SLC1 family of amino acid transporters (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

The SLC1 family of sodium dependent transporters includes the plasma membrane located glutamate transporters and the neutral amino acid transporters ASCT1 and ASCT2 [1, 49, 36, 37, 7]

SLC1 family of amino acid transporters in GtoPdb v.2023.1

The SLC1 family of sodium dependent transporters includes the plasma membrane located glutamate transporters and the neutral amino acid transporters ASCT1 and ASCT2 [3, 52, 39, 40, 9]

SLC1 family of amino acid transporters (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

The SLC1 family of sodium dependent transporters includes the plasma membrane located glutamate transporters and the neutral amino acid transporters ASCT1 and ASCT2 [1, 49, 36, 37, 7]

Hepatic trisegmentectomy and other liver resections

Trisegmentectomy, extended right hepatic lobectomy, is the removal of the true right lobe of the liver in continuity with most or all of the medial segment of the left lobe. Some important features of the operation have not been well described previously. To perform trisegmentectomy, safely, a fusion of liver tissue covering the umbilical fissure at the level of the falciform ligament must first be split open in many patients. The left branches of the portal triad structures are mobilized from the undersurface of the liver nearly to but not into the umbilical fissure. The blood supply and duct drainage of the medial segment originate within the umbilical fissure and feed back toward the right side buried in liver substance. They are found with blunt dissection just to the right of the flaciform ligament, encircled and ligated. Failure to appreciate this switch back anatomic arrangement may lead to injury of the blood supply or biliary drainage of the residual lateral segment. Parenthetically, the mirror image operation of lateral segmentectomy could result in devascularization of the medial segment if dissection and ligation were performed within the umbilical fissure instead of well to the left of this landmark. In most trisegmentectomies, the left portion of the caudate lobe is not removed. This small piece of tissue is interposed between the lateral segment and the inferior vena cava into which it drains by small tributaries. If the left portion of the caudate lobe is to be excised, it is necessary to ligate the last two posteriorly running branches before the main left trunks of the portal triad structures reach the umbilical fissure. Once this step is taken and if the caudate removal is completed, the remaining lateral segment usually has only one remaining outflow, that of the left hepatic vein. The other principles of trisegmentectomy are the same as with less radical subtotal hepatic resection. These include vascular suture closure of the main outflow veins, avoidance of parasegmental planes that leave behind a strip of devitalized tissue, preservation of intersegmental or interlobar veins, omission of techniques that sew shut or otherwise cover the raw surface of the remnant and provision of adequate drainage of dead space. After trisegmentectomy and also after true lobectomy, this last objective is usually met by leaving part of the operative incision open. Using thse guidelines, there has been no mortality with 27 hepatic resections carried out since 1963, including 14 trisegmentectomies

Hepatic transplantation, 1975.

This report reviews experience with 97 patients given liver transplants. We regard out survival statistics as unsatisfactory, but fell they should encourage further work since 22 patients have survived at least one year with a maximum survival of 5 13 YEARS. The Achilles' heel of liver transplantation os bile duct reconstruction. We presently rely upon Roux-en-Y reconstruction, or alternatively, duct-to-duct anastomosis with a T-tube stent. The prime indication for liver replacement is non-neoplastic liver disease, but a favourable malignancy for treatment may prove to be small intrahepatic duct cell carcinomas

Influence of yoga on learners with attention deficit hyperactive disorder

The aim of this study was to explore the influence of yoga on learners with ADHD. In order to reach the aim of this study, an initial literature study was executed to describe ADHD and the practice of yoga. Particular aspects such as concentration, anxiety, self-esteem and aggression were highlighted. Semi-structured interviews with parents, teachers, learners and one yoga instructor were used to conduct the empirical study. Valuable data was also collected from the learners using projection tests and self-esteem questionnaires. Assessments were conducted at two points: during the situation analysis and at the outcome of the yoga intervention. Based on the data collected and analysed, findings were made and conclusions were drawn regarding the influence of yoga on learners with ADHD focusing on the aspects of concentration, anxiety, self-esteem and aggression. Recommendations for future research were then proposed.Psychology of EducationM. Ed. (Guidance and Counselling

Ex vivo renal perfusion and autotransplantation in treatment of calculous disease or abdominal aortic aneurysm.

Two more indications are described for temporary ex vivo perfusion of kidneys with revascularization of these organs as autografts to orthotopic or heterotopic locations. One of the patients had staghorn calculi which were removed from a solitary kidney. The other patient had both kidneys autografted in the course of a surgical procedure on an extensive abdominal aortic aneurysm