462 research outputs found
Measuring random force noise for LISA aboard the LISA Pathfinder mission
The LTP (LISA Testflight Package), to be flown aboard the ESA / NASA LISA
Pathfinder mission, aims to demonstrate drag-free control for LISA test masses
with acceleration noise below 30 fm/s^2/Hz^1/2 from 1-30 mHz. This paper
describes the LTP measurement of random, position independent forces acting on
the test masses. In addition to putting an overall upper limit for all source
of random force noise, LTP will measure the conversion of several key
disturbances into acceleration noise and thus allow a more detailed
characterization of the drag-free performance to be expected for LISA.Comment: 7 pages, 3 figures. To be published in Classical and Quantum Gravity
with the proceedings of the 2003 Amaldi Meetin
Characterization of disturbance sources for LISA: torsion pendulum results
A torsion pendulum allows ground-based investigation of the purity of
free-fall for the LISA test masses inside their capacitive position sensor.
This paper presents recent improvements in our torsion pendulum facility that
have both increased the pendulum sensitivity and allowed detailed
characterization of several important sources of acceleration noise for the
LISA test masses. We discuss here an improved upper limit on random force noise
originating in the sensor. Additionally, we present new measurement techniques
and preliminary results for characterizing the forces caused by the sensor's
residual electrostatic fields, dielectric losses, residual spring-like
coupling, and temperature gradients.Comment: 11 pages, 8 figures, accepted for publication Classical and Quantum
Gravit
Measuring the LISA test mass magnetic proprieties with a torsion pendulum
Achieving the low frequency LISA sensitivity requires that the test masses
acting as the interferometer end mirrors are free-falling with an unprecedented
small degree of deviation. Magnetic disturbances, originating in the
interaction of the test mass with the environmental magnetic field, can
significantly deteriorate the LISA performance and can be parameterized through
the test mass remnant dipole moment and the magnetic susceptibility
. While the LISA test flight precursor LTP will investigate these effects
during the preliminary phases of the mission, the very stringent requirements
on the test mass magnetic cleanliness make ground-based characterization of its
magnetic proprieties paramount. We propose a torsion pendulum technique to
accurately measure on ground the magnetic proprieties of the LISA/LTP test
masses.Comment: 6 pages, 3 figure
Classificação, densidade e parâmetros nutricionais do milho.
Projeto/Plano de Ação: 11.11.11.111
Correlação entre resultados de densidade e classificação de milho realizado por duas empresas.
Projeto/Plano de Ação: 03.10.01.03
Upper limits on stray force noise for LISA
We have developed a torsion pendulum facility for LISA gravitational
reference sensor ground testing that allows us to put significant upper limits
on residual stray forces exerted by LISA-like position sensors on a
representative test mass and to characterize specific sources of disturbances
for LISA. We present here the details of the facility, the experimental
procedures used to maximize its sensitivity, and the techniques used to
characterize the pendulum itself that allowed us to reach a torque sensitivity
below 20 fNm /sqrt{Hz} from 0.3 to 10 mHz. We also discuss the implications of
the obtained results for LISA.Comment: To be published in Classical and Quantum Gravity, special issue on
Amaldi5 2003 conference proceedings (10 pages, 6 figures
Achieving geodetic motion for LISA test masses: ground testing result
The low-frequency resolution of space-based gravitational wave observatories
such as LISA (Laser Interferometry Space Antenna) hinges on the orbital purity
of a free-falling reference test mass inside a satellite shield. We present
here a torsion pendulum study of the forces that will disturb an orbiting test
mass inside a LISA capacitive position sensor. The pendulum, with a measured
torque noise floor below 10 fNm/sqrt{Hz} from 0.6 to 10 mHz, has allowed
placement of an upper limit on sensor force noise contributions, measurement of
the sensor electrostatic stiffness at the 5% level, and detection and
compensation of stray DC electrostatic biases at the mV level.Comment: 4 pages (revtex4) with 4 figure
On the Possibility of Measuring the Gravitomagnetic Clock Effect in an Earth Space-Based Experiment
In this paper the effect of the post-Newtonian gravitomagnetic force on the
