8 research outputs found
The Tarpaulin and the Tablecloth: Cover and Non-Traditional Education in Traditional Spaces of Schooling
- Author
- A Appadurai
- AA Arrellanes
- BE Loyo
- C Beas Torres
- CNTE
- ComisiĂłn Civil Internacional de ObservacisĂłn por los Derechos Humanos
- D Denham
- DE Osorno
- E Bautista MartĂnez
- F Verástegui
- G Esteva
- G Zafra
- HA Giroux
- I Yescas MartĂnez
- J Pickerill
- J Sotelo Marbán
- JP Gee
- K Norget
- K Simonsen
- M Dean
- M Giugale
- P Freire
- P Lipman
- R Trinidad Galván
- S Holloway
- SEDES 22
- SEP/SNTE
- VR MartĂnez Vásquez
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Degradation of poly aromatic fractions of crude oil and detection of catabolic genes in hydrocarbon-degrading bacteria isolated from Agbabu bitumen sediments in Ondo State
- Author
- Amini S Zulkify AH, et al.
- Baek KH Yoon BD, Oh HM, et al.
- Boonchan S Britz ML, Stanley GA
- Das K Mukherjee F
- Etoumi A Musrati IE, Gammoudi BE, et al.
- Gupta G Kumar V, Pal AK
- Islas-garcia A Vega-loyo L, Aguilar-lopez R, et al.
- Ji H Gong Y, Duan J, et al.
- Mao J Luo Y, Teng Y, et al.
- Margesin R Schinner F
- Mwaura AN Mbatia BN, Muge EK, et al.
- Olabemiwo MO Adediran GO, Adekola FA, et al.
- Olabemiwo OM Adediran GO, Adekola FA, et al.
- Semple KT Morriss A, Paton GI
- Watanabe K
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2019
- Field of study
Enhanced Expression of CD69 and CD25 Antigen on Human Peripheral Blood Mononuclear Cells by Prolactin
- Author
- Afeltra A Galeazzi M, Ferri GM, Amoroso A, De Pita O, Porzio F,
- Crispin JC Martinez A, de Pablo P, Velasquillo C, Alcocer-Varela J
- Dube D Kelley PA, Pelletier G
- El-Garf A Salah S, Shaarawy M, Zaki S, Anwer S
- Folomeev M Prokaeva T, Nassonova V
- Fujio TAKEUCHI
- Halko G Urrows S, Affleks G, Waterman J
- Jara L Graef A, Lavalle C
- Kazuhiko YAMAMOTO
- Kenji TAKIZAWA
- Lavalle C Loyo E, Paniagua R
- Mukherjee P Mastro AM, Hymer WC
- Nagafuchi H Suzuki N, Kaneko A, Asai T, Sakane T
- Neidhart M
- Pacilio M Migliaresi S, Meli R, Ambrosone L, Bigliardo B, Di Carlo R
- Rosen JM Matusik RJ, Richards DA, Gupta P, Rodgers JR
- Rovensky J Jurankova E, Rauova L, Blazickova S, Lukac J, Veselkova Z,
- Russell DH Kibler R, Matrisian L, Larson DF, Poulos B, Magun BE
- Seiichi KITANI
- Shiu RP Elsholtz HP, Tanaka T, Friesen HG, Gout PW, Beer CT, et al.
