Pregnancy with autoimmune hepatitis

AIM: The aim of this study was to review our experience with gestations in autoimmune hepatitis patients. BACKGROUND: There are only limited data describing pregnancy in patients with autoimmune hepatitis. PATIENTS AND METHODS: Retrospective analysis of pregnancies with autoimmune hepatitis followed in Centro Hospitalar do Porto, Portugal in the last ten years. RESULTS: We reported nine pregnancies in seven patients with autoimmune hepatitis. Two patients had documented liver cirrhosis prior to the pregnancy. In this study, 66.7% of patients were treated with azathioprine and 88.9% with prednisolone. Clinical improvements were observed in 11.1% of pregnancies and 22.2% exacerbations were diagnosed. There were six live births and two preterm deliveries (preterm delivery rate of 33%). We also report three first trimester miscarriages (early gestation miscarriage rate of 33%). There were no neonatal or maternal deaths. CONCLUSION: The favorable obstetric outcome is a realistic expectation in patients with autoimmune hepatitis. Tight monitoring and control of asymptomatic and unpredictable exacerbations, which are unrelated to the severity of the underlying disease, are essential to the prognosis of the current pregnancyinfo:eu-repo/semantics/publishedVersio

A new model for gravitational potential perturbations in disks of spiral galaxies. An application to our Galaxy

We propose a new, more realistic, description of the perturbed gravitational potential of spiral galaxies, with spiral arms having Gaussian-shaped groove profiles. We investigate the stable stellar orbits in galactic disks, using the new perturbed potential. The influence of the bulge mass on the stellar orbits in the inner regions of a disk is also investigated. The new description offers the advantage of easy control of the parameters of the Gaussian profile of its potential. We find a range of values for the perturbation amplitude from 400 to 800 km^2 s^{-2} kpc^{-1} which implies a maximum ratio of the tangential force to the axisymmetric force between 3% and 6%, approximately. Good self-consistency of arm shapes is obtained between the Inner Lindblad resonance (ILR) and the 4:1 resonance. Near the 4:1 resonance the response density starts to deviate from the imposed logarithmic spiral form. This creates bifurcations that appear as short arms. Therefore the deviation from a perfect logarithmic spiral in galaxies can be understood as a natural effect of the 4:1 resonance. Beyond the 4:1 resonance we find closed orbits which have similarities with the arms observed in our Galaxy. In regions near the center, in the presence of a massive bulge, elongated stellar orbits appear naturally, without imposing any bar-shaped potential, but only extending the spiral perturbation a little inward of the ILR. This suggests that a bar is formed with a half-size around 3 kpc by a mechanism similar to that of the spiral arms. The potential energy perturbation that we adopted represents an important step in the direction of self-consistency, compared to previous sine function descriptions of the potential. Our model produces a realistic description of the spiral structure, able to explain several details that were not yet understood.Comment: 12 pag., 11 fig. Accepted for publication in A&A, 2012 December 1

Korea and the BICs (Brazil, India and China) : catching up experiences

This paper tests a neo-Schumpeterian model with industry-level data to analyze how Brazil, India, and China are catching up with South Korea’s technological frontier in a globalized world. The paper validates Aghion et al.’s inverted-U hypothesis that industries that are closer to the technological frontier innovate to escape competition while longer distances discourage innovating. It suggests that for effective catching up, distance-shortening (or innovation-enhancing) policies may be a necessary complement to liberalization. South Korea and China combined a variety of distance-shortening policies with financial subsidies to promote high tech industries and an export-led growth strategy. Post-liberalization, they leveraged swift competition to spur catch-up. In comparison, Brazil, which was as rich as South Korea, and India, which was as rich as China in 1980, are catching up more slowly. Import-substitution industrialization strategies saddled Brazil and India with a large anti-export bias, and unfocused attention to innovation-enhancing policies dampened global competitiveness. Post liberalization, many of their industries were too far behind the technological frontier to effectively benefit from competition. The catch-up experiences of Brazil, India, and China with South Korea illustrate that distance from the technological frontier matters and that the design of country-specific distance- shortening policies can be an important complement to trade liberalization in promoting catching up with richer countries.Labor Policies,Economic Theory&Research,Water and Industry,E-Business,Knowledge for Development

Generalized baryon form factors and proton structure functions in the Sakai-Sugimoto model

We investigate the production of positive parity baryon resonances in proton electromagnetic scattering within the Sakai-Sugimoto model. The latter is a string model for the non-perturbative regime of large $N_c$ QCD. Using holographic techniques we calculate the generalized Dirac and Pauli form factors that describe resonance production. We use these results to estimate the contribution of resonance production to the proton structure functions. Interestingly, we find an approximate Callan-Gross relation for the structure functions in a regime of intermediate values of the Bjorken variable.Comment: v3: 38 pages, 25 figures. We added a new subsection in order to compare our results with experimental data. To appear in Nucl. Phys.

Towards Relativistic Skyrmions

We revisit baryons in the Skyrme model. Starting from static baryons in the helicity eigenstates, we generalize their wavefunctions to the non-static and relativistic regime. A new representation for gamma matrices in the soliton collective space is constructed and the corresponding Dirac equation is obtained. As an example, we draw consideration on how to apply this new representation on the calculus of vector current vacuum expectation values for baryon states of spin and isospin half and arbitrary momenta and we show how elastic form factors can be derived.Comment: 7 pages, 7th Conference Mathematical Methods in Physics - Londrina 2012, Rio de Janeiro, Brazi