28 research outputs found
Oxidative Stress Is Increased in Combined Oral Contraceptives Users and Is Positively Associated with High-Sensitivity C-Reactive Protein
Information concerning the mechanisms underlying oxidative stress and low-grade inflammation in young healthy women predisposing eventually to future diseases is scarce. We investigated the relationship of oxidative stress and high-sensitivity C-reactive protein (hsCRP) in fertile-age women by oral combined contraceptive (OC) use. Caucasian Italian healthy non-obese women (n = 290; 100 OC-users; 190 non-OC-users; mean age 23.2 \ub1 4.7 years) were analyzed. Blood hydroperoxides, as oxidative stress biomarkers, were assessed by Free Oxygen Radical Test (FORT). Serum hsCRP was determined by an ultra-sensitive method (hsCRP). Markedly elevated oxidative stress ( 65400 FORT Units) was found in 77.0% of OC-users and 1.6% of non-OC-users, odds ratio (OR) = 209, 95% CI = 60.9-715.4, p < 0.001. Elevated hsCRP levels 65 2.0 mg/L, considered risky for cardiovascular diseases (CVDs), were found in 41.0% of OC-users and 9.5% of non-OC-users, OR = 6.6, 95%CI 3.5-12.4, p < 0.001. Hydroperoxides were strongly positively correlated to hsCRP in all women (rs = 0.622, p < 0.001), in OC-users (rs = 0.442, p < 0.001), and in non-OC-users (rs = 0.426, p < 0.001). Women with hydroperoxides 65 400 FORT Units were eight times as likely to have hsCRP 65 2 mg/L. In non-OC-users only, hydroperoxides values were positively correlated with weight and body mass index, but negatively correlated with red meat, fish and chocolate consumption. Our research is the first finding a strong positive correlation of serum hydroperoxides with hsCRP, a marker of low-grade chronic inflammation, in young healthy women. Further research is needed to elucidate the potential role of these two biomarkers in OC-use associated side-effects, like thromboembolism and other CVDs
Model theory of finite and pseudofinite groups
This is a survey, intended both for group theorists and model theorists, concerning the structure of pseudofinite groups, that is, infinite models of the first-order theory of finite groups. The focus is on concepts from stability theory and generalisations in the context of pseudofinite groups, and on the information this might provide for finite group theory
Valutazione stocastica di capacit\ue0 e regolarit\ue0 sulla rete ferroviaria tra Venezia e Trieste
Il fenomeno infortunistico nei lavoratori della cantieristica navale del cantiere di Monfalcone (Gorizia) dal 2000 al 2010.
Cutipositivit\ue0 a lattice e agli alimenti cross reagenti in un gruppo di infermieri in fase di assunzione
La qualit\ue0 totale in medicina del lavoro: l\u2019esperienza del coordinamento fra i medici competenti delle strutture sanitarie del Friuli-Venezia Giulia
Rilievi aerobiologici e sensibilizzazione a pollini di Oleaceae nella citt\ue0 di Trieste nel triennio 1995-1997.
E-learning courses at Italian National Institute of Health: characteristic of dropout partecipants
The 10th Meeting of PhD students in Infectious Diseases, Microbiology and Health Sciences will
be focused on the difficult and controversial relationship between democracy and science. While the
lack of knowledge-sharing behaviour can jeopardize the credibility of scientists, on the other hand
scientific data must be subjected only to rigorous validation and verification, not to public judgement
or to the appeal for the wide audience. We would like to deepen the connections between democracy
and science, a topic of particular concern in Public Healt