Asymmetric Synthesis of New Chiral Europium N,N'-Disuccinate Complexes:Shift Reagents for Aqueous Solutions and Application in the Enantiomeric Excess Determination of Amino Acids

The synthesis of new chiral N,N'-disuccinate ligands (R,R)-8, (R,R)-9, and (S,S)-10 from (5R)- or (SS)-(menthyloxy)-2(5H)-furanone is described. These ligands, after complexation with EuCl3.6H(2)O, are highly suitable as chiral shift reagents for the enantiomeric excess determination of amino acids and alpha-alkylated amino acids in aqueous solutions. Resolution experiments using various amino acids and their derivatives and a study of the pH dependency of the induced diastereomeric shift differences are included

A POLYNUCLEAR COPPER(I) COMPLEX WITH A SINGLE HELICAL STRUCTURE

The synthesis and crystal and molecular structure of a single helical polynuclear Cu(I) complex are described

Improved Synthesis of 2,6,6-trimethyl-1-cyclohexene-1-acetaldehyde, a Key Intermediate for Drimane-related Sesquiterpenes.

The titel compound is conveniently prepared in 65% overall yield by a two step synthesis starting from he commercially available β-ionone