1,758 research outputs found
Spin susceptibility of the superfluid He-B in aerogel
The temperature dependence of paramagnetic susceptibility of the superfluid
^{3}He-B in aerogel is found. Calculations have been performed for an arbitrary
phase shift of s-wave scattering in the framework of BCS weak coupling theory
and the simplest model of aerogel as an aggregate of homogeneously distributed
ordinary impurities. Both limiting cases of the Born and unitary scattering can
be easily obtained from the general result. The existence of gapless
superfluidity starting at the critical impurity concentration depending on the
value of the scattering phase has been demonstrated. While larger than in the
bulk liquid the calculated susceptibility of the B-phase in aerogel proves to
be conspicuously smaller than that determined experimentally in the high
pressure region.Comment: 10 pages, 4 figures, REVTe
Prevention of immunodeficiency virus induced CD4+ T-cell depletion by prior infection with a non-pathogenic virus
AbstractImmune dysregulation initiated by a profound loss of CD4+ T-cells is fundamental to HIV-induced pathogenesis. Infection of domestic cats with a non-pathogenic lentivirus prevalent in the puma (puma lentivirus, PLV or FIVpco) prevented peripheral blood CD4+ T-cell depletion caused by subsequent virulent FIV infection. Maintenance of this critical population was not associated with a significant decrease in FIV viremia, lending support to the hypothesis that direct viral cytopathic effect is not the primary cause of immunodeficiency. Although this approach was analogous to immunization with a modified live vaccine, correlates of immunity such as a serum-neutralizing antibody or virus-specific T-cell proliferative response were not found in protected animals. Differences in cytokine transcription profile, most notably in interferon gamma, were observed between the protected and unprotected groups. These data provide support for the importance of non-adaptive enhancement of the immune response in the prevention of CD4+ T-cell loss
Wound irrigation does not affect healthrelated quality of life after open fractures: Results of a randomized controlled trial
© 2018 Sprague et al. Aims The Fluid Lavage in Open Fracture Wounds (FLOW) trial was a multicentre, blinded, randomized controlled trial that used a 2 3 factorial design to evaluate the effect of irrigation solution (soap versus normal saline) and irrigation pressure (very low versus low versus high) on health-related quality of life (HRQL) in patients with open fractures. In this study, we used this dataset to ascertain whether these factors affect whether HRQL returns to pre-injury levels at 12-months post-injury. Patients and Methods Participants completed the Short Form-12 (SF-12) and the EuroQol-5 Dimensions (EQ-5D) at baseline (pre-injury recall), at two and six weeks, and at three, six, nine and 12-months postfracture. We calculated the Physical Component Score (PCS) and the Mental Component Score (MCS) of the SF-12 and the EQ-5D utility score, conducted an analysis using a multilevel generalized linear model, and compared differences between the baseline and 12- month scores. Results We found no clinically important differences between irrigating solutions or pressures for the SF-12 PCS, SF-12 MCS and EQ-5D. Irrespective of treatment, participants had not returned to their pre-injury function at 12-months for any of the three outcomes (p \u3c 0.001). Conclusion Neither the composition of the irrigation solution nor irrigation pressure applied had an effect on HRQL. Irrespective of treatment, patients had not returned to their pre-injury HRQL at 12 months post-fracture
Universal Behaviour of the Superfluid Fraction and Tc of He-3 in 99.5% Open Aerogel
We have investigated the superfluid transition of He-3 in a 99.5% porosity
silica aerogel. This very dilute sample shows behaviour intermediary between
bulk He-3 and He-3 confined to the denser aerogels previously studied. We
present data on both the superfluid transition temperature and the superfluid
density and compare our results with previous measurements. Finally, we show
that the suppression of the superfluid transition temperature and suppression
of the superfluid density of He-3 in aerogel follow a universal relation for a
range of aerogel samples.Comment: 4 pages, 5 figures; 1 new figure, minor change
Plasma-binding globulins and acute stress response
Within studies of acute stress physiology an increase in glucocorticoid secretion is thought to be the primary mediator of tissue response to stress. Corticosteroid-binding globulin may regulate tissue availability of steroids, but has not been considered a dynamic component of the acute stress response. Here, we examined CBG level over the common 60-minute time frame in an acute capture and handling protocol to investigate whether CBG capacity is dynamic or static over short stressors. Using a comparative approach, we measured CBG response to capture and handling stress in nine species of birds, representing five orders and nine families. CBG capacity significantly declined within 30-60 minutes of capture in five of the nine species examined. This decline may serve to significantly increase the level of corticosterone reaching tissues during acute stress. © Georg Thieme Verlag KG Stuttgart
Plasma-binding globulins and acute stress response
Within studies of acute stress physiology an increase in glucocorticoid secretion is thought to be the primary mediator of tissue response to stress. Corticosteroid-binding globulin may regulate tissue availability of steroids, but has not been considered a dynamic component of the acute stress response. Here, we examined CBG level over the common 60-minute time frame in an acute capture and handling protocol to investigate whether CBG capacity is dynamic or static over short stressors. Using a comparative approach, we measured CBG response to capture and handling stress in nine species of birds, representing five orders and nine families. CBG capacity significantly declined within 30-60 minutes of capture in five of the nine species examined. This decline may serve to significantly increase the level of corticosterone reaching tissues during acute stress. © Georg Thieme Verlag KG Stuttgart
Model of Inhomogeneous Impurity Distribution in Fermi Superfluids
The standard treatment of impurities in metals assumes a homogeneous
distribution of impurities. In this paper we study distributions that are
inhomogeneous. We discuss in detail the "isotropic inhomogeneous scattering
model" which takes into account the spatially varying scattering on the scale
of the superfluid coherence length. On a large scale the model reduces to a
homogeneous medium with renormalized parameter values. We apply the model to
superfluid 3He, where porous aerogel acts as the impurity. We calculate the
transition temperature Tc, the order parameter, and the superfluid density.
Both A- and B-like phases are considered. Two different types of behavior are
identified for the temperature dependence of the order parameter. We compare
the calculations with experiments on 3He in aerogel. We find that most of the
differences between experiments and the homogeneous theory can be explained by
the inhomogeneous model. All our calculations are based on the quasiclassical
theory of Fermi liquids. The parameters of this theory for superfluid 3He in
aerogel are discussed.Comment: 14 pages, 9 figures, minor change
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