- Skwarlo-Sonta K
- Su CC Shau WY, Wang CR, Chuang CY, Chen CY
- Publication venue
- 'Japan Endocrine Society'
- Publication date
- 01/01/2005
- Field of study
An international SUrvey on non-iNvaSive tecHniques to assess the mIcrocirculation in patients with RayNaud'€™s phEnomenon (SUNSHINE survey)
- Author
- A. Abdessemed
- A. Balbir-Gurman
- A. Baranauskaite
- A. Hij
- A. Makol
- A. Nitsche
- A. Orenti
- A. Sulli
- A. Sulli
- A. Vacca
- A. Valenzuela
- A. Vargas
- A.L. Herrick
- B. Derfalvi
- B. Serrano Benavente
- B. Sozeri
- B. Stamenkovic
- B.E. Bica
- C. Abud Mendoza
- C. Ancuta
- C. Bertolazzi
- C. Chizzolini
- C. De La Puente
- C. Ickinger
- C. Kayser
- C. Mihai
- C. Pain
- C. Sunderkotter
- C. Von Muhlen
- D. Khanna
- D. Krasowska
- D. Launay
- D. Veale
- D.B. De Araujo
- D.M. Kaliterna
- E. Á
- E. De Langhe
- E. Hachulla
- E. Loyo
- E. Naredo
- E. Rosato
- F. Boin
- F. Ingegnoli
- F. Sztajnbok
- F. Van Den Hoogen
- F.J. Longo
- F.M.F. Moraes
- G. Dinsdale
- G. Hernandez Molina
- G. Moroncini
- G. Riemekasten
- G. Szucs
- H. Dobrev
- H. Fragoso Loyo
- I. Foeldvari
- I. Janta
- J. Akikusa
- J. Cracowski
- J. Pauling
- J. Sotoca Ferná
- K. Khan Ajaz
- K. Romanowska-Pró
- K. Rouster Stevens
- K. Solanki
- K. Wierzba
- L. Ananyeva
- L. Belloli
- L. Beretta
- L. Lewandowski
- L. Santos
- L.A. Saketkoo
- M. Bareš
- M. Becker
- M. Curran
- M. Cutolo
- M. Gutierrez
- M. Hufnagel
- M. Hughes
- M. Inanç
- M. Michalska Jakubus
- M. Milchert
- M. Petraitis
- M. Puszczewicz
- M.J. Audisio
- M.J. Molina
- M.N. Mamani
- M.T. Terreri
- N. Aktay Ayaz
- N. Fathi
- N. Juan Carlos
- N. Ughi
- O. Distler
- O. Sander
- P. Boracchi
- P. Caramaschi
- P. Garcí
- P. Hasler
- P. Ostojic
- P.N. Ö
- R. Beč
- R. Cimaz
- R. De Angelis
- R. Dobrota
- R. Hesselstrand
- R. Irace
- R. Lima
- R. Petty
- R.S.T. Rodrí
- S. Benseler
- S. Guiducci
- S. Kubo
- S. Lambova
- S. Payne-poff
- S. Popa
- S. Rednic
- S. Stebbings
- S. Yavuz
- T. Daikeler
- T. Frech
- T. Minier
- T. Schmeiser
- T. Shevtsova
- U. Mü
- U. Walker
- V. Riccieri
- V. Smith
- V. Vilela
- W. Hermann
- Y. Allanore
- Y. Braun-moscovici
- Y. Uziel
- Z. Thierry
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
To canvas opinion concerning the role of non-invasive techniques in the assessment of patients with Raynaud's phenomenon (Rp) in clinical and research settings: four nailfold capillaroscopy methods [videocapillaroscopy (NVC), dermoscopy, stereomicroscopy, digital USB microscopy], four laser Doppler methods (laser Doppler flowmetry, imaging, anemometry/velocimetry, laser speckle contrast analysis), thermographic imaging, and upper limb arterial Doppler ultrasound. Emails with a link to the survey were sent to physicians from the European Scleroderma Trials and Research group (EUSTAR), the EULAR Study Group on Microcirculation in Rheumatic Diseases (SG_MC/RD) and members of the pediatric rheumatology Email board. The main descriptive analysis related to physicians looking after adult patients, with some analysis also of opinions from paediatric rheumatologists. 