27 research outputs found
B7-H4 gene polymorphisms are associated with sporadic breast cancer in a Chinese Han population
© 2009 Zhang et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
Brief Report - Azithromycin as Treatment for Cryptosporidiosis in Human Immunodeficiency Virus Disease
Background: Cryptosporidiosis caused by the protozoa Cryptosporidium,
is the common cause of diarrhoea in Acquired Immune Deficiency Syndrome
(AIDS). Aim: To study the efficacy of short-term azithromycin in the
management of cryptosporidiosis. Settings and Design: Randomised,
controlled trial. Material and Methods: All consecutive patients
infected with Human Immunodeficiency Virus (HIV), who were positive for
cryptosporidial oocysts were taken for this prospective randomised
study. Result: Short-term azithromycin treatment for cryptosporidial
diarrhoea in AIDS patients was associated with good clinical
improvement but parasitological benefit was doubtful. All 13 patients,
who had symptoms of cryptosporidiosis, symptomatically improved with 5
days of treatment with azithromycin and became asymptomatic after 7
days of antibiotic, but stool sample was positive for cryptosporidium
even after 7 days of therapy. After 14 days of treatment with
azithromycin in 13 patients, in five patients stool was free of
cryptosporidial oocyst. The drug was well tolerated in all the
patients. Conclusion: Short-term azithromycin can be used as a safe and
effective treatment for symptomatic Cryptosporidiosis but not effective
in eradicating Cryptosporidial infection. (J Postgrad Med
2002;48:179-181
Mimic of cellulitis: Primary cutaneous B cell lymphoma – Leg type
Primary cutaneous B-cell lymphoma, leg type, is an uncommon and aggressive subtype of Primary cutaneous B cell lymphoma that is recently updated by the World Health Organization–European Organization for Research and Treatment of Cancer classification of cutaneous lymphomas. We present a case of an 80-year-old woman who presented with redness and swelling mimicking cellulitis of her right leg, along with few skin colored nodules. Skin biopsy revealed pathology consistent with this entity. The patient was treated with systemic chemotherapy, but expired while on treatment secondary to sepsis
Acute ingestion of copper sulphate: A review on its clinical manifestations and management
Ingestion of copper sulphate is an uncommon mode of poisoning in the
Indian subcontinent. Cases are mainly suicidal in nature. The clinical
course of the copper sulphate intoxicated patient is often complex
involving intravascular hemolysis, jaundice and renal failure. The
treatment is mainly supportive. In severe cases methemoglobinemia needs
treatment. Mortality is quite high in severe cases. A comprehensive
review of the clinical presentation and management of copper sulphate
poisoning is done