Teaching and learning color. An insight into STEM/STEAM approach

The paper aims to help define the STEM/STEAM approach to Color Education. Nowadays more and more schools embrace this approach as it seems to respond to a need for renewal of teaching while adapting it to the present time. However, this approach is not univocally defined, so that under this label fall experiences of color education of various kinds and different educational effectiveness. Therefore, this work intends to clarify the meaning of this approach. The article is divided into three parts that show the methodological path undertaken. In the first part, some invariant properties of situations classified as STEM/STEAM were identified; in the second part, the invariants were described in terms of didactic variables inferred from the literature and some STEM/STEAM teaching activities; in the third part, some procedural principles to guide teachers' work were formulated and discussed in the context of teaching and learning about color

La présence française au Chili durant le XIXe siècle : le cas de Raymond Auguste Quinsac Monvoisin (1790-1870)

Québec Université Laval, Bibliothèque 201

Prospective Teachers’ Representations on the Concept of Force

none4noWe present a study on teacher education and, in particular, on Physics. Our assumption is that General Didactics and Disciplinary Didactic constitute two fundamental components of teachers’ professional development and therefore both must be used to interpret didactic phenomena adequately. This research involves a sample of 274 prospective teachers, enrolled in the Primary Education Sciences degrees in three Italian Universities (Milano Bicocca, Udine, Urbino,). It concerns the study of the spontaneous representations produced by students to foster understanding of the force concept and on the reasons given to motivate their effectiveness on an educational level and disciplinary one. The research tools and methods were developed by crossing the literature of General Didactics and Physics Education, identifying analytical categories that emerge from two different and complementary perspectives. In the broad spectrum of students’ conceptions, given by this double perspective, some aspects stand out: most of the representations do not include the representation of the forces at play, but rather imply a precise didactic approach inherent to the concept of force. This is confirmed by the analysis of the didactic and disciplinary motivations, in which a frequent identification of the two types of motivations emerges.openBerta Martini, Marisa Michelini, Alberto Stefanel, Monica TombolatoMartini, Berta; Michelini, Marisa; Stefanel, Alberto; Tombolato, Monic

Chapter The Influence of Candida spp. in Intestinal Microbiota; Diet Therapy, the Emerging Conditions Related to Candida in Athletes and Elderly People

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The Influence of <em>Candida</em> spp. in Intestinal Microbiota; Diet Therapy, the Emerging Conditions Related to <em>Candida</em> in Athletes and Elderly People

The presence of Candida in the gut is normal, but an overproduction may lead to serious health problems due to an imbalanced gut, causing gut-related symptoms such as bowel movement changes, excessive gas, etc. Some diseases, such as Crohn’s disease and ulcerative colitis, are associated with an overgrowth of Candida in the gastrointestinal tract. Several recent studies have shown that a prolonged candidiasis within the intestines is associated with Candida overgrowth syndrome or chronic fatigue syndrome. A healthy digestive system relies on a good balance of bacteria that live in the gut, and an important role in maintaining this balance is having the ingested type of food. Candida overgrowth can be prevented first of all by healthy eating patterns, as susceptibility is increased by a high-sugar diet and diabetes or nutritional deficiencies causing a dysregulated immune system. In general, Candida-associated conditions have a high impact on performance. Recent research has shown an increasing interest in the Candida-related conditions and diseases

Combining doxorubicin-nanobubbles and shockwaves for Anaplastic thyroid cancer treatment: Preclinical study in a xenograft mouse model

Anaplastic thyroid cancer is one of the most lethal diseases, and a curative therapy does not exist. Doxorubicin, the only drug approved for anaplastic thyroid cancer treatment, has a very low response rate and causes numerous side effects among which cardiotoxicity is the most prominent. Thus, doxorubicin delivery to the tumor site could be an import goal aimed to improve the drug efficacy and to reduce its systemic side effects. We recently reported that, in human anaplastic thyroid cancer cell lines, combining doxorubicin-loaded nanobubbles with extracorporeal shock waves, acoustic waves used in lithotripsy and orthopedics without side effects, increased the intracellular drug content and in vitro cytotoxicity. In the present study, we tested the efficacy of this treatment on a human anaplastic thyroid cancer xenograft mouse model. After 21 days, the combined treatment determined the greatest drug accumulation in tumors with consequent reduction of tumor volume and weight, and an extension of the tumor doubling time. Mechanistically, the treatment induced tumor apoptosis and decreased cell proliferation. Finally, although doxorubicin caused the increase of fibrosis markers and oxidative stress in animal hearts, loading doxorubicin into nanobubbles avoided these effects preventing heart damage. The improvement of doxorubicin anti-tumor effects together with the prevention of heart damage suggests that the combination of doxorubicin-loaded nanobubbles with extracorporeal shock waves might be a promising drug delivery system for anaplastic thyroid cancer treatment.</jats:p