Population Structure and Transmission Dynamics of Plasmodium vivax in the Republic of Korea Based on Microsatellite DNA Analysis

Vivax malaria is widely prevalent, mainly in Asia and South America with 390 million reported cases in 2009. Worldwide, in the same year, 2.85 billion people were at risk. Plasmodium vivax is prevalent not only in tropical and subtropical areas but also in temperate areas where there are no mosquitoes in cold seasons. While most malaria researchers are focusing their studies on the parasite in tropical areas, we examined the characteristics of P. vivax in South Korea (temperate area) temporally, using 10 highly polymorphic microsatellite DNA (a short tandem repeat DNA sequence) in the parasite genome, and highlighted the differences between the tropical and temperate populations. We found that the South Korean P. vivax population had low genetic diversity and low recombination rates in comparison to tropical P. vivax populations that had been reported. We also found that some of the parasite clones in the population were changing from 1994 to 2008, evidence suggesting the continual introduction of the parasite from other populations, probably from North Korea. Polymorphic DNA markers of the P. vivax parasite are useful tools for estimating the situation of its transmission in endemic areas

Psychoses et cancers :puzzle épidémiologique ou brouillage de l’abord clinique des psychopathologies en oncologie ?

This article is related to the evolution of a specific research, developed during the 20th century. This research is dedicated to assess “the cancer” incidence in the population of “the lunatics”, and more precisely in the “psychotic population”. It describes the paradigm of this research and the progressive definition of its questions. Moreover, it specifies the chosen diagnostic entities that are used in this research development. The highlights that treating the questions as an “epidemiological puzzle” is assuming and reflecting the acquisition of a medical model to think about mental disease. Because of this, in the field of oncology, psychopathology clinical approach has become outdated.SCOPUS: ar.jinfo:eu-repo/semantics/publishe