleles for Spanish to 10.25±0.96 for Pakistani goats, with an overall mean of 13.55±7.28. Observed heterozygosity (Ho) ranges from 0.61±0.02 to 0.83±0.01 for Spanish goats and Pakistani goats, respectively with an overall mean of 0.65. Ho of the markers used ranged from 0.569 (INRA5) to 0.793 (MM12). Highest and least polymorphic information content (PIC) was observed in loci MM12 (0.925) and MAF209 (0.489), respectively. All the populations showed significant change from Hardy-Weinberg equilibrium (P>0.05) indicating a low level of inbreeding. The genetic distance of each country’s goat populations ranged from 0.151 to 4.245. The highest genetic distance (4.245) was observed between Spanish and Pakistani goats while the lowest were observed between Spanish and French goats. Spanish and French goats are from a common ancestor while South African, Nigerian and Pakistani goats came from another ancestor or cluster. A lot of genetic admixture in the Nigerian ecotypes has been observed whereas France and Saudi Arabian breeds have been subjected to high amount of selection pressure