12,755 research outputs found
On central tendency and dispersion measures for intervals and hypercubes
The uncertainty or the variability of the data may be treated by considering,
rather than a single value for each data, the interval of values in which it
may fall. This paper studies the derivation of basic description statistics for
interval-valued datasets. We propose a geometrical approach in the
determination of summary statistics (central tendency and dispersion measures)
for interval-valued variables
Remark on lattice BRST invariance
A recently claimed resolution to the lattice Gribov problem in the context of
chiral lattice gauge theories is examined. Unfortunately, I find that the old
problem remains.Comment: 4 pages, plain TeX, presentation improved (see acknowledgments
Active role of elongation factor G in maintaining the mRNA reading frame during translation.
During translation, the ribosome moves along the mRNA one codon at a time with the help of elongation factor G (EF-G). Spontaneous changes in the translational reading frame are extremely rare, yet how the precise triplet-wise step is maintained is not clear. Here, we show that the ribosome is prone to spontaneous frameshifting on mRNA slippery sequences, whereas EF-G restricts frameshifting. EF-G helps to maintain the mRNA reading frame by guiding the A-site transfer RNA during translocation due to specific interactions with the tip of EF-G domain 4. Furthermore, EF-G accelerates ribosome rearrangements that restore the ribosome's control over the codon-anticodon interaction at the end of the movement. Our data explain how the mRNA reading frame is maintained during translation
SPIRE imaging of Mâ82: Cool dust in the wind and tidal streams
Mâ82 is a unique representative of a whole class of galaxies, starbursts with superwinds, in the Very Nearby Galaxy Survey with Herschel. In addition, its interaction with the Mâ81 group has stripped a significant portion of its interstellar medium from its disk. SPIRE maps now afford better characterization of the far-infrared emission from cool dust outside the disk, and sketch a far more complete picture of its mass distribution and energetics than previously possible. They show emission coincident in projection with the starburst wind and in a large halo, much more extended than the PAH band emission seen with Spitzer. Some complex substructures coincide with the brightest PAH filaments, and others with tidal streams seen in atomic hydrogen. We subtract the far-infrared emission of the starburst and underlying disk from the maps, and derive spatially-resolved far-infrared colors for the wind and halo. We interpret the results in terms of dust mass, dust temperature, and global physical conditions. In particular, we examine variations in the dust physical properties as a function of distance from the center and the wind polar axis, and conclude that more than two thirds of the extraplanar dust has been removed by tidal interaction, and not entrained by the starburst wind
The efficacy of halofantrine in the treatment of acute malaria in nonimmune travelers
A multicenter prospective trial was performed to investigate the efficacy and the tolerability of halofantrine in nonimmune patients with malaria imported from areas with drug-resistant falciparum parasites (mainly Africa). Forty-five of the 74 subjects were treated with a one-day regimen (3 x 500 mg) of halofantrine, and the other 29 received the same regimen with an additional treatment on day 7. In the second group, a 100% efficacy rate was demonstrated, but in the group receiving the one-day regimen, four recrudescences were observed in patients with falciparum malaria. Only five mild adverse reactions were seen, which disappeared spontaneously after the end of the treatment. We conclude that halofantrine is highly effective in curing malaria in nonimmune subjects. The treatment scheme for such persons should include an additional treatment on day 7 for nonimmune individuals. This drug was well tolerated in our patients, indicating that halofantrine will be useful in the treatment of multidrug-resistant malaria in nonimmune persons
The dust morphology of the elliptical Galaxy M86 with SPIRE
We present Herschel-SPIRE observations at 250â500âÎŒm of the giant elliptical galaxy Mâ86 and examine the distribution of the resolved cold dust emission and its relation with other galactic tracers. The SPIRE images reveal three dust components: emission from the central region; a dust lane extending north-south; and a bright emission feature 10âkpc to the south-east. We estimate that ~10^6âM_â of dust is spatially coincident with atomic and ionized hydrogen, originating from stripped material from the nearby spiral NGC 4438 due to recent tidal interactions with Mâ86. The gas-to-dust ratio of the cold gas component ranges from ~20â80. We discuss the different heating mechanisms for the dust features
The Phase Diagram and Spectrum of Gauge-Fixed Abelian Lattice Gauge Theory
We consider a lattice discretization of a covariantly gauge-fixed abelian
gauge theory. The gauge fixing is part of the action defining the theory, and
we study the phase diagram in detail. As there is no BRST symmetry on the
lattice, counterterms are needed, and we construct those explicitly. We show
that the proper adjustment of these counterterms drives the theory to a new
type of phase transition, at which we recover a continuum theory of (free)
photons. We present both numerical and (one-loop) perturbative results, and
show that they are in good agreement near this phase transition. Since
perturbation theory plays an important role, it is important to choose a
discretization of the gauge-fixing action such that lattice perturbation theory
is valid. Indeed, we find numerical evidence that lattice actions not
satisfying this requirement do not lead to the desired continuum limit. While
we do not consider fermions here, we argue that our results, in combination
with previous work, provide very strong evidence that this new phase transition
can be used to define abelian lattice chiral gauge theories.Comment: 42 pages, 30 figure
Instability tests for air-jet textured yarns
The air-jet texturing process is briefly introduced and its advantages over other texturing processes are summarized. Characteristics of air-jet textured yarns are stated with special reference to the stability of the yarns. Test methods used in industry and research to determine the "stability" or "instability" of air-jet textured yarns are critically reviewed. These methods involve different basic principles and therefore inevitably give different results. There is no consensus on a standard method. Effects of various test parameters, such as specimen length, test duration, and the alternatives of using a single yarn, a hank, or a skein as a test specimen are investigated. An improved test method is suggested as a standard instability test, and various existing methods are compared with it. Results of all the methods show similar trends for varying values of air pressure. Other yarn characteristics such as linear density, breaking elongation, and tenacity are also determined, and their indications of yarn quality are compared with the indications of instability tests. Stability test results alone provide misleading information regarding air-jet textured yarn quality
Thermal Kinetic Inductance Detectors for Millimeter-Wave Astrophysics
Thermal Kinetic Inductance Detectors (TKIDs) combine the excellent noise performance of traditional bolometers with a radio frequency (RF) multiplexing architecture that enables the large detector counts needed for the next generation of millimeter-wave instruments. Here we present dark prototype TKID pixels that demonstrate a noise equivalent power NEP = 2Ă10â»Âčâ·âW/Hz with a 1/f knee at 0.1 Hz, suitable for background-limited noise performance at 150 GHz from a ground-based site. We discuss the optimizations in the device design and fabrication techniques to realize optimal electrical performance and high quality factors at a bath temperature of 250 mK
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