Analytical calculation of pressure for confined atomic and molecular systems using the eXtreme-Pressure Polarizable Continuum Model

We show that the pressure acting on atoms and molecular systems within the compression cavity of the eXtreme-Pressure Polarizable Continuum method can be expressed in terms of the electron density of the systems and of the Pauli-repulsion confining potential. The analytical expression holds for spherical cavities as well as for cavities constructed from van der Waals spheres of the constituting atoms of the molecular systems

Assessment of leaf cover and crop soil cover in weed harrowing research using digital images

Objective assessment of crop soil cover, defined as the percentage of leaf cover that has been buried in soil due to weed harrowing, is crucial to further progress in post-emergence weed harrowing research. Up to now, crop soil cover has been assessed by visual scores, which are biased and context dependent. The aim of this study was to investigate whether digital image analysis is a feasible method to estimate crop soil cover in the early growth stages of cereals. Two main questions were examined: (1) how to capture suitable digital images under field conditions with a standard high-resolution digital camera and (2) how to analyse the images with an automated digital image analysis procedure. The importance of light conditions, camera angle, size of recorded area, growth stage and direction of harrowing were investigated in order to establish a standard for image capture and an automated image analysis procedure based on the excess green colour index was developed. The study shows that the automated digital image analysis procedure provided reliable estimations of leaf cover, defined as the as the proportion of pixels in digital images determined to be green, which were used to estimate crop soil cover. A standard for image capture is suggested and it is recommended to use digital image analysis to estimated crop soil cover in future research. The prospects of using digital image analysis in future weed harrowing research are discussed

In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver

Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the skatole concentration in plasma and fat. In the present study we investigated the effect of chicory on CYP mRNA and protein expression, as well as their activity. Male pigs were feed dried chicory root for 16 days before liver samples were collected. By the use of RT-PCR and Western blotting we showed that the mRNA and protein expression of CYP1A2 and 2A were increased in chicory fed pigs. The mRNA expression of CYP2E1 was increased, while there was no effect on protein expression. Activity of CYP1A2 and 2A were increased in chicory feed pigs; this was not the case for CYP2E1 activity. In conclusion; oral administration of chicory root for 16 days to pigs increased the mRNA expression of CYP1A2, 2A and 2E1; and the protein expression of CYP1A2 and 2A. The activities of CYP1A2 and 2A were increased

Band-steaming reduces laborious hand-weeding in vegetables

Band-steaming is a new method that may reduce the need for hand-weeding in demanding row crops like carrot and drilled onion. Band-steaming only affects a soil volume equal to the intra-row area of the subsequent crop, and effectively kills the weed seeds in this soil volume. Side-effects on beneficial soil organisms are minimized as compared to current steaming technology, but still need to be assessed

Discrimination in Mortgage Lending: Evidence from a Correspondence Experiment

We design and implement an experimental test for differential response by mortgage loan originators (MLOs) to requests for information about loans. Our e-mail correspondence experiment is designed to analyze differential treatment by client race and credit score. Our results show net discrimination by 1.8% of MLOs through non-response. We also find that MLOs offer more details about loans and are more likely to send follow up correspondence to whites. The effect of being African American on MLO response is equivalent to the effect of having a credit score that is 71 points lower

Caddo Ceramics on the Red River in North Central Texas

Caddo ceramics manufactured after A.D. 900 were widely traded in Texas, being found in some quantity on North Central, East Central, Central, and inland Southeast Texas archeological sites. They were also traded with prehistoric peoples in the Midwest (as far north as Iowa and Illinois) and the Southeastern U.S. While archeologists have known this for some time, much of the ceramic evidence for prehistoric Caddoan trade and exchange with other Native Americans has not been systematically compiled and studied, as became apparent during a recent review of the prehistoric and historic aboriginal pottery in Texas. Consequently, Caddoan archeologists are not yet in the position to confidently discuss the scope, timing, or direction of trade/exchange between Caddoan groups and surrounding non-Caddoan communities, or explore changes in the nature of social and economic relationships between particular Caddo groups and other prehistoric peoples. This paper represents part of our initial efforts to begin systematically compiling archeological information on the distribution and character of Caddo ceramic sherds and vessels outside what is considered the southern Caddoan archaeological area. In it, we report on Early and Late Caddo ceramics found by Dr. Ernest R. Martin at two sites along the Red River in North Central Texas, some 130 km or more west of the westernmost Caddo settlements on the Red River in Northeast Texas

Band steaming for intra-row weed control in direct-sown vegetables

Recent results with band-steaming in organic vegetables are presented

Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.)

Chicory (Cichorium intybus) has been shown to induce enzymes of pharmacokinetic relevance (cytochrome P450; CYP). The aim of this study was to investigate the effects of selected secondary plant metabolites with a global extract of chicory root, on the expression of hepatic CYP mRNA (1A2, 2A19, 2C33, 2D25, 2E1 and 3A29), using primary porcine hepatocytes. Of the tested secondary plant metabolites, artemisinin, scoparone, lactucin and esculetin all induced increased expression of specific CYPs, while esculin showed no effect. In contrast, a global extract of chicory root decreased the expression of CYP1A2, 2C33, 2D25 and 3A29 at high concentrations. The results suggest that purified secondary metabolites from chicory affect CYP expression and thereby might affect detoxification in general, and that global extracts of plants can have effects different from individual components