106 'adult physicians' responded (a response rate of 25.8%), of whom 68.9% were European, and 81.1% practising for more than 10 years. Nineteen paediatricians responded. The most widely available technique was NVC (72.7%). Nailfold capillaroscopy was most frequently performed by the physician him/herself, using different types of equipment relating to availability. Most rheumatologists reported high levels of appropriateness for NVC in both clinical and research settings for global assessment and differential diagnosis of Rp. Other techniques were less used. Of all the different techniques, nailfold capillaroscopy was the one most used in both clinical and research settings by adult physicians, the majority of whom use NVC in their everyday practice. The low proportion of clinicians using other techniques suggests that these are currently mainly research tools, available only in specialist centres
Surgical Management of the Internal Nasal Valve: A Review of Surgical Approaches
- Author
- AF Haas
- AR Sedaghat
- B Millman
- BE Howard
- C Chen
- C Cingi
- C Murakami
- C Nigro
- CG Hurbis
- D Awengen
- D Wexler
- DH Stacey
- DJ Bottini
- DJ Genther
- DJ Menger
- DM Barrett
- DM Poetker
- DS Lee
- DW Hsu
- DY Chua
- EM Weaver
- F Aksoy
- F Konig
- G Amodeo
- G Matteo
- G Sulsenti
- GS Hamilton
- H Byrd
- I Rasic
- JA Moche
- JC Bewick
- JD Bloom
- JF Teichgraeber
- JH Sheen
- JK Goudakos
- JP Naughton
- JR White Jr
- JS Haight
- JS Rhee
- L Kim
- M Friedman
- M Friedman
- M Gelardi
- M Loyo
- M Mamanov
- M Samaha
- M Wittkopf
- MA Abdelwahab
- MBM Constantian
- MG Stewart
- MS Mendelsohn
- N Rao
- ND Goldman
- O Friedman
- P Cole
- PJ Mink
- RC Paniello
- RP Gruber
- S Park
- S Samra
- SE Hassanpour
- SJAC Van den Broek
- SP Moubayed
- SR Chaiet
- V Cervelli
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Operational Architectonics Methodology for EEG Analysis: Theory and Results
- Author
- A Arieli
- A Burgess
- A Chella
- A Collins
- A Dietrich
- A Hadjipapas
- A Karni
- A Pascual-Leone
- A Revonsuo
- A Rotarska-Jagiela
- A Trehub
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AA Fingelkurts
- AB Kirillov
- AK Engel
- AK Seth
- AL Barabasi
- AR Damasio
- AR McIntosh
- AY Kaplan
- AY Kaplan
- AY Kaplan
- AY Kaplan
- AY Kaplan
- AY Kaplan
- AY Kaplan
- AY Kaplan
- B Dresp-Langley
- B Hellwig
- B Horwitz
- B Shen
- BB Averbeck
- BE Brodsky
- BE Brodsky
- BH Jansen
- BJ Moore
- BJ West
- BS Oken
- C Adami
- C Kirchenheim Von
- C Koch
- C Leeuwen van
- C Malsburg von der
- C Stam
- C Vincent
- CE Beijsterveldt van
- CEM Beijsterveldt van
- CEM Beijsterveldt van
- CFV Latchoumane
- CJ Chu
- CJ Stam
- CJ Stam
- CL Ehlers
- CW Sem-Jacobsen
- D Chalmers
- D Lehmann
- D Lehmann
- D Lehmann
- D Lehmann
- D Lehmann
- D Lehmann
- D Mantini
- D Meunier
- D Plenz
- D Plenz
- D Ville Van de
- DA Gusnard
- DA Gusnard
- DA Putilov
- DB Chorlian
- DJ Watts
- DJA Smit
- DO Hebb
- DS Bassett
- DS Bassett
- DS Bassett
- E BaĹźar
- E BaĹźar
- E BaĹźar
- E BaĹźar
- E BaĹźar
- E BaĹźar
- E Leznik
