7,496 research outputs found

    Interferometric distillation and determination of unknown two-qubit entanglement

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    We propose a scheme for both distilling and quantifying entanglement, applicable to individual copies of an arbitrary unknown two-qubit state. It is realized in a usual two-qubit interferometry with local filtering. Proper filtering operation for the maximal distillation of the state is achieved, by erasing single-qubit interference, and then the concurrence of the state is determined directly from the visibilities of two-qubit interference. We compare the scheme with full state tomography

    A formalism for coupled design learning activities

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    This paper presents a formalism to represent the inextricable link that exists between design and learning. It provides an approach to study and analyse the complex relationships that may exist between design and learning. It suggests that design and learning are linked at the knowledge level (epistemic link), in a temporal manner and in a purposeful manner through the design and learning goal

    Knowledge transformers : a link between learning and creativity

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    The purpose of this paper is to investigate whether knowledge transformers which are featured in the learning process, are also present in the creative process. This is achieved by reviewing models and theories of creativity and identifying the existence of the knowledge transformers. The investigation shows that there is some evidence to show that the creative process can be explained through knowledge transformers. Hence, it is suggested that one of links between learning and creativity is through the knowledge transformers

    Complement activation and protein adsorption by carbon nanotubes

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    As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored. Haemolytic assays were conducted to investigate the activation of the human serum complement system via the classical and alternative pathways. Western blot and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) techniques were used to elucidate the mechanism of activation of complement via the classical pathway, and to analyse the interaction of complement and other plasma proteins with carbon nanotubes. We report for the first time that carbon nanotubes activate human complement via both classical and alternative pathways. We conclude that complement activation by nanotubes is consistent with reported adjuvant effects, and might also in various circumstances promote damaging effects of excessive complement activation, such as inflammation and granuloma formation. C1q binds directly to carbon nanotubes. Protein binding to carbon nanotubes is highly selective, since out of the many different proteins in plasma, very few bind to the carbon nanotubes. Fibrinogen and apolipoproteins (AI, AIV and CIII) were the proteins that bound to carbon nanotubes in greatest quantit

    Expert Finding by Capturing Organisational Knowledge from Legacy Documents

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    Organisations capitalise on their best knowledge through the improvement of shared expertise which leads to a higher level of productivity and competency. The recognition of the need to foster the sharing of expertise has led to the development of expert finder systems that hold pointers to experts who posses specific knowledge in organisations. This paper discusses an approach to locating an expert through the application of information retrieval and analysis processes to an organization’s existing information resources, with specific reference to the engineering design domain. The approach taken was realised through an expert finder system framework. It enables the relationships of heterogeneous information sources with experts to be factored in modelling individuals’ expertise. These valuable relationships are typically ignored by existing expert finder systems, which only focus on how documents relate to their content. The developed framework also provides an architecture that can be easily adapted to different organisational environments. In addition, it also allows users to access the expertise recognition logic, giving them greater trust in the systems implemented using this framework. The framework were applied to real world application and evaluated within a major engineering company

    Quantifying mixed-state quantum entanglement by optimal entanglement witness

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    We develop an approach of quantifying entanglement in mixed quantum states by the optimal entanglement witness operator. We identify the convex set of mixed states for which a single witness provides the exact value of an entanglement measure, and show that the convexity, properties, and symmetries of entanglement or of a target state considerably fix the form of the optimal witness. This greatly reduces difficulty in computing and experimentally determining entanglement measures. As an example, we show how to experimentally quantify bound entanglement in four-qubit noisy Smolin states and three-qubit Greenberger-Horne-Zeilinger (GHZ) entanglement under white noise. For general measures and states, we provide a numerical method to efficiently optimize witness.Comment: Supplemental material is include

    Human interleukin-1 receptor antagonist is expressed in liver

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    AbstractUsing PCR and Northern blot analysis, an IL-1 receptor antagonist specific transcript was amplified from HepG2- and liver mRNA, cDNA clones coding for IL-1 receptor antagonist were isolated from a liver cDNA library and sequence comparison revealed complete identity with the secreted, monocytic form of IL-1 receptor antagonist
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