1,122 research outputs found

    The Climate Gap: Inequalities in How Climate Change Hurts Americans & How to Close the Gap

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    By now, virtually all Americans concur that climate change is real, and could pose devastating consequences for our nation and our children. Equally real is the "Climate Gap" -- the sometimes hidden and often-unequal impact climate change will have on people of color and the poor in the United States. This report helps to document the Climate Gap, connecting the dots between research on heat waves, air quality, and other challenges associated with climate change. But we do more than point out an urgent problem; we also explore how we might best combine efforts to both solve climate change and close the Climate Gap -- including an appendix focused on California's global warming policy and a special accompanying analysis of the federal-level American Clean Energy Security Act

    Banding pattern indicative of echinococcosis in a commercial cysticercosis western blot

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    <p>Abstract</p> <p>Objective</p> <p>A commercial cysticercosis Western blot was evaluated for serological cross-reactivity of sera from patients with alveolar (AE) and cystic echinococcosis (CE).</p> <p>Methods</p> <p>A total of 161 sera were examined, including 31 sera from AE-patients, 11 sera from CE-patients, 9 sera from patients with other parasitic diseases and 109 sera from patients with unrelated medical conditions. All AE-and CE-sera were also examined by the echinococcosis Western blot.</p> <p>Results</p> <p>More sera from patients with AE than with CE showed cross-reactivity in the form of ladder-like patterns ("Mikado aspect") and untypical bands at 6-8 kDa (71% and 77.4% versus 27.3% and 45.5%, respectively). In contrast, triplets of bands in the area above 50 kDa and between 24 and 39-42 kDa were more frequent in CE than in AE sera. The fuzzy band at 50-55 kDa typical for cysticercosis was absent in all AE and CE sera.</p> <p>Conclusions</p> <p>Atypical banding patterns in the cysticercosis Western blot should raise the suspicion of a metacestode infection different from Taenia solium, i.e. Echinococcus multilocularis or E. granulosus, especially when the Mikado aspect and an altered 6-8 kDa band is visible in the absence of a fuzzy 50-55 kDa band.</p

    Repair and Strengthening of Bridges in Indiana Using Fiber Reinforced Polymer Systems: Volume 1–Review of Current FRP Repair Systems and Application Methodologies

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    For bridges that are experiencing deterioration, action is needed to ensure the structural performance is adequate for the demands imposed. Innovate repair and strengthening techniques can provide a cost-effective means to extend the service lives of bridges efficiently and safely. The use of fiber reinforced polymer (FRP) systems for the repair and strengthening of concrete bridges is increasing in popularity. Recognizing the potential benefits of the widespread use of FRP, a research project was initiated to determine the most appropriate applications of FRP in Indiana and provide recommendations for the use of FRP in the state for the repair and strengthening of bridges. The details of the research are presented in two volumes. Volume 1 provides the details of a study conducted to (1) summarize the state-of-the-art methods for the application of FRP to concrete bridges, (2) identify successful examples of FRP implementation for concrete bridges in the literature and examine past applications of FRP in Indiana through case studies, and (3) better understand FRP usage and installation procedures in the Midwest and Indiana through industry surveys. Volume 2 presents two experimental programs that were conducted to develop and evaluate various repair and strengthening methodologies used to restore the performance of deteriorated concrete bridge beams. The first program investigated FRP flexural strengthening methods, with a focus on adjacent box beam bridges. The second experimental program examined potential techniques for repairing deteriorated end regions of prestressed concrete bridge girders. Externally bonded FRP and near-surface-mounted (NSM) FRP were considered in both programs

    Repair and Strengthening of Bridges in Indiana Using Fiber Reinforced Polymer Systems: Volume 2–FRP Flexural Strengthening and End Region Repair Experimental Programs

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    For bridges that are experiencing deterioration, action is needed to ensure the structural performance is adequate for the demands imposed. Innovate repair and strengthening techniques can provide a cost-effective means to efficiently and safely extend the service lives of bridges. The use of fiber reinforced polymer (FRP) systems for the repair and strengthening of concrete bridges is increasing in popularity. Recognizing the potential benefits of the widespread use of FRP, a research project was initiated to determine the most appropriate applications of FRP in Indiana and provide recommendations for the use of FRP in the state for the repair and strengthening of bridges. The details of the research are presented in two volumes. Volume 1 provides the details of a study conducted to (i) summarize the state-of-the-art for the application of FRP to concrete bridges, (ii) identify successful examples of FRP implementation for concrete bridges in the literature and examine past applications of FRP in Indiana through case studies, and (iii) better understand FRP usage and installation procedures in the Midwest and Indiana through industry surveys. Volume 2 presents two experimental programs that were conducted to develop and evaluate various repair and strengthening methodologies used to restore the performance of deteriorated concrete bridge beams. The first program investigated FRP flexural strengthening methods, with focus placed on adjacent box beam bridges. The second experimental program examined potential techniques for repairing deteriorated end regions of prestressed concrete bridge girders. Externally bonded FRP and near-surface-mounted (NSM) FRP were considered in both programs

    Effects of the Neutron Spin-Orbit Density on Nuclear Charge Density in Relativistic Models

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    The neutron spin-orbit density contributes to the nuclear charge density as a relativistic effect. The contribution is enhanced by the effective mass stemming from the Lorentz-scalar potential in relativistic models. This enhancement explains well the difference between the cross sections of elastic electron scattering off 40^{40}Ca and 48^{48}Ca which was not reproduced in non-relativistic models. The spin-orbit density will be examined in more detail in electron scattering off unstable nuclei which would be available in the future.Comment: 4 pages with 3 eps figures, revte