- E Mignot
- E Pöppel
- E Verevkin
- EJ Speckmann
- EM Izhikevich
- ER John
- F Freyer
- F Lopes da Silva
- F Miwakeichi
- F Varela
- FH Lopes da Silva
- G Bodenstein
- G Buzsáki
- G Buzsáki
- G Buzsáki
- G Indiveri
- G Lantz
- G Northoff
- G Palm
- G Thut
- G Tononi
- G Tononi
- GC Baal van
- GG Knyazev
- GJ Siegle
- GM Edelman
- GN Boldyreva
- GV Wallenstein
- H Berger
- H Eichenbaum
- H Haken
- H Hori
- H Kunkel
- H Ozaki
- H Tost
- H Zeplin
- HA Simon
- HA Simon
- HE Stanley
- HH Stassen
- HH Stassen
- HJ Eysenck
- HU Wittchen
- I Aleksander
- IHA Franken
- IV Burov
- J Fell
- J Johnstone
- J Kounios
- J McCarthy
- J McFadden
- J Pardey
- J Pascual-Leone
- J Ramos-Loyo
- J Triesch
- JA Fodor
- JAS Kelso
- JAS Kelso
- JAS Kelso
- JAS Kelso
- JE LeDoux
- JE Skinner
- JH Gruzelier
- JM Beggs
- JM Fuster
- JM Palva
- JM Siegel
- JR Hughes
- JS Barlow
- K Friston
- K-H Bäuml
- KA Dawson
- KA Kooi
- KJ Friston
- KJ Friston
- KW Fischer
- L Angel
- L Glass
- L Miller
- L Silvestri
- M Ainsworth
- M Breakspear
- M Breakspear
- M Corsi-Cabrera
- M Deistler
- M Hämäläinen
- M Kaiser
- M Kaiser
- M Kuperstein
- M Minsky
- M Minsky
- M Molle
- M MĂĽller-Linow
- M Rubinov
- M Shanahan
- M Tsodyks
- MC Salinsky
- ME Raichle
- ME Raichle
- MF Mason
- MH Lee
- MM Mesulam
- MN Livanov
- MN Livanov
- MV Bodunov
- MX Cohen
- ND Volkow
- NE Sviderskaya
- NP Bekhtereva
- O David
- O Holland
- O Holland
- O Sporns
- O Sporns
- P Allegrini
- P Allegrini
- P Allegrini
- P Andras
- P Bak
- P Fossati
- P Fries
- P Geert van
- P Herscovitch
- P Joensen
- P Landa
- P Naish
- PA Robinson
- PE Davis
- PJ Uhlhaas
- PL Nunez
- PL Nunez
- PL Nunez
- PS Churchland
- PY Collins
- R Brown
- R Case
- R Case
- R Elul
- R Elul
- R Elul
- R Elul
- R Ingram
- R Kozma
- R Kozma
- R Manuca
- R Stickgold
- RF Betzel
- RJ Davidson
- RJ Ilmoniemi
- RJ Moran
- RK Orkand
- RK Pan
- RL Buckner
- RW Thatcher
- RW Thatcher
- RW Thatcher
- RW Thatcher
- S Boccaletti
- S Diamond
- S Fujisawa
- S Geisser
- S Kallio
- S Micheloyannis
- S Micheloyannis
- S Monto
- S Palva
- S Palva
- S Pockett
- S Zeki
- S Zeki
- SA Weiss
- SI Soroko
- SJ Albada van
- SL Bressler
- SL Bressler
- SL Bressler
- SL Bressler
- SL Bressler
- SL Shishkin
- SV Borisov
- SV Borisov
- SW Kuffler
- SW Kuffler
- T Gasser
- T Harmony
- T Kinoshita
- T Metzinger
- T Metzinger
- TE Feinberg
- TE Feinberg
- TE Feinberg
- TE Robinson
- TG Buchman
- TH Bullock
- TH Bullock
- TH Bullock
- TH Bullock
- TJ Muller
- TJ Ornstein
- TJ Vries De
- TR Insel
- TR Lund
- V Braitenberg
- V Noreika
- VA Vakorin
- VE Pollock
- VL Towle
- VS Rotenberg
- VS Rusinov
- VV Lazarev
- VV Lazarev
- W Freeman
- W Freeman
- W Gersch
- W Klimesch
- W Klimesch
- W Klimesch
- W Klimesch
- W Klimesch
- W Klimesch
- W Klonowski
- W Köhler
- W Singer
- W Singer
- WA Truccolo
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WJ Freeman
- WK Strik
- WL Shew
- WM Herrmann
- WS Tirsch
- Y Ben-Ari
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Ezetimibe added to statin therapy after acute coronary syndromes
