2,325 research outputs found

    A tale of two crises

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    Federal funds rate

    Freezing Transition of Random Heteropolymers Consisting of an Arbitrary Set of Monomers

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    Mean field replica theory is employed to analyze the freezing transition of random heteropolymers comprised of an arbitrary number (qq) of types of monomers. Our formalism assumes that interactions are short range and heterogeneity comes only from pairwise interactions, which are defined by an arbitrary qĂ—qq \times q matrix. We show that, in general, there exists a freezing transition from a random globule, in which the thermodynamic equilibrium is comprised of an essentially infinite number polymer conformations, to a frozen globule, in which equilibrium ensemble is dominated by one or very few conformations. We also examine some special cases of interaction matrices to analyze the relationship between the freezing transition and the nature of interactions involved.Comment: 30 pages, 1 postscript figur

    Reductive Biotransformation of Ethyl Acetoacetate: A Comparative Studies using Free and Immobilized Whole Yeast Cells

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    Bioreduction of ethyl acetoacetate with free and immobilized yeast whole cell was achieved by using water and sucrose combination. After detachment from immobilized beads under basic condition, the corresponding ethyl(S)-(+)-3-hydroxybutanoate was isolated with 98 to 100% yield. Immobilized beads of yeast whole cell were prepared at different temperature which affects the morphology and physiology of the beads for the diffusion of the enzyme, which shown the maximum conversion of the substrate to products as compared to the free yeast whole cell

    Anemia in Antiretroviral NaĂŻve HIV/AIDS Patients: A Study from Eastern India

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    Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a non randomized cross sectional observational study conducted in a tertiary care hospital of India over a period of 2 years. One hundred and fifty HIV patients were screened. Thorough clinical and laboratory evaluation was done in 50 randomly selected anemic cases. Results: Proper etiological diagnosis could be reached in 46 patients. Among them correlation between Hb% and CD4 count was statistically insignificant (p = 0.074, r = 0.47) whereas it was significant with absolute lymphocyte and CD4 count (p = 0.006, r = 0.41). There was better correlation of bone marrow iron status with percent saturation of transferrin (p = 0.003, r = 0.54) than with serum ferritin (p = 0.055, r = 0.09). Bone marrow iron status did not have any relationship with CD4 count. Anemia of chronic disease was the commonest etiology (37%) followed by HIV related myelodysplastic syndrome (31%), iron deficiency anemia (13%), bone marrow suppression due to direct involvement by some infective process (7%). Aplastic anemia, multiple myeloma, Hodgkin’s disease, pure red cell aplasia, hemophagocytic lymphohistiocytosis and vitamin B12 deficiency were detected in one case (2%) each. Conclusions: Etiologies of anemia in HIV/AIDS are multifactorial with anemia of chronic disease being the commonest. For screening of iron deficiency in this group, percent saturation is a better tool than serum ferritin. Absolute lymphocyte count can sometimes be used as a surrogate marker of immunological status in antiretroviral naïve HIV patients, particularly in resource poor areas

    “BE YOURSELF” (the Creation of a Music Composition)

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    An artistic workmanship is a creative work process of an artist in creating artworks. Artwork meant by the writer is "Be Yourself", which is related to the establishment of his self-characters that grown up in Sundanese culture. Life journey was a dynamic process and became the will of the Almighty. God's destiny and life journey made the writer as “urangsumando” (people related by marriage) in Minangkabau. Cross-cultural was a life journey to be (yourself) and the destiny he should do – being in two different culture positions. Such differences did not automatically make the writer soluble in integration – he existed in two conceptions. In the realization, how the concepts are able to deliver other offers which have contribution to the development of artistic creation. The discussion in this article is the artistic forms as the exploration, working material, and forms of performance
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