mean longitudes of a pair of counter-rotating Earth artificial satellites
following almost identical circular equatorial orbits is investigated. The
possibility of measuring it is examined. The observable is the difference of
the times required to in passing from 0 to 2 for both senses of
motion. Such gravitomagnetic time shift, which is independent of the orbital
parameters of the satellites, amounts to 5 s for Earth; it is
cumulative and should be measured after a sufficiently high number of
revolutions. The major limiting factors are the unavoidable imperfect
cancellation of the Keplerian periods, which yields a constraint of 10
cm in knowing the difference between the semimajor axes of the satellites,
and the difference of the inclinations of the orbital planes which, for
, should be less than . A pair of spacecrafts
endowed with a sophisticated intersatellite tracking apparatus and drag-free
control down to 10 cm s Hz level might allow to meet
the stringent requirements posed by such a mission.Comment: LaTex2e, 22 pages, no tables, 1 figure, 38 references. Final version
accepted for publication in Classical and Quantum Gravit
Factors Predicting Early Failure of Etanercept in Rheumatoid Arthritis: An Analysis From the Gruppo Italiano di Studio sulla Early Arthritis (Italian Group for the Study of Early Arthritis) Registry
Objectives: This study aims to investigate the factors associated with early discontinuation (within one year) of etanercept (ETA) in rheumatoid arthritis (RA) patients who began ETA as first biologic disease-modifying antirheumatic drug (bDMARD) and who were entered into the Gruppo Italiano di Studio sulla Early Arthritis (Italian Group for the Study of Early Arthritis; GISEA) registry.Patients and methods: This registry-based cohort study included 477 RA patients (95 males, 382 females; median age 53 years; range 18 to 83 years) who began ETA as first bDMARD. Patient demographics, disease features and drugs were re-evaluated after 12 months. Baseline predictors of ETA discontinuation were estimated by univariate and multivariate analyses using Cox regression model.Results: Seventy patients (14.7%) discontinued ETA during the first year (for inefficacy in 55.8%, adverse events in 28.6%, and other reasons in 6.5%). Concurrent conventional synthetic DMARDs (csDMARDs) were reported in 54.3% of patients, mainly methotrexate (MTX), while 52.4% of subjects took low doses of glucocorticoids. Patients stopping ETA more frequently showed one or more comorbidities, mainly cardiovascular diseases (28.6% vs. 15.7% in patients stopping and continuing ETA, respectively, p=0.009). The presence of comorbidities and a combination therapy with csDMARDs other than MTX were independent factors associated with early discontinuation of ETA at multivariate Cox analysis.Conclusion: Although ETA demonstrated a high persistence in biologic-naive RA patients, about 15% of patients discontinued the treatment within 12 months. The presence of comorbidities and a combination therapy with csDMARDs other than MTX were the main factors for an early withdrawal of the drug
Probiotic yogurt with brazilian red propolis: physicochemical and bioactive properties, stability, and shelf life
This study aimed to evaluate the quality parameters in probiotic yogurt produced with Brazilian red propolis
to replace potassium sorbate used in conventional yogurt (CY). Microbiological stability and shelf life, physicochemical
properties (pH, acidity, chemical composition, and fatty acids), and bioactive properties (phenolic compounds and
antioxidant activity) were evaluated. The addition of red propolis (0.05%) to replace the potassium sorbate did not change
the pH, acidity, fatty acid profile, chemical composition, or shelf life. Microbiological stability of at least 28 days was
achieved, while a drastic reduction in the lactic acid bacteria content was observed in the CY during refrigeration storage.
Phenolic total contents were higher than those of the control, and consequently, yogurt with red propolis showed higher
antioxidant activity.We thank the Coordenação de Aperfeiçoamento de Pessoal de Nível
Superior (CAPES), Brazilian government, for scholarship support
(Finance Code 001), the Dr Cátia Ionara Santos Lucas (INSECTA
laboratory, UFRB, Cruz das Almas, Brazil), and the technical team
of the Polytechnic Institute of Bragança laboratory (Bragança,
Portugal) for their support during the research.info:eu-repo/semantics/publishedVersio
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