- Author
- Aagnes I
- Aambakk MB
- Aase O
- Aaser E
- Abdel-Latief A
- Abell T
- Aboufakher R
- Abramson B
- Abrantes J
- Achilli A
- Adams A
- Adams K
- Adamus J
- Addington J
- Adgey A
- Adjei A
- Agarwal J
- Aggarwal A
- Aggarwal K
- Aggarwal R
- Agocha A
- Agraou B
- Aguirre O
- Ahmed A
- Ahmed O
- Ahsan A
- Airaksinen J
- Airoldi F
- Aji J
- Akkad H
- Akubzanova E
- Al-Ani R
- Al-Jumaily J
- Alameda J
- Albirini A
- Albuquerque A
- Albuquerque D
- Alcasena S
- Alexander J
- Alfonso F
- Ali MI
- Alings MA
- Allall O
- Allen J
- Allen RP
- Allred S
- Almeira AS
- Alonso L
- Alsagheer S
- Alshaher M
- Altschuller A
- Alvarez J
- Alvarez J
- Alvarez Y
- Alves A
- Amidon T
- Amos M
- Anaszewicz M
- Andersen M
- Andersen O
- Andersson E
- Andersson G
- Andrade G
- Andrade M
- Andrea B
- Andreou C
- Antonangelo A
- Antorrena I
- Appel K
- Arana C
- Aranda M
- Araujo J
- Arce R
- Ardito RV
- Ardito W
- Arend C
- Arias V
- Armada E
- Armstrong P
- Arnold A
- Arnold M
- Arntsen BI
- Arora P
- Aros F
- Arriagada G
- Arriagada G
- Artaecheverria J
- Arvesen K
- Arvigo L
- Ash Y
- Aske R
- Ata N
- Atar D
- Atar S
- Atassi K
- Atieh M
- Atkinson C
- Atzenhofer-Baumgartner K
- Auer J
- Aug L
- Ausen K
- Aycock G
- Aylward P
- Aylward P
- Ayres T
- Azize G
- Azrin M
- Azzolini P
- Babu R
- Bach R
- Badings EA
- Baeza N
- Baig M
- Baiz A
- Bajcsi É
- Balaguera J
- Balcells E
- Baldari D
- Baldus S
- Bali H
- Ballantyne C
- Ballmer P
- Banerjee S
- Bang-Hansen T
- Banikova A
- Bankowski D
- Banks K
- Bansal M
- Baraona F
- Barber C
- Barber C
- Barbir M
- Barillas O
- Barnes D
- Barnett O
- Barr C
- Barrett J
- Barringhaus K
- Barron M
- Bartels GL
- Basilio E
- Bass M
- Bassand J
- Bassand JP
- Bassand JP
- Basso V
- Bata I
- Battikadi S
- Battin D
- Bauer B
- Baumanns S
- Bautista J
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- Bayer M
- Bayles A
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- Beaudry M
- Bedoya R
- Been M
- Belicova M
- Bell K
- Belle L
- Beloscar J
- Beltran R
- Beltrano MC
- Ben-Aharon J
- Ben-Yehuda O
- Benetar J
- Bengtsson PO
- Bennermo M
- Bennett J
- Benyahya L
- Beresford P
- Berezniakov I
- Berger M
- Berger-Kucza A
- Bergeron J
- Berglund M
- Berglund R
- Bergsten J
- Berk M
- Berli M
- Bernardi D
- Berra F
- Berrospi P
- Bertolet B
- Bescos L
- Bethea C
- Bethencourt A
- Betti I
- Betzu R
- Bhalla H
- Bhalodkar N
- Bhargava M
- Bhargava R
- Bhargavi M
- Bhesania T
- Biasucci L
- Biedermann B
- Bikkina M
- Bilazarian S
- Bilodeau N
- Bin Ismail O
- Binaghi G
- Birkemeyer R
- Birnbaum Y
- Bishop A
- Bishop B
- Bishop C
- Bissett J
- Bissett J
- Bittel B
- Bitzer V
- Bjornstad H
- Blacher MG
- Blais D
- Blank E
- Blazing M
- Blazing M
- Blazing M
- Blazing Michael A.
- Blessing E
- Block D
- Bluguermann J
- Blumberg E
- Bobek M
- Bocconcelli P
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- Bodanese L
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- Boehm S
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- Bohorquez R
- Bohula Erin A.