    Physical and chemical stability of expired fixed dose combination artemether-lumefantrine in uncontrolled tropical conditions

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    <p>Abstract</p> <p>Background</p> <p>New artemisinin combination therapies pose difficulties of implementation in developing and tropical settings because they have a short shelf-life (two years) relative to the medicines they replace. This limits the reliability and cost of treatment, and the acceptability of this treatment to health care workers. A multi-pronged investigation was made into the chemical and physical stability of fixed dose combination artemether-lumefantrine (FDC-ALU) stored under heterogeneous, uncontrolled African conditions, to probe if a shelf-life extension might be possible.</p> <p>Methods</p> <p>Seventy samples of expired FDC-ALU were collected from private pharmacies and malaria researchers in seven African countries. The samples were subjected to thin-layer chromatography (TLC), disintegration testing, and near infrared Raman spectrometry for ascertainment of active ingredients, tablet integrity, and chemical degradation of the tablet formulation including both active ingredients and excipients.</p> <p>Results</p> <p>Seventy samples of FDC-ALU were tested in July 2008, between one and 58 months post-expiry. 68 of 70 (97%) samples passed TLC, disintegration and Raman spectrometry testing, including eight samples that were post-expiry by 20 months or longer. A weak linear association (R<sup>2 </sup>= 0.33) was observed between the age of samples and their state of degradation relative to brand-identical samples on Raman spectrometry. Sixty-eight samples were retested in February 2009 using Raman spectrometry, between eight and 65 months post-expiry. 66 of 68 (97%) samples passed Raman spectrometry retesting. An unexpected observation about African drug logistics was made in three batches of FDC-ALU, which had been sold into the public sector at concessional pricing in accordance with a World Health Organization (WHO) agreement, and which were illegally diverted to the private sector where they were sold for profit.</p> <p>Conclusion</p> <p>The data indicate that FDC-ALU is chemically and physically stable well beyond its stated shelf-life in uncontrolled, tropical conditions. While these data are not themselves sufficient, it is strongly suggested that a re-evaluation of the two-year shelf-life by drug regulatory authorities is warranted.</p

    Material reutilization cycles across industries and production lines

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    The concept of Industrial Symbiosis aims at organizing industrial activity like a living ecosystem where the by-product outputs of one process are used as valuable raw material input for another process. A significant method for the systematic planning of Industrial Symbiosis is found in input–output matching, which is aimed at collecting material input and output data from companies, and using the results to establish links across industries. The collection and classification of data is crucial to the development of synergies in Industrial Symbiosis. Public and private institutions involved in the planning and development of Industrial Symbiosis rely however on manual interpretation of information in the course of creating synergies. Yet, the evaluation and analysis of these data sources on Industrial Symbiosis topics is a tall order. Within this chapter a method is presented which describes value creation activities according to the Value Creation Module (VCM). They are assessed before they are integrated in Value Creation Networks (VCNs), where alternative uses for by-products are proposed by means of iterative input-output matching of selected value creation factors

    Photo- and Electro-Disintegration of 3He at Threshold and pd Radiative Capture

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    The present work reports results for: pd radiative capture observables measured at center-of-mass (c.m.) energies in the range 0--100 keV and at 2 MeV by the TUNL and Wisconsin groups, respectively; contributions to the Gerasimov-Drell-Hearn (GDH) integral in 3He from the two- up to the three-body breakup thresholds, compared to experimental determinations by the TUNL group in this threshold region; longitudinal, transverse, and interference response functions measured in inclusive polarized electron scattering off polarized 3He at excitation energies below the threshold for breakup into ppn, compared to unpolarized longitudinal and transverse data from the Saskatoon group. The calculations are based on a realistic Hamiltonian with two- and three-nucleon interactions and a realistic current operator, including one- and two-body components. The theoretical predictions obtained by including only one-body currents are in violent disagreement with data. These differences between theory and experiment are, to a large extent, removed when two-body currents are taken into account, although some rather large discrepancies remain in the c.m. energy range 0--100 keV, particularly for the pd differential cross section and tensor analyzing power at small angles, and contributions to the GDH integral. A rather detailed analysis indicates that these discrepancies have, in large part, a common origin, and can be traced back to an excess strength obtained in the theoretical calculation of the E1 reduced matrix element associated with the pd channel having L,S,J=1,1/2,3/2. It is suggested that this lack of E1 strength observed experimentally might have implications for the nuclear interaction at very low energies. Finally, the validity of the long-wavelength approximation for electric dipole transitions is discussed.Comment: 47 pages RevTex file, 10 PostScript figures, submitted to Phys. Rev.

    Narratives of ethnic identity among practitioners in community settings in the northeast of England

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    The increasing ethnic diversity of the UK has been mirrored by growing public awareness of multicultural issues, alongside developments in academic and government thinking. This paper explores the contested meanings around ethnic identity/ies in community settings, drawing on semi-structured interviews with staff from Children’s Centres and allied agencies conducted for a research project that examined the relationship between identity and the participation of parents/carers in services in northeast England. The research found that respondents were unclear about, especially, white ethnic identities, and commonly referred to other social categorizations, such as age, nationality, and circumstances such as mobility, when discussing service users. While in some cases this may have reflected legitimate attempts to resist overethnicizing non-ethnic phenomena, such constructions coexisted with assumptions about ethnic difference and how it might translate into service needs. These findings raise important considerations for policy and practice
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