A simple automated system for the routine production of 99mTc by methyl-ethyl-ketone extraction

A relatively simple, automated system for the rapid, efficient and safe routine production of 99mTcM from 99Mo03 by the methyl-ethyl-ketone (MEK) extraction technique is described. The 4 phases of the extraction process - bubbling of air, phase separation, drawing off of 99mTc in MEK, and evaporation to dryness, are controlled by an automatic timer, suction-pressure pump and solenoid switches. The eluate was found to contain neither bacterial organisms or pyrogens nor significant levels of alumina and radio-isotopic impurities. With this system it is possible to make use of locally produced 99Mo, even of low specific activity for the routine production of 99mlc in any concentration required.S. Afr. Med. J., 48, 998 (1974)