- Boliek W
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- Bone C
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- Book K
- Boomer L
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- Botero R
- Bottzauw J
- Botwin S
- Boudriot E
- Bouvier JM
- Bowden W
- Bozek B
- Bradford L
- Bradford L
- Brady A
- Brady A
- Brady A
- Braga J
- Branca G
- Branny M
- Branzi A
- Braun P
- Braunwald Eugene
- Breen J
- Brike C
- Britto F
- Britto F
- Britto F
- Broadwater S
- Bronnum-Schou J
- Brossoit R
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- Brown J
- Brunelli C
- Brunelli C
- Brunk S
- Bruno N
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- Brussee H
- Bryniarski L
- Budzon S
- Bueno M
- Buerke M
- Buerke M
- Bugos V
- Buijs EM
- Buijs F
- Bullivant M
- Burgess L
- Burghard S
- Burley T
- Burton J
- Buss I
- Bustamante G
- Butcher R
- Butkus E
- Butter C
- Buzetti C
- Byfuglien A
- Cabrera-Santamaria A
- CalderĂłn MJ
- Calic S
- Califf
- Calpar I
- Calzolari D
- Campbell C
- Campbell T
- Campos C
- Cannon C
- Cannon C
- Cannon Christopher P.
- Canto J
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- Capucci A
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- Cardillo MT
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- Carell E
- Carell E
- Carey C
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- Carlevaro O
- Carling-Chambers L
- Carlsson F
- Carmelo M
- Carr K
- Carrageta M
- Carrageta M
- Carrageta M
- Carrié D
- Carswell BS
- Cartasegna L
- Caruso O
- Casalins M
- Casares G
- Caso P
- Caspi A
- Cassadonte F
- Cassavar D
- Cassel G
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- Centeno E
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- Cepeda M
- Cequier A
- Chadwyn D
- Chae SC
- Chalavarya G
- Chambers J
- Chandler G
- Chandna H
- Chandna H
- Chandna H
- Chandra P
- Chandraratna P
- Chandrasekaran S
- Chang D
- Chang G
- Chang K
- Chang K
- Chang M
- Charng M
- Chattree K
- Chavarri M
- Chavez V
- Chee K
- Chernick R
- Chessa P
- Cheung S
- Chew D
- Chhabra A
- Chian-Yi W
- Chiariello M
- Chilakamarri V
- Childs A
- Childs C
- Chiodi L
- Chiu A
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- Zanolin D
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- Zweiker R
- Ă…ngman K
- Édes I
- Ă–stberg S
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2015
- Field of study
BACKGROUND: Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal cholesterol absorption, can reduce the rate of cardiovascular events further is not known. METHODS: We conducted a double-blind, randomized trial involving 18,144 patients who had been hospitalized for an acute coronary syndrome within the preceding 10 days and had LDL cholesterol levels of 50 to 100 mg per deciliter (1.3 to 2.6 mmol per liter) if they were receiving lipid-lowering therapy or 50 to 125 mg per deciliter (1.3 to 3.2 mmol per liter) if they were not receiving lipid-lowering therapy. The combination of simvastatin (40 mg) and ezetimibe (10 mg) (simvastatin-ezetimibe) was compared with simvastatin (40 mg) and placebo (simvastatin monotherapy). The primary end point was a composite of cardiovascular death, nonfatal myocardial infarction, unstable angina requiring rehospitalization, coronary revascularization ( 6530 days after randomization), or nonfatal stroke. The median follow-up was 6 years. RESULTS: The median time-weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin-ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin-monotherapy group (P<0.001). The Kaplan-Meier event rate for the primary end point at 7 years was 32.7% in the simvastatin-ezetimibe group, as compared with 34.7% in the simvastatin-monotherapy group (absolute risk difference, 2.0 percentage points; hazard ratio, 0.936; 95% confidence interval, 0.89 to 0.99; P = 0.016). Rates of pre-specified muscle, gallbladder, and hepatic adverse effects and cancer were similar in the two groups. CONCLUSIONS: When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit